Native Rat Plasminogen

• Cat.No.: Plg-1897R
• Product Overview: Native rat Plg wasexpressed in rat plasma.

Specification

• Species: Rat
• Source: Rat plasma
• Tag: Non
• Description: Plg is acirculating zymogen that is converted to the active enzyme Plasminby cleavage of the peptide bond between Arg-560 and Val-561, which is mediatedby Urokinase (uPA/PLAU) and Tissue Plasminogen Activator (tPA/PLAT). The mainfunction of Plasmin is to dissolve Fibrin blood clots. Plasmin, like Trypsin,belongstothe family of serine proteases Fibrin is a cofactor for Plasminogenactivation by tPA.
• Form: Frozen Liquid in 0.1M HEPES + 0.1 M NaCl pH 7.4.
• Molecular Weight: 85 kDa
• Concentration: 10.0 mg/mL
• Storage: Store at -70°C.
• Pathways: Blood ClottingCascade; Complement and Coagulation Cascades; Complement and coagulationcascades; Diabetes pathways; Dissolution of Fibrin Clot; Hemostasis;Influenza A; LDL-mediated lipid transport; Lipid digestion; Lipoproteinmetabolism; Metabolism of lipids and lipoproteins; Neuroactiveligand-receptor interaction; Platelet activation; Platelet degranulation;Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-likeGrowth Factor Binding Proteins (IGFBPs)

Gene Information

• Gene Name: Plg plasminogen [ Rattusnorvegicus ]
• Official Symbol: Plg
• Synonyms: Plg; plasminogen; Ab1-346
• Gene ID: 85253
• mRNA Refseq: NM_053491
• Protein Refseq: NP_445943
• Chromosome Location: 1q11
• Function: apolipoproteinbinding; cell surface binding; endopeptidase activity; peptidase activity;serine-type endopeptidase activity