RNF4 Protein, ring finger protein 4


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Official Full Name ring finger protein 4
Synonyms RNF4;ring finger protein 4;SLX5;SNURF;RES4-26;E3 ubiquitin-protein ligase RNF4;E3 ubiquitin ligase RNF4;small nuclear RING finger protein;EC=6.3.2;Protein SNURF;002938;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNF4-314H Recombinant Human RNF4 Protein, GST-tagged E.coli GST
    Human RNF4-2276HCL Recombinant Human RNF4 293 Cell Lysate HEK293 N/A
    Human RNF4-7193H Recombinant Human Ring Finger Protein 4, His-tagged E.coli His
    Mouse RNF4-14347M Recombinant Mouse RNF4 Protein Mammalian Cell His
    Mouse Rnf4-1654M Recombinant Mouse Rnf4 protein, His & GST-tagged E.coli His/GST
    Rat RNF4-5083R Recombinant Rat RNF4 Protein Mammalian Cell His
    Chicken RNF4-2104C Recombinant Chicken RNF4 Mammalian Cell His

    RNF4 involved in several pathways and played different roles in them. We selected most pathways RNF4 participated on our site, such as Adaptive Immune System, Androgen receptor signaling pathway, Antigen processing: Ubiquitination &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System LRRC41; CD300E; ITGB1B.1; CDKN1A; ASB9; CD200R2; CLTC; KIF5B; CRTAM; GM11711
    Androgen receptor signaling pathway EFCAB6; POU2F1B; NCOA2; PSMC3IP; RNF4; STUB1; KAT7B; JUN; RUNX2A; CTNNB1
    Antigen processing: Ubiquitination &amp UBE2F; TRIM9; UBA5; LRSAM1; LRRC41; RNF220; RNF6; ASB11; TRIM50; FBXO27
    Proteasome degradation ARIH2; KLHL20; CMTM2A; UBA5; ASB13; TRIM50; UBE2E3; ASB10; HECTD3; STUB1
    Class I MHC mediated antigen processing &amp UBR2; RNF4; RNF144B; SEC23A; UBA5; UBR1; UFL1; TRAF7; UBE2U; FCGR1B
    presentation SPSB4; KLHL21; TRIM11; CD207; STUB1; LTN1; FBXO44; BLMH; RNF34; DZIP3
    DNA Repair EYA2; RNF111; RAD1; USP45; PARP1; FAM175A; PPIE; USP10; CHEK1; TCEA1
    HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) WRN; BRE; RAD1; RAD9B; TP53BP1; PPP4CB; RAD9; EME1; BABAM1; RTEL1
    Homology Directed Repair PPP4R2A; KIAA0146; PPP4CB; EME2; FUZ; GEN1; PPP4R2; PPP4R2B; RAD51AP1; EME1

    RNF4 has several biochemical functions, for example, DNA binding, SUMO polymer binding, androgen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF4 itself. We selected most functions RNF4 had, and list some proteins which have the same functions with RNF4. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ZNF521; HMGB1B; SMYD1; OLIG1; HIST1H2AN; DLX5A; SCML4; HES1; TRIM28; NKX2-6
    SUMO polymer binding RNF222; RNF111; SIMC1; SOBP; RNF4
    androgen receptor binding CTNNB1; PIAS1; TRIM68; PRKCBB; PRMT2; RNF14; GRIP1; PIAS2; KDM4C; RNF4
    identical protein binding CD74; USP2; GAPDH; CLDN14; SERPINA1D; TRP53; SCUBE1; SERPINA1A; SERPINA1; TRIM21
    ligase activity PRP19; SIAH1A; DTX1; RNF13; RNF20; UBOX5; ITCHA; RNF180; WWP2; TRIM13
    nucleosome binding MUM1; SMARCA5; HP1BP3; ZNHIT1; RNF169; NOC2L; RNF4; L3MBTL1; RNF168; DNTTIP1
    protein binding KCTD9; ZNF155; PYCRL; RPL36AL; CSNK2B; TRIM22; LIG4; ZNF524; LRRK2; RAB24
    transcription coactivator activity RB1; MYOD1; GTF2A1L; BRDT; RFXAP; MED23; USP22; ACTL6B; RNF14; ABRA
    transcription factor activity, sequence-specific DNA binding HOXC4; ZNF311; ETV5A; FOXN4; POU3F2; VDRB; PLAG1; CLOCKB; CNBP; ZNF726
    transcription factor binding SP1; FOXA2; TAF7; PPID; HES3; HTT; TRP53; NLK; PSMD4; ID1
    ubiquitin protein ligase activity UBE2R2; HECW1B; AMFR; MARCH1; FLJ11011L; ZSWIM2; UBE2J2; RNF152; SYVN1; UBE2U
    ubiquitin-protein transferase activity BRCA1; FBXO21; TRIM24; TSPAN17; PRKCQ; RNF141; ZYG11B; MALT1; SHPRH; FBXO30A
    zinc ion binding LIMK2; KMT2E; ZFP385C; LHX8; MIB1; THRA; LHX2; RABGEF1L; HNF4G; ADAM8A

    RNF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF4.


    Hendriks, IA; Treffers, LW; et al. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. CELL REPORTS 10:1778-1791(2015).
    Pagadala, NS; Perez-Pineiro, R; et al. In silico studies and fluorescence binding assays of potential anti-prion compounds reveal an important binding site for prion inhibition from PrPC to PrPSc. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 91:118-131(2015).

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