prkcb
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  • Official Full Name
  • protein kinase C, beta
  • Background
  • plays a role in hexosamine biosynthesis pathway induced transcriptional regulation
  • Synonyms
  • Prkcb; protein kinase C, beta; Pkcb; Prkcb1; protein kinase C beta type; PKC-beta; protein kinase C beta I; protein kinase C beta
Cat.#:PRKCB-1953HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRKCB, GST-tagged
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Cat.#:PRKCB-399HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, GST-tagged, Active
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Cat.#:PRKCB-400HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, GST-tagged, Active
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Cat.#:PRKCB-59HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, 2-671aa, His-tagged
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Cat.#:PRKCB-60HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, 2-673aa, His-tagged
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Cat.#:PRKCB-649HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta
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Cat.#:PRKCB-13362MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PRKCB Protein
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Cat.#:Prkcb-1430RTag:His|S
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Prkcb protein, His & S-tagged
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Cat.#:PRKCB-4677RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PRKCB Protein
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Cat.#:PRKCB-3605RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PRKCB Protein, His-tagged
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Cat.#:PRKCB-1431RTag:His|S
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit PRKCB protein, His & S-tagged
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Cat.#:PRKCB-1302HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, GST-tagged
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Cat.#:PRKCB-2859HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PRKCB 293 Cell Lysate
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Involved Pathway

