Recombinant Human PITPNA, His-tagged

• Cat.No.: PITPNA-3381H
• Product Overview: Recombinant human PITPNA protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.MW = 33.9 kDa (290aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Phosphatidylinositol transfer protein alpha, also known PITPNA, is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. PITPNA is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 1mM EDTA.
• Purity: > 95% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MVLLKEYRVI LPVSVDEYQV GQLYSVAEAS KNETGGGEGV EVLVNEPYEK DGEKGQYTHK IYHLQSKVPT FVRMLAPEGA LNIHEKAWNA YPYCRTVITN EYMKEDFLIK IETWHKPDLG TQENVHKLEP EAWKHVEAVY IDIADRSQVL SKDYKAEEDP AKFKSIKTGR GPLGPNWKQE LVNQKDCPYM CAYKLVTVKF KWWGLQNKVE NFIHKQERRL FTNFHRQLFC WLDKWVDLTM DDIRRMEEET KRQLDEMRQK DPVKGMTADD.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Axon guidance

Gene Information

• Gene Name: PITPNA phosphatidylinositol transfer protein, alpha [ Homo sapiens ]
• Synonyms: phosphatidylinositol transfer protein, alpha; PITPN; VIB1A; MGC99649; PI-TPalpha; PITPNA; phosphatidylinositol transfer protein alpha isoform; PI-TP-alpha; ptdInsTP alpha; ptdIns transfer protein alpha; PtdInsTP alpha; PtdIns transfer protein alpha
• Gene ID: 5306
• mRNA Refseq: NM_006224
• Protein Refseq: NP_006215
• MIM: 600174
• UniProt ID: Q00169
• Chromosome Location: 17p13.3
• Function: phosphatidylcholine transmembrane transporter activity; phosphatidylinositol transporter activity; phospholipid binding; protein binding