|Official Full Name||protease, serine, 2 (trypsin 2)|
|Background||Trypsinogen is the precursor form or zymogen of the pancreatic enzyme trypsin. It is found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen. It is activated by enteropeptidase, which is found in the intestinal mucosa, to form trypsin. Once activated, the trypsin can activate more trypsinogen into trypsin. Trypsin cleaves peptide bond on carboxyl side of basic amino acids. Serum trypsinogen is measured using a blood test. High levels are seen in acute pancreatitis, and cystic fibrosis.|
|Synonyms||PRSS2 protease, serine, 2; PRSS2; TRYP; 8 anionic trypsin; pancreatic anionic trypsinogen; NP_777115.1; EC 220.127.116.11; Trypsinogen|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
Prss2 involved in several pathways and played different roles in them. We selected most pathways Prss2 participated on our site, such as Neuroactive ligand-receptor interaction, Pancreatic secretion, Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with Prss2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Neuroactive ligand-receptor interaction||P2RX4A; HTR7; PRLR; TAAR14A; TAAR8A; BDKRB1; ADORA2AB; TAAR2; GRIN2D; P2RX1|
|Pancreatic secretion||LOC780933; SLC26A3; PLA2G2A; AMY2A; PLCB1; PNLIPRP1; ATP1A2; CPA3; PRSS3; AMY2A4|
|Protein digestion and absorption||CELA2B; KCNE3; XPNPEP2; KCNQ1; SLC8A1; PGA4; COL10A1; CELA3B; CELA3A; FXYD2|
|Influenza A||MAPK9; KPNA1; FASLG; MAPK1; HSPA1B; AKT2; IL12A; ACTG1; OAS1A; RELA|
Prss2 has several biochemical functions, for example, calcium ion binding, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Prss2 itself. We selected most functions Prss2 had, and list some proteins which have the same functions with Prss2. You can find most of the proteins on our site.
|calcium ion binding||GM5077; SWAP70B; PCDHB14; PCDHB10; EPS15; KCNIP3A; CALML5; CALB1; CDH6; PCDHA2|
|protein binding||SMIM3; CCDC153; PEBP1; AMBP; DIEXF; LEO1; SNRPD2; ZFYVE16; HGD; MUS81|
|serine-type endopeptidase activity||KLK1B3; KLK1B16; PROC; F10; KLK1; PLG; F7; CELA2A; CTRC; PCSK5|
Prss2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Prss2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Prss2.