raet1e
Share
  • Official Full Name
  • retinoic acid early transcript 1E
  • Background
  • This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • RAET1E; retinoic acid early transcript 1E; NKG2D ligand 4; bA350J20.7; LETAL; ULBP4; Lymphocyte effector toxicity activation ligand; MGC125308; MGC125309; N2DL-4; N2DL4; NKG2D ligand 4 precursor; NKG2DL4; RAE-1-like transcript 4; RAET1E2; RL-4; OTTHUMP00000017403; OTTHUMP00000017404; OTTHUMP00000229731
Cat.#:RAET1E-206HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human RAET1E Protein, His-tagged
+Inquiry
Cat.#:RAET1E-209HTag:His|HIgG
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human RAET1E Protein, hIgG-His-tagged
+Inquiry
Cat.#:RAET1E-381HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human retinoic acid early transcript 1E, His-tagged
+Inquiry
Cat.#:RAET1E-764HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human RAET1E Protein, Fc-tagged
+Inquiry
Cat.#:RAET1E-765HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human RAET1E Protein, His-tagged
+Inquiry
Cat.#:RAET1E-2549HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human RAET1E 293 Cell Lysate
+Inquiry

Involved Pathway

RAET1E involved in several pathways and played different roles in them. We selected most pathways RAET1E participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAET1E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
UBE2V1; EVL; SIGLEC11; AP1S3A; IFI30; CD300LH; DCTN2; RNF138; ASB10; HUWE1
Immune System
ABI1A; CSH1; DEFA1; KIF15; SH2D1B; KIF5B; OASL; UBR1; CD96; SIGLEC14
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
MICA; Mill2; CRTAM; OSCAR; SIGLEC10; CD300LB; LILRA1; SLAMF6; CD160; LILRB1
Natural killer cell mediated cytotoxicity
PTK2B; ITGB2L; IFNA2; PIK3CG; KIR2DS3; SAMD3; ULBP3; HLA-E; PRKCG; FCGR3

Protein Function

RAET1E has several biochemical functions, for example, natural killer cell lectin-like receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAET1E itself. We selected most functions RAET1E had, and list some proteins which have the same functions with RAET1E. You can find most of the proteins on our site.
Function
Related Protein
Function natural killer cell lectin-like receptor binding
Related Protein CLEC2H; RAET1E; RAET1L; RAET1G; H60a; HLA-E; ULBP2; SAMD3; MICA; Raet1c

RAET1E Related Articles

Cho, H; Chung, JY; et al. MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer. BMC CANCER 14:-(2014).
Cox, ST; Laza-Briviesca, R; et al. Further polymorphism of the RAET1E/ULBP4 gene in humans. TISSUE ANTIGENS 84:435-437(2014).