PRKCB involved in several pathways and played different roles in them. We selected most pathways PRKCB participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
TRP53; ELK4; MAPK8IP2; MEF2C; CACNA1C; FGF4; CACNG6A; TRAF6; ECSIT; CACNG4
ErbB signaling pathway
PIK3CD; PAK2A; PLCG2; PTK2; PTK2AB; PAK4; RAF1; RAF1B; BAD; GRB2B
Ras signaling pathway
FOXO4; AKT1; GAB2; RRAS; GNG3; LAT; RASSF1; LOC608458; STK4; GNG12
Rap signaling pathway
CALM1; MAPK11; BRAF; MAPK3; PLCB1; MET; BCAR1; ITGA2B; SIPA1L1; FGF3
Calcium signaling pathway
RYR3; ORAI1; PHKB; PTAFR; ADRA1D; P2RX2; ORAI3; SLC25A5; CACNA1C; CHRNA7
Chemokine signaling pathway
GRK7; ARRB1; HCK; CXCL11; NCF1; PARD3; SRC; PRKCZ; CCL3L3; STAT5B
NF-kappa B signaling pathway
TRIM25; GADD45B; BIRC2; IL1R1; TRAF2; PRKCQ; CCL21B; BIRC3; CCL19; XIAP
HIF- signaling pathway
PGK1; SLC2A1; TF; NOS2; PLCG1; MKNK2; ANGPT4; PLCG2; PIK3CB; EIF4E1B
Phosphatidylinositol signaling system
PIK3R3B; PLCG1; PIKFYVE; INPP4AB; ITPR1; MTMR8; PRKCBB; CALML3; PIP4K2A; PIP5K1BA
Sphingolipid signaling pathway
MAPK13; MAP2K2; MS4A2; FCER1A; FCER1G; PLCB2; PPP2R2C; PPP2R5A; ACER1; RAC1
mTOR signaling pathway
RPS6KA2; RPS6KB1; PRKAA1; TSC1B; HIF1AB; INS; RPS6KA3A; EIF4E1B; EIF4E2RS1; RPS6
Vascular smooth muscle contraction
GNA12A; CALM2; CALD1; GNAQ; PRKACBA; MYL12.1; NPR1A; PLA2G2D; PLA2G4AA; PLCB3
Wnt signaling pathway
SKP1; CAMK2D2; PORCN; PRICKLE2B; WNT7A; PRKACBA; SFRP1A; RHOAA; BAMBIA; FZD1
VEGF signaling pathway
PPP3CC; AKT2; HRASB; PTGS2B; KRAS; CDC42L2; RAC1B; SPHK1; PIK3CD; CDC42
Focal adhesion
MYLK3; MAPK9; ITGB3B; FIGF; COL6A6; PPP1CAA; AKT3A; ITGB1B.2; SOS1; PARVA
Tight junction
MYH3; PRKCB; TJAP1; PARD6GB; CLDN6; CLDN2; CASKA; CLDN18; PRKCBA; MYLPFB
Gap junction
GRM5; MAP2K2A; GRB2; TUBA8L; CX35B; GNAI1; PLCB4; SOS1; TUBB1; GNAI2A
Natural killer cell mediated cytotoxicity
NCR2; KLRC2; HRAS; RAET1E; HLA-A; PIK3R3; PIK3CB; KLRC3; KLRD1; PTPN11
B cell receptor signaling pathway
IGHM; AKT1; PPP3R1; CD72; CSK; PPP3R2; VAV2; MAPK3; PIK3R1; CD19
Fc gamma R-mediated phagocytosis
INPP5D; SCIN; PIK3R2; PRKCE; FCGR3A; PLA2G4A; PIK3R5; LIMK1; RAC2; PIK3CB
Leukocyte transendothelial migration
MYL9; VCAM1; MYL12A; OCLN; MSN; GNAI3; PXN; RHOH; GNAI1; RAC1
Circadian entrainment
GNG12; GRIN2C; PRKCG; PRKCA; GNG8; KCNJ3; GRIA4; GNB2; PER2; GNAI1
Long-term potentiation
GRIN2B; RAF1; PRKACA; CALM1; CAMK2B; PPP3R1; GRIA1; CALML5; PPP3CC; GRIN2C
Retrograde endocannabinoid signaling
PRKCB; SLC17A7; GABRR3; GABRD; GABRA4; GNG3; SLC17A6; GABRP; GNB2; PRKCG
Glutamatergic synapse
PLA2G4A; PLCB1; GRIA2; PLCB4; GNG13; GRIA3; GRM4; GRM2; SLC1A1; PLA2G4D
Cholinergic synapse
AKT1; CHRNA4; GNG11; ITPR1; PRKACB; CAMK2B; CHRM1; GNG12; CREB5; KCNQ1
Serotonergic synapse
GNGT2; CYP2C39; PRKACB; HTR1F; MAPK3; HTR3B; CYP2C55; APP; ALOX8; GNB4
GABAergic synapse
PRKACA; PRKACG; SLC6A13; PRKCB; GNG11; GNG7; GABRR1; PRKACB; GABRD; GNB3
Dopaminergic synapse
DRD1A; CALY; CREB3L4; PPP2CA; CREB3L2; ATF4; GSK3B; GNGT1; GNG8; GRIN2B
Long-term depression
ITPR3; PPP1R17; CRHR1; PLCB1; LYN; KRAS; MAP2K1; PRKCG; PLA2G4D; RAF1
Inflammatory mediator regulation of TRP channels
PIK3CD; PRKCH; PRKCB; MAPK10; CYP4A14; PLA2G4F; CALM2; P2RY2; ALOX12; CYP2J2
Insulin secretion
RYR2; PDX1; PRKACB; PRKACG; KCNMB4; KCNMA1; GCG; CCKAR; CREB3L2; GPR119
GnRH signaling pathway
ADCY1B; PRKACAB; PLCB3; PRKACBB; NRAS; MAPK7; GNRH2; CDC42L2; LHBETA1; GNA15.1
Melanogenesis
CALM3; FZD8B; WNT10B; ADCY1B; DVL3A; GNAO1B; GNAI2; CALM3B; CALM2; NRAS
Thyroid hormone synthesis
ATP1A3; CANX; GPX1; CREB3L3; TTF2; PLCB2; GPX2; ITPR1; DUOX2; ATP1B1
Thyroid hormone signaling pathway
BMP4; TRP53; PIK3CD; PFKP; RCAN2; MDM2; ESR1; PIK3R3; WNT4; PLCZ1
Oxytocin signaling pathway
MAPK3; PIK3R5; CACNA2D1; MYL6; MYLK3; MYLK2; Adcy4; MYLK4; CAMK2D; CALML3
Aldosterone synthesis and secretion
CALM3; CAMK4; PDE2A; DDX1; CREB3L2; CREB3L4; NR4A2; PRKCE; HSD3B6; MC2R
Insulin resistance
PYGL; G6PCA.2; PIK3R5; PPARGC1B; INSR; AKT1; NOS3; CREB3L3A; RPS6KA2; MAPK10
Aldosterone-regulated sodium reabsorption
NEDD4L; HSD11B2; PRKCA; ATP1B4; INS2; MAPK3; PIK3CD; FXYD2; ATP1A2; ATP1B2
Endocrine and other factor-regulated calcium reabsorption
ATP1A2; PTH1R; PLCB2; PRKACA; KLK1B3; ESR1; ATP1B2; ATP1B4; PRKACB; TRPV5
Salivary secretion
PRKCA; CALML5; PRKCB; ATP1A4; CALML3; PRH1; ATP1A3; CST3; CALM1; PLCB1
Gastric acid secretion
KCNE2; ATP1A2; GAST; ITPR1; PLCB2; ITPR3; CAMK2A; CAMK2D; KCNJ16; MYLK4
Pancreatic secretion
PLA2G2F; ATP2A1; ATP1A3; PLA2G2E; CELA3B; Slc4a2; ATP1A1; ATP2A3; TRPC1; RAB3D
Carbohydrate digestion and absorption
AMY1B; HK3; G6PC; PRKCB; SLC37A4; HKDC1; ATP1B4; ATP1A4; HK1; PIK3CD
Amphetamine addiction
PRKACG; PRKCB; TH; CALM4; PRKCG; CALM1; DRD1A; GRIN1; PPP3R1; ATF2
Morphine addiction
ADORA1; PDE4C; GNG8; GABRR2; PDE8A; PRKACB; GNG4; GABRA1; PRKACA; GABRG3
Leishmaniasis
IL12A; ITGB2L; MAPK13; NFKBIA; FCGR1; NCF2; HLA-DRB4; H2-AB1; HLA-DRA; HLA-DMA
African trypanosomiasis
HPR; SELE; PLCB2; IL12B; LAMA4; PRKCA; IFNG; ICAM1; HBB; HBB-B1
Amoebiasis
COL4A1; LAMA4; ITGB2; ACTN2; PLCB3; ARG2; TNF; RELA; GM-CSF; SERPINB3
Hepatitis B
PIK3CG; IFNA17; PIK3CD; IFIH1; DDB2; IL-8; FADD; MAPK8; TGFB2; IFNA4
Influenza A
IFN-a; PYCARD; EP300; IL8L1; RAF1; TMPRSS13; HLA-DMB; NXT2; HSPA1L; IVNS1ABP
Pathways in cancer
WNT2B; GLI3; FIGF; BIRC3; PLCG1; PIK3CA; GNA11; BDKRB1; RALBP1; RALGDS
Proteoglycans in cancer
PRKACG; RHOA; CAMK2B; PIK3CG; PDPK1; RRAS; RDX; WNT7A; ITPR1; SOS1
MicroRNAs in cancer
SIRT1; VEGFA; PDCD4; NOTCH2; SERPINB5; PRKCG; MCL1; PIK3R2; TGFB2; BCL2L2
Glioma
PLCG1; CALML3; MAP2K2; PLCG2; SOS1; PIK3R3; PRKCB; AKT1; CAMK2B; KRAS
Non-small cell lung cancer
MAPK3; PLCG2; AKT1; RB1; RASSF5; EML4; PRKCA; FOXO3; PIK3CD; GRB2
Choline metabolism in cancer
WASF3; RALGDS; PPAP2B; SLC5A7; RAC1; TSC2; AKT1; PDGFA; DGKA; PIK3CG

