Recombinant Human RNF4 Protein, GST-tagged

• Cat.No.: RNF4-314H
• Product Overview: Recombinant Human RNF4 Protein is produced by Bacteria expression system. This protein is fused with a GST tag.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: RING-finger 4 (RNF4), also known as Snurf, is an E3 ubiquitin ligase. RNF4 is composed of four SUMO interaction motifs (SIMs) at the N-terminal and a RING domain at the C-terminal. The SIM domains prefer binding polySUMO chains; RNF4 functions to ubiquitinate polysumolyated proteins including promyelocytic leukaemia (PML), which target them for proteasomal degradation.
• Form: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
• Molecular Mass: 21.3 kDa
• Purity: > 90 % by SDS-PAGE
• Storage: Store at -80 centigrade; avoid multiple freeze-thaw cycles.

Gene Information

• Gene Name: RNF4 ring finger protein 4 ( Homo sapiens (human) )
• Official Symbol: RNF4
• Synonyms: SLX5; SNURF; RES4-26
• Gene ID: 6047
• mRNA Refseq: NM_001185009
• Protein Refseq: NP_001171938
• MIM: 602850
• UniProt ID: D3DVQ6