RNF2 Protein, ring finger protein 2


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Official Full Name ring finger protein 2
Background The polycomb group (PcG) proteins contribute to the maintenance of cell identity, stem cell self-renewal, cell-cycle regulation, and oncogenesis by maintaining the silenced state of genes that promote cell lineage specification, cell death, and cell-cycle
Synonyms RNF2; ring finger protein 2; E3 ubiquitin-protein ligase RING2; BAP 1; BAP1; DING; HIPI3; RING1B; RING2; protein DinG; RING finger protein 1B; RING finger protein BAP-1; HIP2-interacting protein 3; huntingtin-interacting protein 2-interacting protein 3; B
    • Species :
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNF2-158H Recombinant Human RNF2 protein, T7/His-tagged E.coli T7/His
    Human RNF2-2284HCL Recombinant Human RNF2 293 Cell Lysate HEK293 N/A
    Human RNF2-2341H Recombinant Human RNF2, GST-tagged E.coli GST
    Human RNF2-695H Recombinant Human RNF2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Rat RNF2-5080R Recombinant Rat RNF2 Protein Mammalian Cell His
    Zebrafish RNF2-8814Z Recombinant Zebrafish RNF2 Mammalian Cell His

    RNF2 involved in several pathways and played different roles in them. We selected most pathways RNF2 participated on our site, such as Cellular Senescence, Cellular responses to stress, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular Senescence CBX8B; PHC2; EP400; MINK1; SUZ12A; HIST1H1A; E2F3; AGO1; HIRA; CDKN2B
    Cellular responses to stress RBB4L; CDKN2B; CDKN2A; PHC3; HMGA1-RS1; CEBPB; HIF1AL; ATG7; HIST1H1B; HIRA
    Metabolism of proteins DDOST; ARSK; TOMM22; SPON2; FXC1; TOMM7; ARSI; ARSD; ADAMTSL5; TRAPPC6BL
    Oxidative Stress Induced Senescence SUZ12A; MINK1; RNF2; SUZ12B; RING1; CBX6A; CBX8A; EED; BMI1A; CBX8
    Post-translational protein modification SPON2; ADAMTS4; PPP6R3; DHPS; TMED2; NSMCE2; PPP6C; SAE1; ADAMTSL1; ARSD
    SUMO E3 ligases SUMOylate target proteins SMC5; NSMCE1; SMC6; PHC3; NSMCE2; PHC2; CBX8; NSMCE4A; PHC1; SCMH1
    SUMOylation of DNA damage response and repair proteins NSMCE1; EID3; PHC1; CBX8; NSMCE4A; SMC6; PHC2; NSMCE2; SCMH1; PHC3

    RNF2 has several biochemical functions, for example, RING-like zinc finger domain binding, chromatin binding, ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF2 itself. We selected most functions RNF2 had, and list some proteins which have the same functions with RNF2. You can find most of the proteins on our site.

    Function Related Protein
    RING-like zinc finger domain binding RNF2; UBE2I; BMI1
    chromatin binding ZEB1; TOP1; HMGXB4A; NSBP1; POLA1; NR5A1A; TOX; RUNX2; FEZF2; JUN
    ligase activity PIAS4; C12orf51; ACSF2; RNF138; RNF168; HLTF; TTLL11; TNFAIP3; RNF185; UBE2L3B
    protein binding ZMYM4; NRAP; NGB; MSX2; SERPINA1A; MOXD1; DERL3; GATA1; UBE2R2; NR4A3
    ubiquitin protein ligase activity FBXL22; RNF6; BTRC; RNF13; FBXO30; SYVN1; C18orf25; UBE2KA; TRAF6; RAG2
    contributes_to ubiquitin-protein transferase activity KLHL31; RNF20; KLHL2; KLHL9; KLHL20; KBTBD12; FBXW8; KLHL3; KLHL28; DTL
    zinc ion binding ZNF146; ADH5; PCGF1; RNF169; MYRIP; TRIM26; RFWD3; RNF138; RXRA; PCGF2

    RNF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF2.

    BMI1; CBX8; PCGF2

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