SIGLEC9 Protein, sialic acid binding Ig-like lectin 9

SIGLEC9

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SIGLEC9

Official Full Name sialic acid binding Ig-like lectin 9
Background Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Synonyms SIGLEC9; sialic acid binding Ig-like lectin 9; sialic acid-binding Ig-like lectin 9; CD329; protein FOAP-9; CDw329; FOAP-9; siglec-9; OBBP-LIKE
    • Species :
    • Human
    • Rhesus monkey
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Tag :
    • Fc
    • GST
    • hIgG1
    • hIgG4
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SIGLEC9-1844HCL Recombinant Human SIGLEC9 293 Cell Lysate HEK293 N/A
    Human SIGLEC9-2671H Recombinant Human SIGLEC9, GST-tagged E.coli GST
    Human SIGLEC9-676H Recombinant Human SIGLEC9, Fc-tagged, Biotinylated Human Cell Fc
    Human SIGLEC9-677H Recombinant Human SIGLEC9 protein, Fc-tagged HEK293 human/IgG1/Fc
    Rhesus monkey SIGLEC9-1749R Recombinant Rhesus Monkey SIGLEC9 Protein HEK293 N/A
    Rhesus monkey SIGLEC9-1750R Recombinant Rhesus Monkey SIGLEC9 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey SIGLEC9-1751R Recombinant Rhesus Monkey SIGLEC9 Protein, hIgG4-tagged HEK293 hIgG4

    SIGLEC9 involved in several pathways and played different roles in them. We selected most pathways SIGLEC9 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIGLEC9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System MICA; TRIM39; AP2A2; UBA5; DCTN2; HCST; ASB6; ASB17; CTSD; FRS2A
    Immune System CASPB; IFIT10; TRIM69; ADAR; IGHM; CISH; DYNLL2; ASB8; RIPK3; LILRB3
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell CD160; CD300E; TREML4; CD200R2; KLRB1A; LILRB3; ICAM4; CD226; Siglece; LILRA3

    SIGLEC9 has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIGLEC9 itself. We selected most functions SIGLEC9 had, and list some proteins which have the same functions with SIGLEC9. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding SIGLEC8; GALM; MAN2B2; PVRL1; Il2; CLEC7A; ZP3; CHI3L1; ZG16; CD248

    SIGLEC9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIGLEC9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIGLEC9.

    Kardava, L; Moir, S; et al. Attenuation of HIV-associated human B cell exhaustion by siRNA down regulation of inhibitory receptors. JOURNAL OF CLINICAL INVESTIGATION 121:2614-2624(2011).
    Biesen, R; Demir, C; et al. Sialic acid-binding Ig-like lectin I expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus. ARTHRITIS AND RHEUMATISM 58:1136-1145(2008).

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