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Recombinant Mouse Rnf4 protein, His & GST-tagged

Cat.No. : Rnf4-1654M
Product Overview : Recombinant Mouse Rnf4 aa. (Met1~Ile194 (Accession # Q9QZS2)) fused with N-terminal His & GST tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Description : This gene encodes a small nuclear RING finger protein that mediates ubiquitylation of polysumoylated proteins. Deficiency of the encoded protein in mice leads to embryonic lethality and global DNA hypermethylation. A similar protein in humans is required for arsenic-induced degradation of promyelocytic leukemia protein in acute promyelocytic leukemia. Alternative splicing of this gene results in multiple transcript variants. A pseudogene for this gene has been identified on chromosome 10.
Source : E. coli
Species : Mouse
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 51.9kDa
Protein length : Met1~Ile194 (Accession # Q9QZS2)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >90%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Isoelectric Point : 7.6
Gene Name : Rnf4 ring finger protein 4 [ Mus musculus (house mouse) ]
Official Symbol : Rnf4
Synonyms : Rnf4; ring finger protein 4; SNURF; Gtrgeo8; AU018689; E3 ubiquitin-protein ligase RNF4; E3 ubiquitin ligase RNF4; RING-type E3 ubiquitin transferase RNF4
Gene ID : 19822
mRNA Refseq : NM_001304269.1
Protein Refseq : NP_001291198.1
UniProt ID : Q9QZS2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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