prkcb
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  • Official Full Name
  • protein kinase C, beta
  • Background
  • plays a role in hexosamine biosynthesis pathway induced transcriptional regulation
  • Synonyms
  • Prkcb; protein kinase C, beta; Pkcb; Prkcb1; protein kinase C beta type; PKC-beta; protein kinase C beta I; protein kinase C beta
Cat.#:PRKCB-1953HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRKCB, GST-tagged
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Cat.#:PRKCB-399HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, GST-tagged, Active
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Cat.#:PRKCB-400HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, GST-tagged, Active
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Cat.#:PRKCB-59HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, 2-671aa, His-tagged
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Cat.#:PRKCB-60HTag:His
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, 2-673aa, His-tagged
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Cat.#:PRKCB-649HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta
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Cat.#:PRKCB-13362MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PRKCB Protein
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Cat.#:Prkcb-1430RTag:His/S
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Prkcb protein, His & S-tagged
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Cat.#:PRKCB-4677RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PRKCB Protein
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Cat.#:PRKCB-3605RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PRKCB Protein, His-tagged
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Cat.#:PRKCB-1431RTag:His/S
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit PRKCB protein, His & S-tagged
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Cat.#:PRKCB-1302HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase C, Beta, GST-tagged
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Cat.#:PRKCB-2859HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PRKCB 293 Cell Lysate
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Involved Pathway

