Recombinant Human PPP1R15A Protein (40-674 aa), His-tagged
Cat.No. : | PPP1R15A-1943H |
Product Overview : | Recombinant Human PPP1R15A Protein (40-674 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 71.1 kDa |
Protein length : | 40-674 aa |
AA Sequence : | GPLEPWLVEAVKGAALVEAGLEGEA RTPLAIPHTPWGRRPEEEAEDSGGP GEDRETLGLKTSSSLPEAWGLLDDD DGMYGEREATSVPRGQGSQFADGQR APLSPSLLIRTLQGSDKNPGEEKAE EEGVAEEEGVNKFSYPPSHRECCPA VEEEDDEEAVKKEAHRTSTSALSPG SKPSTWVSCPGEEENQATEDKRTER SKGARKTSVSPRSSGSDPRSWEYRS GEASEEKEEKAHKETGKGEAAPGPQ SSAPAQRPQLKSWWCQPSDEEEGEV KALGAAEKDGEAECPPCIPPPSAFL KAWVYWPGEDTEEEEDEEEDEDSDS GSDEEEGEAEASSSTPATGVFLKSW VYQPGEDTEEEEDEDSDTGSAEDER EAETSASTPPASAFLKAWVYRPGED TEEEEDEDVDSEDKEDDSEAALGEA ESDPHPSHPDQRAHFRGWGYRPGKE TEEEEAAEDWGEAEPCPFRVAIYVP GEKPPPPWAPPRLPLRLQRRLKRPE TPTHDPDPETPLKARKVRFSEKVTV HFLAVWAGPAQAARQGPWEQLARDR SRFARRITQAQEELSPCLTPAARAR AWARLRNPPLAPIPALTQTLPSSSV PSSPVQTTPLSQAVATPSRSSAAAA AALDLSGRRG |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | PPP1R15A protein phosphatase 1, regulatory subunit 15A [ Homo sapiens ] |
Official Symbol : | PPP1R15A |
Synonyms : | PPP1R15A; GADD34; growth arrest and DNA damage inducible 34; |
Gene ID : | 23645 |
mRNA Refseq : | NM_014330 |
Protein Refseq : | NP_055145 |
MIM : | 611048 |
UniProt ID : | O75807 |
Products Types
◆ Recombinant Protein | ||
Ppp1r15a-398R | Recombinant Rat Ppp1r15a Protein, His-tagged | +Inquiry |
PPP1R15A-4278R | Recombinant Rat PPP1R15A Protein, His (Fc)-Avi-tagged | +Inquiry |
Ppp1r15a-5064M | Recombinant Mouse Ppp1r15a Protein, Myc/DDK-tagged | +Inquiry |
Ppp1r15a-397M | Recombinant Mouse Ppp1r15a Protein, His-tagged | +Inquiry |
PPP1R15A-4619R | Recombinant Rat PPP1R15A Protein | +Inquiry |
◆ Lysates | ||
PPP1R15A-2943HCL | Recombinant Human PPP1R15A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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