rab10
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  • Official Full Name
  • RAB10, member RAS oncogene family
  • Background
  • RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and;endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 (PubMed 9918381)).
  • Synonyms
  • RAB10; RAB10, member RAS oncogene family; ras-related protein Rab-10; ras related GTP binding protein; GTP-binding protein RAB10; ras-related GTP-binding protein
Cat.#:RAB10-2974HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB10, T7-tagged
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Cat.#:RAB10-31037THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB10, T7 -tagged
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Cat.#:RAB10-7263HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAB10, His-tagged
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Cat.#:RAB10-13780MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RAB10 Protein
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Cat.#:RAB10-8694MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse RAB10 Protein, His-tagged
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Cat.#:RAB10-2771CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RAB10
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Cat.#:RAB10-687ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RAB10
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Cat.#:RAB10-2632HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RAB10 293 Cell Lysate
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Involved Pathway

RAB10 involved in several pathways and played different roles in them. We selected most pathways RAB10 participated on our site, such as AMPK signaling pathway, Endocytosis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB10 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
AMPK signaling pathway
RAB8A; RAB14; INS1; PPP2CB; FBP2; AKT1S1; AKT2; CREB3L3; STRADA; CAMKK1
Endocytosis
KITA; D6WSU116E; CDC42L; EPN2; RLN1; SH3GL1A; ARPC4L; ZFYVE9; PSD4; CAV3
Membrane Trafficking
PREB; MCFD2; GJD3; STXBP3; PICALMB; TRAPPC6BL; SNAPIN; TRAPPC9; CLINT1; GJB3
Translocation of GLUT4 to the plasma membrane
RALAA; RALAB; MYO1C; STXBP3; RAB10
Vesicle-mediated transport
PLDN; GJD3; GJB7; SNF8; CX30.3; NAPG; CPD; TRAPPC6A; ARCN1; BLOC1S3

Protein Function

RAB10 has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB10 itself. We selected most functions RAB10 had, and list some proteins which have the same functions with RAB10. You can find most of the proteins on our site.
Function
Related Protein
Function GDP binding
Related Protein RAB4A; RAP2B; RAB28; RAB31; PRPS2; EIF2B1; RAB7A; RAB7; RALB; TRIM23
Function GTP binding
Related Protein EHD3; RHOBTB2; RAB33BA; RAB3B; ARL5B; GIMAP4; DIRAS1A; RAB39BB; AGAP2; RAB22A
Function GTPase activity
Related Protein TUBG2; EEF1A1; RAN; GBP2; OPA1; RASL10A; ARL4D; GNAT1; RAB2B; MRAS
Function myosin V binding
Related Protein RAB14; RAB11B; RAB39B; RAB3D; RAB27A; RAB6B; RAB3B; RAB6A; RAB25; RAB10
Function protein binding
Related Protein FAM154A; AGTRAP; SGOL1; HDAC10; TFDP1; LGALS3; ZHX1; PALM; FCER2; KIAA0141

Interacting Protein

RAB10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB10 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB10.
OPTN; ganglioside_gm1; 7242199; AURKA; DOK2; EPB41; RAB8A; AP1S1; MFSD1; TRAF6; q5nfa1_fratt; MICALL1; SBBI23; ENOPH1; UL36; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

RAB10 Related Articles

Hoffmann, C; Finsel, I; et al. Functional analysis of novel Rab GTPases identified in the proteome of purified Legionella-containing vacuoles from macrophages. CELLULAR MICROBIOLOGY 16:1034-1052(2014).
Babbey, CM; Bacallao, RL; et al. Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 299:F495-F506(2010).