PRKCB involved in several pathways and played different roles in them. We selected most pathways PRKCB participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
PLA2G4A; FGF7; GADD45G; CACNB4; PDGFA; STMN1B; PPM1NA; RPS6KA6; GNA12A; CACNA1SB
ErbB signaling pathway
GAB1; GSK3B; BRAF; ELK1; AREG; CAMK2B1; PRKCA; MAP2K4; NCK1; BADB
Ras signaling pathway
RGL2; RAC3; FGFR2; KLK1B4; MAPK3; PLA2G1B; FGF22; Pdgfa&Pdgfb; FGF2; PIK3R3
Rap signaling pathway
RAP1GAP; RRAS; PRKD3; PIK3CG; FGFR2; ARAP3; FGF9; LPAR5; CALM1; PRKCB
Calcium signaling pathway
P2RX3; EDNRBA; CHRM3; GNAS; SLC25A6; ERBB3A; AGTR1; PLCB3; ATP2A2B; STIM1
Chemokine signaling pathway
PAK1; GNG4; CCL11; CCL16; CCL7; SHC2; NRAS; CXCR3; CCR6; PREX1
NF-kappa B signaling pathway
MAP3K7IP3; IRAK1; NFKB2; TICAM2; RIPK1; LTBR; CXCL2; NFKB1; MAP3K14; BLNK
HIF- signaling pathway
ENO3; ANGPT2; VEGFA; HIF1A; TCEB1; Trf; Il6ra; EIF4E2; IGF1; PDHA1
Phosphatidylinositol signaling system
PIK3CD; PIP5K1BA; MTMR14; PIK3CG; PI4KB; TMEM55A; PLCG2; PLCD1A; IPMKB; ITPKB
Sphingolipid signaling pathway
NSMAF; LASS2; ABCC1; PIK3R5; AKT1; PRKCG; PPP2R5B; TNFRSF1A; RHOA; PLD1
mTOR signaling pathway
PTENA; PRKAA2; IRS1; PIK3CB; RPS6KAL; PIK3R3A; RRAGCA; RPS6KA2; RPS6KA3B; PIK3R3
Vascular smooth muscle contraction
PLA2G5; RAF1A; MAP2K1; PLA2G6; PPP1R14AB; ADCY2B; PRKCBB; MYLK4; MYLK3; KCNMB2
Wnt signaling pathway
PRKACBA; PRKACAB; PRKCBA; PRKACAA; DAAM1B; BTRC; PRICKLE1A; TCF7L1A; Fzd4; RAC3
VEGF signaling pathway
CDC42L2; MAPKAPK2A; HRASA; PRKCBB; PTGS2B; PTK2; RAC1; PLCG1; AKT1; PTK2AB
Focal adhesion
PPP1R12C; ITGA7; PTENA; MYL7; AKT2L; HRASA; CCND2A; PIK3R3A; ITGA2; GSK3AA
Tight junction
AKT2L; AKT3A; PPP2R2A; CLDN23; PRKCG; EPB41L3A; SPTAN1; JAM3B; CLDN22; MYH6
Gap junction
PRKCG; HTR2CL1; GNA11; MAP2K2; Pdgfa&Pdgfb; MAPK7; PRKACBB; TUBA8L3; GNA11A; PDGFA
Natural killer cell mediated cytotoxicity
IFNA6; RAC2; SAMD3; IFNA2; IFNA21; ARAF; MAPK1; FCGR3B; PIK3R1; KIR2DL4
B cell receptor signaling pathway
DAPP1; CD72; KRAS; PDPK1A; FOS; LILRB3; CD79B; NFKBIE; PIK3CD; ARPC5
Fc gamma R-mediated phagocytosis
RAC1; MAPK3; RAF1; AKT1; GAB2; PPAP2B; RAC2; ASAP2; PIK3CD; ARPC1A
Leukocyte transendothelial migration
RHOA; CLDN17; MAPK12; NIPAL1; CLDN2; CXCL12; AASS; MYL10; ROCK2; CLDN4
Circadian entrainment
GNG4; GNAO1; ITPR3; GNG5; RPS6KA5; CALM3; GNAS; PER3; GNG11; GNB2
Long-term potentiation
RPS6KA1; GRIN2B; PLCB2; PLCB1; ITPR3; CAMK4; CAMK2A; GRM1; PPP1R1A; RPS6KA6
Retrograde endocannabinoid signaling
GABRG3; GABRG2; MAPK12; PRKCB; PRKCA; GABRA1; GABRB2; GNB1; MAPK10; GNB4
Glutamatergic synapse
PRKACB; PRKACA; SLC1A2; PPP3CB; GNG3; GNAI2; PLCB1; SLC38A3; GRIN2C; SLC38A1
Cholinergic synapse
CREB3L1; GNAI3; CREB3L2; KCNQ4; KCNQ5; CAMK2B; PLCB4; CHRNA7; CAMK4; CHRNA4
Serotonergic synapse
GNG5; HTR1F; GNG10; TRPC1; PLCB3; PRKACB; RAF1; GNAO1; CYP4X1; MAP2K1
GABAergic synapse
GABARAPL2; GABRG2; GLS; GNG12; GNG2; PRKCG; GABRG3; GNGT1; GAD2; GNG3
Dopaminergic synapse
DRD2; PPP2R3C; ATF6B; GNG3; PRKCG; SLC6A3; DRD5; CREB3L2; PPP2R5E; KIF5A
Long-term depression
ITPR3; GNAQ; KRAS; RYR1; GNAI2; GNA13; GRM1; GNA11; MAP2K1; GNAZ
Inflammatory mediator regulation of TRP channels
MAPK8; PLA2G6; CYP2C50; PTGER2; IGF1; PIK3CA; CALM3; PPP1CA; ACCN4; CYP4A14
Insulin secretion
SLC2A1; PDX1; PRKACG; ATP1A1; RAPGEF4; INS1; ATP1B3; Adcy4; ATP1B2; CREB3L2
GnRH signaling pathway
CAMK2B; CDC42L2; CALM4; MAPK12B; MAPK8A; GNA15.4; GNRH1; MAP2K4A; PTK2B; CACNA1C
Melanogenesis
MAPK1; FZD8; Fzd4; CAMK2D; WNT2BB; FZD10; FZD5; EDNRB2; TCF7L1A; WNT8A
Thyroid hormone synthesis
PRKCB; PRKACA; CREB3L3; TSHB; LRP2; PLCB2; IYD; ASGR2; ATP1B3; PLCB4
Thyroid hormone signaling pathway
WNT4; SLC9A1; HRAS; ATP2A2; PLCE1; TRP53; PIK3R1; ATP1A4; ACTG1; PLCG2
Oxytocin signaling pathway
PPP3CC; CALM1; CACNG4; GNAI3; GNAQ; RCAN1; MYLK2; ROCK2; CACNB3; CACNG7
Aldosterone synthesis and secretion
Adcy4; ATF1; ATF4; ADCY6; AGTR1; CALML3; GNAQ; AKR1C1; ADCY1; ATF2
Insulin resistance
PPP1R3CA; IRS2; PYGB; PTPN11A; PPP1CA; PIK3R3A; RELA; SLC27A4; PPARAB; CREB3L3
Aldosterone-regulated sodium reabsorption
PRKCA; PIK3CD; NR3C2; SCNN1B; ATP1B3; SLC9A3R2; PIK3CG; HSD11B2; KCNJ1; ALPHA-ENAC
Endocrine and other factor-regulated calcium reabsorption
PRKACA; KLK1B9; PRKCA; GNAS; CALB1; ATP1B4; KLK1B11; BDKRB2; PLCB1; GNAQ
Salivary secretion
ATP1B2; ATP1B4; GUCY1B3; ITPR1; ATP2B4; LYZ2; PRKACG; CD38; PRKG1; CALM4
Gastric acid secretion
PRKCB; MYLK2; KCNJ16; KCNE2; MYLK4; Adcy4; CAMK2A; ATP1A2; ITPR3; CCKBR
Pancreatic secretion
SLC9A1; RYR2; CLCA2; CELA3B; SLC4A4; PLCB4; PLCB3; PLA2G5; AMY2A4; ATP1B2
Carbohydrate digestion and absorption
AMY2A4; AMY2B; ATP1A3; PIK3R3; PIK3CD; PRKCB; HK2; PIK3CG; AMY2A; AMY2A5
Amphetamine addiction
GRIA1; CREB3L3; PDYN; PPP1CA; GRIN2D; CAMK2G; CAMK2B; PPP3R2; FOSB; CREB3L4
Morphine addiction
PDE8B; GNAS; GABBR1; GNB4; ADORA1; GRK4; PDE3A; GNG12; GABRD; GABRA3
Leishmaniasis
HLA-DRB4; PTPN6; TGFB2; FCGR4; HLA-DPB1; FOS; TGFB1; MAPK3; IRAK4; HLA-DQB1
African trypanosomiasis
IFNG; Fasl; TLR9; APOA1; PRKCB; SELE; PRKCA; IDO1; PLCB2; HBB-B2
Amoebiasis
LAMA5; COL4A3; LAMB2; TLR4; TGFB2; COL3A1; ITGAM; COL1A1; IL1R2; COL5A1
Hepatitis B
PTK2B; NFATC2; CCNE2; FOS; BAX; CCNA1; Fasl; BAD; TNF; DDX58
Influenza A
CCL5; NUP98; GSK3B; IFNA2; IFIH1; MAPK1; DDX39B; IFNA4; RNASEL; MAP2K2
Pathways in cancer
WNT8B; RXRB; FH; GNA11; IKBKB; APC2; CKS2; CASP8; LPAR6; GSTP1
Proteoglycans in cancer
PPP1R12B; PTPN6; PRKACA; IGF2; MDM2; DROSHA; FZD5; PLAU; ITGB3; RAF1
MicroRNAs in cancer
MAPK1; WNT3A; UBE2I; ERBB3; RHOA; ERBB2; BMPR2; SLC7A1; NOTCH3; MMP9
Glioma
CAMK2D; MAPK1; MAP2K2; NRAS; PTEN; CAMK2A; PIK3R5; TGFA; PRKCB; IGF1
Non-small cell lung cancer
BAD; ARAF; MAP2K2; PLCG2; PIK3R1; PIK3R5; MAPK3; PRKCA; FOXO3; PIK3CD
Choline metabolism in cancer
RALGDS; MAPK10; MAPK9; PIK3CD; PDGFC; PIK3R1; SLC22A2; RAF1; AKT1; PIK3R5

