plg
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  • Official Full Name
  • plasminogen
  • Background
  • The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • PLG; plasminogen; EC 3.4.21.7; DKFZp779M0222; plasmin; EC 3.4.21
Cat.#:PLG-1107HTag:Fc
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human PLG Protein, Fc Chimera
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Cat.#:PLG-155HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Plasminogen
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Cat.#:PLG-1786HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLG, GST-tagged
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Cat.#:PLG-31454THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLG
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Cat.#:PLG-4186HTag:N/A
Source (Host):Human FluidsSpecies:Human
Product nameRecombinant Human Plasminogen
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Cat.#:PLG-437HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human PLG protein, His-tagged
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Cat.#:PLG-5850HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLG protein, His-tagged
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Cat.#:PLG-66HTag:N/A
Source (Host):YeastSpecies:Human
Product nameRecombinant Human Plasminogen
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Cat.#:PLG-67HTag:
Source (Host):PichiaSpecies:Human
Product nameRecombinant Human PLG Protein
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Cat.#:PLG-9029HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human PLG protein, GST-tagged
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Cat.#:PLG-12970MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PLG Protein
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Cat.#:Plg-5851MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Plg protein, His-tagged
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Cat.#:PLG-4522RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PLG Protein
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Cat.#:Plg-573RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Plg protein, His-tagged
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Cat.#:Plg-6730RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Plg protein, His & GST-tagged
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Cat.#:PLG-3472RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PLG Protein, His-tagged
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Cat.#:PLG-11518ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PLG
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Cat.#:PLG-15HTag:
Source (Host):Species:Human
Product nameNative Human Plasminogen Protein
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Cat.#:PLG-252HTag:
Source (Host):Species:Human
Product nameNative Human Plasminogen
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Cat.#:PLG-27842THTag:
Source (Host):Species:Human
Product nameNative Human PLG
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Cat.#:PLG-27925THTag:
Source (Host):Species:Human
Product nameNative Human PLG
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Cat.#:PLG-30083THTag:
Source (Host):Species:Human
Product nameNative Human PLG
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Cat.#:PLG-30879THTag:
Source (Host):Species:Human
Product nameNative Human PLG
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Cat.#:PLG-30880THTag:
Source (Host):Species:Human
Product nameNative Human PLG
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Cat.#:PLG-54HTag:
Source (Host):Species:Human
Product nameNative Human glu-Plasminogen
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Cat.#:PLG-55HTag:
Source (Host):Species:Human
Product nameNative Human lys-Plasminogen
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Cat.#:PLG-8HTag:N/A
Source (Host):Species:Human
Product nameNative Human Plasminogen, FITC Labeled
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Cat.#:Plg-291MTag:
Source (Host):Species:Mouse
Product nameNative Mouse glu-Plasminogen
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Cat.#:Plg-297MTag:
Source (Host):Species:Mouse
Product nameNative Mouse Plasmin
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Cat.#:Plg-32MTag:
Source (Host):Mouse PlasmaSpecies:Mouse
Product nameNative Mouse Plg protein
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Cat.#:Plg-5356MTag:
Source (Host):Mouse plasmaSpecies:Mouse
Product nameNative Mouse Plg protein
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Cat.#:Plg-1897RTag:N/A
Source (Host):Rat plasmaSpecies:Rat
Product nameNative Rat Plasminogen
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Cat.#:Plg-5465RTag:N/A
Source (Host):Rat plasmaSpecies:Rat
Product nameNative Rat Plasminogen
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Cat.#:PLG -37DTag:N/A
Source (Host):Species:Dog
Product nameNative Canine plasminogen
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Cat.#:PLG-1867BTag:N/A
Source (Host):Bovine PlasmaSpecies:Bovine
Product nameNative Bovine Plasminogen
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Cat.#:PLG-268BTag:
Source (Host):Species:Bovine
Product nameNative Bovine glu-Plasminogen
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Cat.#:PLG -38CTag:N/A
Source (Host):Species:Chicken
Product nameNative Chicken plasmin
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Cat.#:PLG -62RTag:N/A
Source (Host):Species:Rabbit
Product nameNative Rabbit plasmin
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Cat.#:PLG-3109HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PLG 293 Cell Lysate
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Cat.#:PLG-161HTag:
Source (Host):Species:Human
Product nameHuman Plasmin Reference standard
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Cat.#:Plg-53MTag:N/A
Source (Host):Species:Mouse
Product nameMouse Plasminogen Reference Standard
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Cat.#:Plg-87RTag:N/A
Source (Host):Species:Rat
Product nameRat Plasminogen Reference Standard
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Cat.#:PLG-23DTag:N/A
Source (Host):Species:Dog
Product nameDog Plasminogen Reference Standard
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Cat.#:PLG -66RTag:N/A
Source (Host):Species:Rabbit
Product nameRabbit Plasminogen Reference Standard
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Cat.#:PLG-62PTag:N/A
Source (Host):Species:Pig
Product namePig Plasminogen Reference Standard
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Involved Pathway

