rgs4
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  • Official Full Name
  • regulator of G-protein signaling 4
  • Background
  • Regulators of G protein signaling (RGS) are a family of about 40 proteins that determine the signaling amplitude and duration of G protein-coupled receptor signaling via modulation of the GTPase activity of G proteins. Each RGS has a distinct structure, e
  • Synonyms
  • RGS4; regulator of G-protein signaling 4; regulator of G protein signalling 4 , schizophrenia disorder 9 , SCZD9; schizophrenia disorder 9; RGP4; SCZD9; MGC2124; MGC60244; DKFZp761F1924
Cat.#:RGS4-3616HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGS4, His-tagged
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Cat.#:RGS4-1563HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Regulator Of G-protein Signaling 4, His-tagged
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Cat.#:RGS4-29969THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGS4
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Cat.#:RGS4-14145MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RGS4 Protein
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Cat.#:RGS4-5020RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RGS4 Protein
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Cat.#:RGS4-5955CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RGS4
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Cat.#:RGS4-9906ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RGS4
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Cat.#:RGS4-2372HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RGS4 293 Cell Lysate
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Involved Pathway

RGS4 involved in several pathways and played different roles in them. We selected most pathways RGS4 participated on our site, such as Calcium Regulation in the Cardiac Cell, G alpha (i) signalling events, G alpha (z) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium Regulation in the Cardiac Cell
GJC1; PKIB; GJA4; KCNJ3; CHRM1; YWHAQ; RGS5B; RGS4; AKR1C1; RGS17
G alpha (i) signalling events
PENKB; RGS20; OXGR1A.3; RLN3; OPN1MW; CNR1; ANXA1; CCL35.1; ANXA1A; PYYA
G alpha (z) signalling events
RGS20; ADRA2B; RGS4; ADRA2A; RGS17; RGS19; ADRA2C
GPCR downstream signaling
TRPC3; ARHGEF25; RGS7; OPN1MW; RAMP2; GPBAR1; OPN4.1; NPSR1; GPR55A; APLN
Myometrial Relaxation and Contraction Pathways
IGFBP2; CNN2; RAMP2; GABPA; CRCP; PKIG; RGS16; GPR182; IGFBP4; CRH
Signal Transduction
RHOV; ARHGAP26; GPR77; AMOTL2; SST; MYO9B; EVL; CRABP2B; FAM13A; BCO2L
Signaling by GPCR
EMR4; UTS2D; PROK1; ARHGEF25; KISS1; ARHGEF17; ACKR4; PROKR1A; RGS14; OR2AP1

Protein Function

RGS4 has several biochemical functions, for example, G-protein alpha-subunit binding, GTPase activator activity, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS4 itself. We selected most functions RGS4 had, and list some proteins which have the same functions with RGS4. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein alpha-subunit binding
Related Protein DRD1A; RIC8A; HTR2B; F2R; PPP5C; CRHR1; RIC8B; F2RL1; RIC8; RGS19
Function GTPase activator activity
Related Protein ARHGEF12; ASAP3; GMIP; AGFG1B; RALGAPA2; ARHGAP27; FAM13B1; ARHGAP17; LLGL2; RASAL2
Function calmodulin binding
Related Protein KCNQ3; KCNN1B; CDK5RAP2; CNN1A; MYH1; MYLK2; RGS16; MYO5C; PLA2G6; MYO6

Interacting Protein

RGS4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS4.
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RGS4 Related Articles

Calipari, ES; Sun, HG; et al. Amphetamine Self-Administration Attenuates Dopamine D2 Autoreceptor Function. NEUROPSYCHOPHARMACOLOGY 39:1833-1842(2014).
Shirley, MD; Tang, H; et al. Sturge-Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ. NEW ENGLAND JOURNAL OF MEDICINE 368:1971-1979(2013).