Protein Function

PRKCB has several biochemical functions, for example, ATP binding, androgen receptor binding, calcium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKCB itself. We selected most functions PRKCB had, and list some proteins which have the same functions with PRKCB. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein DDX59; ABCF3; CHD4A; PIP4K2C; MYH9; MCM8; ABCB9; MSH4; NSF; MCMDC2
Function androgen receptor binding
Related Protein KDM1A; KDM4C; PRPF6; EP300; NRIP1; RAN; PRKCBB; RNF14; TCF21; CALR
Function calcium channel regulator activity
Related Protein GRM6A; SGK2A; TSPAN13; TMEM110; TSPAN13A; GRM7; PRKCB; NPY2R; Crisp4; NRXN3
Function chromatin binding
Related Protein SMC1A; ATF2; ERG; PYGO2; EP300; PKN1; HIF1AB; CITED1; BARX2; FOXN4
Function histone binding
Related Protein NFKBIL2; JAK2; Ctsl; PHF21B; NASP; PKN1; HIST1H4I; HIST1H4C; BRD7; NCL
Function histone kinase activity (H3-T6 specific)
Related Protein PRKCBB; PRKCA; PRKCB
Function ligand-dependent nuclear receptor transcription coactivator activity
Related Protein AASS; MED17; PSMC3IP; PPARGC1B; MED30; PRKCBB; LRP2BP; SFR1; NCOA2; SLC30A9
Function protein binding
Related Protein CHMP1A; LGALS1; CENPI; TSC22D4; TTC12; ANXA6; TREML1; MARK3; TLE3A; CORO1B
Function protein kinase C activity
Related Protein PRKCHB; PRKCBB; PRKCQ; PKN1; PRKCD; PRKD3; PRKCH; PRKCI; PRKCBA; PKN3
Function protein kinase C binding
Related Protein SDC4; IRS1; HDAC7A; HDAC7; UGT1A7; ADAM9; HSPB1; PARD3; DACT1; C1QBP
Function protein serine/threonine kinase activity
Related Protein CDK1; SGK2B; CSNK1A1L; CSNK1G2B; PRKCA; PKMYT1; DYRK4; MAP4K2; LMTK2; STK31
Function zinc ion binding
Related Protein RBX1; ADAM10; ZFAND1; MMP12; FHL1B; CPD; RBM5; ADAMTS2; RECQL4; SYVN1

Interacting Protein

PRKCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKCB here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKCB.
TINF2; N/A; Glrb; PRL1; IKBKB; CHUK; LYN; HSP90AB1; GSK3B; GNB2L1; SHCBP1; PAG1; AKT1; TERF1; amn; bosutinib; bisindolylmaleimide iii; imatinib