Prss2 Protein, protease, serine, 2 (trypsin 2)

Prss2

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Prss2

Official Full Name protease, serine, 2 (trypsin 2)
Background Trypsinogen is the precursor form or zymogen of the pancreatic enzyme trypsin. It is found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen. It is activated by enteropeptidase, which is found in the intestinal mucosa, to form trypsin. Once activated, the trypsin can activate more trypsinogen into trypsin. Trypsin cleaves peptide bond on carboxyl side of basic amino acids. Serum trypsinogen is measured using a blood test. High levels are seen in acute pancreatitis, and cystic fibrosis.
Synonyms PRSS2 protease, serine, 2; PRSS2; TRYP; 8 anionic trypsin; pancreatic anionic trypsinogen; NP_777115.1; EC 3.4.21.4; Trypsinogen
    • Species :
    • Bovine
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Yeast
    • Tag :
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Rat PRSS2-2690R Recombinant Rat PRSS2 Protein (24-246 aa), His-tagged Yeast His
    Human PRSS2-316H Recombinant Human Protease, Serine, 2 (Trypsin 2) , His-tagged HEK293 His
    Human PRSS2-7091H Recombinant Human PRSS2 protein, His & T7-tagged E.coli His/T7
    Human PRSS2-850H Recombinant Human PRSS2 E.coli N/A
    Mouse PRSS2-2293MCL Recombinant Mouse PRSS2 cell lysate Human Cell N/A
    Mouse Prss2-7092M Recombinant Mouse Prss2 protein, His-tagged E.coli His
    Mouse Prss2-909M Recombinant Mouse Prss2, His tagged Human Cell His
    Rat PRSS2-4739R Recombinant Rat PRSS2 Protein Mammalian Cell His
    Rhesus Macaque PRSS2-3637R Recombinant Rhesus monkey PRSS2 Protein, His-tagged Mammalian Cell His
    Bovine PRSS2-6B Recombinant Bovine Trypsin N/A
    Chicken PRSS2-6936C Recombinant Chicken PRSS2 Mammalian Cell His

    Prss2 involved in several pathways and played different roles in them. We selected most pathways Prss2 participated on our site, such as Neuroactive ligand-receptor interaction, Pancreatic secretion, Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with Prss2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction P2RX4A; HTR7; PRLR; TAAR14A; TAAR8A; BDKRB1; ADORA2AB; TAAR2; GRIN2D; P2RX1
    Pancreatic secretion LOC780933; SLC26A3; PLA2G2A; AMY2A; PLCB1; PNLIPRP1; ATP1A2; CPA3; PRSS3; AMY2A4
    Protein digestion and absorption CELA2B; KCNE3; XPNPEP2; KCNQ1; SLC8A1; PGA4; COL10A1; CELA3B; CELA3A; FXYD2
    Influenza A MAPK9; KPNA1; FASLG; MAPK1; HSPA1B; AKT2; IL12A; ACTG1; OAS1A; RELA

    Prss2 has several biochemical functions, for example, calcium ion binding, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Prss2 itself. We selected most functions Prss2 had, and list some proteins which have the same functions with Prss2. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding GM5077; SWAP70B; PCDHB14; PCDHB10; EPS15; KCNIP3A; CALML5; CALB1; CDH6; PCDHA2
    protein binding SMIM3; CCDC153; PEBP1; AMBP; DIEXF; LEO1; SNRPD2; ZFYVE16; HGD; MUS81
    serine-type endopeptidase activity KLK1B3; KLK1B16; PROC; F10; KLK1; PLG; F7; CELA2A; CTRC; PCSK5

    Prss2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Prss2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Prss2.

    Lin, JJ; Zhao, DM; et al. Transcriptome changes upon in vitro challenge with Mycobacterium bovis in monocyte-derived macrophages from bovine tuberculosis-infected and healthy cows. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 163:146-156(2015).
    Mounzer, R; Whitcomb, DC; et al. Genetics of acute and chronic pancreatitis. CURRENT OPINION IN GASTROENTEROLOGY 29:544-551(2013).

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