PLG involved in several pathways and played different roles in them. We selected most pathways PLG participated on our site, such as Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Neuroactive ligand-receptor interaction
PRLHR2A; TAAR14L; HTR1AB; HTR7; TAAR12G; BDKRB1; ADORA1; TAAR13C; FPR1; OXTR
Complement and coagulation cascades
PLAU; SERPINA1A; CD59A; GM5077; F9; CD59; BDKRB2; C6; CFB; SERPIND1
Staphylococcus aureus infection
HLA-DPB1; HLA-DOA; ITGB2L; FCGR3; C2; FCGR4; HLA-DRA; ICAM1; FCGR2A; CFH
Influenza A
DNAJC3; MYD88; TLR3; TMPRSS2; RAE1; CPSF4; HLA-DRA; NLRP3; IRF7; GSK3B

Protein Function

PLG has several biochemical functions, for example, apolipoprotein binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLG itself. We selected most functions PLG had, and list some proteins which have the same functions with PLG. You can find most of the proteins on our site.
Function
Related Protein
Function apolipoprotein binding
Related Protein MAPT; LRP1; SCARB1; LRP6; PLG; ABCA1; PCSK9; LIPC; CANX; VLDLR
Function protein binding
Related Protein SCIMP; GP5; PCK2; ZNF133; MS4A1; MC4R; ERCC5; CIB4; PHF1; SCO2
Function protein domain specific binding
Related Protein YWHAH; ZBTB16; SCAF1; GABRR2; STAMBP; SNCA; BASP1; HIST1H4N; XPA; YWHAQA
Function receptor binding
Related Protein TESPA1; FGF13A; ACOX3; ALCAM; P2RX7; BMP2; BAAT; WIPI1; ACOX2; FGF10A
Function serine-type endopeptidase activity
Related Protein LOC100686744; F9; OVCH2; TMPRSS11F; HP; GZMA; KLK1B24; CLPP; HGF; F10
Function serine-type peptidase activity
Related Protein KLK1B16; C1R; KLK12; ELA2; KLK1B24; DPP8; TMPRSS12; Acr; KLK1B22; KLK1B26

Interacting Protein

PLG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLG here. Most of them are supplied by our site. Hope this information will be useful for your research of PLG.
q6v4l1_strpy; q6v4l4_strpy; q6v4l5_strpy; q6v4l9_strpy; sak; ATP2; ATP1; ATP15

PLG Related Articles

Kurtulus-Waschulewski, I; Wahl, G; et al. Letter regarding the article: "Root dentin anomaly and a PLG mutation" by Tananuvat et al. EUROPEAN JOURNAL OF MEDICAL GENETICS 58:199-200(2015).
Munakata, S; Tashiro, Y; et al. Inhibition of Plasmin Protects Against Colitis in Mice by Suppressing Matrix Metalloproteinase 9-Mediated Cytokine Release From Myeloid Cells. GASTROENTEROLOGY 148:565-+(2015).