sik2
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  • Official Full Name
  • salt-inducible kinase 2
  • Background
  • SIK2 (Salt inducible kinase 2) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and AMP-activated protein kinase (AMPK) subfamily, predicted molecular weight 104 kD. SIK2 is found in adipocytes and might be involved in metabo
  • