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RAB10

  • Official Full Name

    RAB10, member RAS oncogene family

  • Overview

    RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and;endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 (PubMed 9918381)).
  • Synonyms

    RAB10; RAB10, member RAS oncogene family; ras-related protein Rab-10; ras related GTP binding protein; GTP-binding protein RAB10; ras-related GTP-binding protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • Myc
  • DDK
  • Flag
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RAB10-31037TH Recombinant Human RAB10, T7 -tagged E.coli T7
Human RAB10-7263H Recombinant Human RAB10, His-tagged E.coli His 1-200aa
Human RAB10-2632HCL Recombinant Human RAB10 293 Cell Lysate HEK293 N/A
Human RAB10-119HFL Recombinant Full Length Human RAB10 Protein, C-Flag-tagged Mammalian cells Flag
Human RAB10-2974H Recombinant Human RAB10, T7-tagged E.coli T7
Human RAB10-1823H Recombinant Human RAB10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human RAB10-7264H Recombinant Human RAB10 protein, His-tagged E.coli His Partial
Human RAB10-005H Recombinant Human RAB10 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human RAB10-2776H Recombinant Human RAB10 protein, His-tagged E.coli His 130-200 aa
Human RAB10-7265H Recombinant Human RAB10 protein, His&Myc-tagged Insect Cell His&Myc 1-200aa
Human RAB10-1823H-B Recombinant Human RAB10 Protein Pre-coupled Magnetic Beads HEK293
Mouse RAB10-8694M Recombinant Mouse RAB10 protein, His-tagged E.coli His 1-200aa
Mouse RAB10-13780M Recombinant Mouse RAB10 Protein Mammalian Cell His
Mouse Rab10-3399M Recombinant Mouse Rab10 protein, His-SUMO-tagged E.coli His-SUMO 1-200aa
Mouse Rab10-5282M Recombinant Mouse Rab10 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse RAB10-7335M Recombinant Mouse RAB10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RAB10-7335M-B Recombinant Mouse RAB10 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish RAB10-687Z Recombinant Zebrafish RAB10 Mammalian Cell His
Chicken RAB10-2771C Recombinant Chicken RAB10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RAB10 Related Articles

RAB10 involved in several pathways and played different roles in them. We selected most pathways RAB10 participated on our site, such as AMPK signaling pathway, Endocytosis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AMPK signaling pathwayPIK3CA;PPP2R5B;AKT1S1;PPP2R5A;EEF2K;FASN;INSR;ADRa1A;HNF4A
EndocytosisSH3GL2;SMAD3A;ZFP652;CLTCB;RHOA;SPG21;PIP5K1A;CDC42L2;HSP70L
Membrane TraffickingRAB10;CNIH2;SNX9;MIA3;TERFA;STXBP3;ARCN1B;YKT6;TGOLN2
Translocation of GLUT4 to the plasma membraneRALAA;STXBP3;MYO1C;RAB10;RALAB
Vesicle-mediated transportAP3S1;TPD52;GJA5;DTNBP1B;ARCN1A;NAPB;GAK;SNF8;TRAPPC6B

RAB10 has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB10 itself. We selected most functions RAB10 had, and list some proteins which have the same functions with RAB10. You can find most of the proteins on our site.

Function Related Protein
GDP bindingEIF2B1;SEPT12;RAB27B;RAB5C;RAB31;RAP2B;RAB35;RAB18;RAB9A
GTP bindingAK3;RAB37;RAB6C;NPR2;ACSM5;RAB40AL;NME1;RAB35B;IRGC
GTPase activityDDX3X;RAB40AL;RND1;RAB32;MFN1;RAB44;GBP2;ARL1;EEF1A1L2
myosin V bindingRAB6B;RAB10;RAB27A;RAB8A;RAB3C;RAB27B;RAB14;RAB39B;FUS
protein bindingPDIA4;PCGF3;TLN1;TMEM59;IFIT1;GPC3;HDAC7A;TMEM106C;AKR7A3

RAB10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB10 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB10.

OPTN; ganglioside_gm1; 7242199; AURKA; DOK2; EPB41; RAB8A; AP1S1; MFSD1; TRAF6; q5nfa1_fratt; MICALL1; SBBI23; ENOPH1; UL36; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

Hoffmann, C; Finsel, I; et al. Functional analysis of novel Rab GTPases identified in the proteome of purified Legionella-containing vacuoles from macrophages. CELLULAR MICROBIOLOGY 16:1034-1052(2014).
Babbey, CM; Bacallao, RL; et al. Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 299:F495-F506(2010).
  • Q&As
  • Reviews

Q&As (8)

Ask a question
Did you check the phosphorylation status of the produced protein? 02/13/2023

We didn't check the phosphorylation status of our RAB10 proteins. But the following one expressed in HEK293 should be phosphorylated.

How does RAB10 contribute to the process of autophagy and cellular homeostasis? 08/12/2022

RAB10 aids in autophagy, maintaining cellular health by regulating the degradation and recycling of cell components.

What role does RAB10 play in insulin-stimulated glucose uptake and metabolic regulation? 01/27/2021

RAB10 plays a crucial role in glucose uptake and metabolism, particularly in response to insulin.

What are the mechanisms by which RAB10 modulates cell signaling and communication? 10/03/2020

RAB10 regulates cell signaling pathways, playing a role in intercellular communication and response to stimuli.

How does RAB10 influence the development and progression of neurodegenerative diseases? 05/12/2020

RAB10 is linked to neurodegenerative diseases, potentially influencing protein aggregation and neuronal function.

How do alterations in RAB10 expression or activity affect the pathogenesis of diabetes and insulin resistance? 05/04/2019

Variations in RAB10 can contribute to the development of diabetes and insulin resistance by affecting glucose metabolism.

How does RAB10 (Ras-Related Protein Rab-10) facilitate intracellular vesicle trafficking and membrane transport? 01/02/2019

RAB10 is key in directing vesicle trafficking, ensuring efficient transport and membrane dynamics within cells.

What is the impact of RAB10 on endocytic pathways and receptor recycling? 08/07/2018

RAB10 impacts endocytosis and receptor trafficking, affecting cell surface receptor dynamics and signaling.

Customer Reviews (3)

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Reviews
04/12/2021

    Reliable mass spectrometry analysis, pivotal for advancing our proteomics research.

    07/07/2019

      Accurate protein structural analysis, indispensable for our investigations.

      10/17/2018

        Swift and reliable protein sequencing, a key asset for our work.

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