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SIGLEC9

  • Official Full Name

    sialic acid binding Ig-like lectin 9

  • Overview

    Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
  • Synonyms

    SIGLEC9; sialic acid binding Ig-like lectin 9; sialic acid-binding Ig-like lectin 9; CD329; protein FOAP-9; CDw329; FOAP-9; siglec-9; OBBP-LIKE;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Human
  • Rhesus monkey
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian cells
  • C
  • Fc
  • Flag
  • GST
  • hIgG1
  • hIgG4
  • His
  • His (Fc)
  • Avi
  • human|IgG1|Fc
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SIGLEC9-676H Active Recombinant Human SIGLEC9, Fc-tagged, Biotinylated Human Cell Fc
Human SIGLEC9-2671H Recombinant Human SIGLEC9, GST-tagged E.coli GST 210-340aa
Human SIGLEC9-677H Recombinant Human SIGLEC9 protein, Fc-tagged HEK293 human/IgG1/Fc Gln18-Gly348
Human SIGLEC9-1844HCL Recombinant Human SIGLEC9 293 Cell Lysate HEK293 N/A
Human SIGLEC9-145H Recombinant Human SIGLEC9(Gln19-Leu353) Protein, C-6*His-tagged HEK293 His
Human SIGLEC9-6068H Recombinant Human SIGLEC9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SIGLEC9-051H Recombinant Human SIGLEC9 Protein, His-tagged E.coli His
Human SIGLEC9-146H Recombinant Human SIGLEC9 protein, His-Avi-tagged HEK293 His-Avi It contains Gln18-Gly348.
Human SIGLEC9-2690H Recombinant Human SIGLEC9 Protein, His-tagged E.coli N-His Gln18-Thr346
Human SIGLEC9-963HFL Recombinant Full Length Human SIGLEC9 Protein, C-Flag-tagged Mammalian cells Flag
Human SIGLEC9-0734H Active Recombinant Human SIGLEC9 protein, Fc-tagged HEK293 Fc Gln18-Gly348
Human SIGLEC9-1414H Recombinant Human SIGLEC9 Protein (Met25-Leu142), N-His tagged E.coli N-His Met25-Leu142
Human SIGLEC9-0732H Recombinant Human SIGLEC9 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln18-Gly348
Human SIGLEC9-2012H Recombinant Human SIGLEC9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SIGLEC9-0735H Active Recombinant Human SIGLEC9 protein, His-tagged HEK293 His Gln18-Gly348
Human SIGLEC9-2012H-B Recombinant Human SIGLEC9 Protein Pre-coupled Magnetic Beads HEK293
Human SIGLEC9-4197H Recombinant Human SIGLEC9 Protein (Gln18-Gly348), C-Fc tagged Mammalian cells C-Fc Gln18-Gly348
Rhesus monkey SIGLEC9-1749R Recombinant Rhesus Monkey SIGLEC9 Protein HEK293 N/A
Rhesus monkey SIGLEC9-1750R Recombinant Rhesus Monkey SIGLEC9 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey SIGLEC9-1751R Recombinant Rhesus Monkey SIGLEC9 Protein, hIgG4-tagged HEK293 hIgG4
Cynomolgus SIGLEC9-0733C Active Recombinant Cynomolgus SIGLEC9 protein, His-tagged HEK293 His Gln20-Gly350
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SIGLEC9 Related Articles
  • SIGLEC9 Related Research Area

SIGLEC9 involved in several pathways and played different roles in them. We selected most pathways SIGLEC9 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIGLEC9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemTHEM4;GRAP2B;SH2D1B;UBE2E3;MAPKAP1;CSK;CTS7;AP2S1;SIGLEC8
Immune SystemTRIM46;SEC24A;EIF4G2A;NLRP3;CD200R3;UBA5;ERAP2;ASB18;KIF2A
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellTREML1;NCR3LG1;CD300E;LILRA1;KLRB1B;Siglece;CD300C;LILRA3;CD300LH

SIGLEC9 has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIGLEC9 itself. We selected most functions SIGLEC9 had, and list some proteins which have the same functions with SIGLEC9. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingPKD1L3;LGALS2B;CD55;PRPS1;CLEC2H;SORD;PRG3;CNTN1;ZG16

SIGLEC9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIGLEC9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIGLEC9.

Kardava, L; Moir, S; et al. Attenuation of HIV-associated human B cell exhaustion by siRNA down regulation of inhibitory receptors. JOURNAL OF CLINICAL INVESTIGATION 121:2614-2624(2011).
Biesen, R; Demir, C; et al. Sialic acid-binding Ig-like lectin I expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus. ARTHRITIS AND RHEUMATISM 58:1136-1145(2008).
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