Protein Function

PRKCB has several biochemical functions, for example, ATP binding, androgen receptor binding, calcium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKCB itself. We selected most functions PRKCB had, and list some proteins which have the same functions with PRKCB. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein UBE2D4; HSPE1; PTK2; CSNK1D; GNE; BMP2K; MKNK2; ATP5A1; DGKG; CHEK1
Function androgen receptor binding
Related Protein RNF6; RNF4; NCOA3; RB1; EP300; Ar; KDM4C; KDM3A; PIAS1; RAN
Function calcium channel regulator activity
Related Protein HPCAL4; SRI; NPY; CACNA2D2; SGK3; CACNA2D3; PRKG1; SGK1; SGK2A; GRM7
Function chromatin binding
Related Protein SP100; TAF2; ESR1; CALCOCO1; SMARCE1; NEUROD1; AJUBA; HMG20B; CAMTA2; SETD7
Function histone binding
Related Protein DAXX; RNF168; UHRF2; NCAPD2; HIST1H4F; PIH1D1; ZMYND11; APBB1; DTX3L; PHF21A
Function histone kinase activity (H3-T6 specific)
Related Protein PRKCB; PRKCBB; PRKCA
Function ligand-dependent nuclear receptor transcription coactivator activity
Related Protein MED17; MED30; NCOA3; PPRC1; RBM14; HELZ2; HMGA1-RS1; PPARGC1B; SFR1; NCOA1
Function protein binding
Related Protein MAT2B; TTLL6; DAK; INPP5B; ESYT2; AKR1B10; SLIT2; CXCR4; C14orf135; IMP3
Function protein kinase C activity
Related Protein PRKCB; PRKCBB; PRKCDA; PRKCZ; PRKCHB; PKN1; PRKCI; PRKCD; PRKD1; PRKCE
Function protein kinase C binding
Related Protein TIRAP; LDB3; GLRX3; TOP2A; GNB2L1; SDPR; HDAC7; HDAC9; YWHAG; TRPV4
Function protein serine/threonine kinase activity
Related Protein PBK; PAK3; CDC42BPG; STK32A; TTBK1; CDK12; VPRBP; SNRKA; PRPF4B; OXSR1B
Function zinc ion binding
Related Protein PHC1; FTR50; RARGB; UBR3; P2RX1; G2E3; COP1; PHF11; RNF138; ZDHHC16A

Interacting Protein

PRKCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKCB here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKCB.
TINF2; N/A; Glrb; PRL1; IKBKB; CHUK; LYN; HSP90AB1; GSK3B; GNB2L1; SHCBP1; PAG1; AKT1; TERF1; amn; bosutinib; bisindolylmaleimide iii; imatinib