PPP1R15A Protein, protein phosphatase 1, regulatory subunit 15A


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Official Full Name protein phosphatase 1, regulatory subunit 15A
Background This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
Synonyms PPP1R15A; protein phosphatase 1, regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1 regulatory subunit 15A; GADD34; growth arrest and DNA damage inducible 34; growth arrest and DNA-damage-inducible 34
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP1R15A-1943H Recombinant Human PPP1R15A Protein (40-674 aa), His-tagged Yeast His
    Human PPP1R15A-15H Recombinant Human PPP1R15A Protein, GST-tagged Wheat Germ GST
    Human PPP1R15A-2943H Recombinant Human PPP1R15A protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human PPP1R15A-2943HCL Recombinant Human PPP1R15A 293 Cell Lysate HEK293 N/A
    Mouse Ppp1r15a-397M Recombinant Mouse Ppp1r15a Protein, His-tagged E.coli His
    Rat Ppp1r15a-398R Recombinant Rat Ppp1r15a Protein, His-tagged E.coli His
    Rat PPP1R15A-4619R Recombinant Rat PPP1R15A Protein Mammalian Cell His
    Zebrafish PPP1R15A-5291Z Recombinant Zebrafish PPP1R15A Mammalian Cell His

    PPP1R15A involved in several pathways and played different roles in them. We selected most pathways PPP1R15A participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R15A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein processing in endoplasmic reticulum ATXN3L; SEC61AL2; VCP; BAX; SSR4; BAG1; UBE2D3; NGLY1; SAR1AB; UBE2D4

    PPP1R15A has several biochemical functions, for example, protein binding, protein kinase binding, protein phosphatase 1 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R15A itself. We selected most functions PPP1R15A had, and list some proteins which have the same functions with PPP1R15A. You can find most of the proteins on our site.

    Function Related Protein
    protein binding KNDC1; TGFBR1; FGF1; SEPT11; PTGDR; DHX40; ANK2; HEMK1; ACD; WIPF2
    protein kinase binding CDKN2D; TEX14; DNM1; FZD5; HSPB1; STK11IP; FAF1; ADRA2A; SNAP91; SMAD3
    protein phosphatase 1 binding STAU1; PPP1R9B; LILRB2; PHACTR3B; PHACTR3A; PPP1R15A; PPP1R11; SHOC2; SH3RF2; FER
    protein phosphatase type 1 activator activity PPP1R15A; PHACTR4B; PHACTR4
    protein phosphatase type 1 regulator activity PHACTR3A; PHACTR4B; PHACTR3B; PHACTR1; PPP1R16B; UBXN2A; UBXN2B; PPP1R15A; NSFL1C; KCNS1

    PPP1R15A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R15A here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R15A.

    CTBP2; PPP1R1A; Dlg4; microcystin-lr; MYC; POU3F3; BCAR1; PPP1CA; trpE; q81l21_bacan; secA2; q81w74_bacan; ZNF512B

    Ohri, SS; Mullins, A; et al. Inhibition of GADD34, the Stress-Inducible Regulatory Subunit of the Endoplasmic Reticulum Stress Response, Does Not Enhance Functional Recovery after Spinal Cord Injury. PLOS ONE 9:-(2014).
    Yong, KJ; Milenic, DE; et al. Impact of alpha-Targeted Radiation Therapy on Gene Expression in a Pre-Clinical Model for Disseminated Peritoneal Disease when Combined with Paclitaxel. PLOS ONE 9:-(2014).

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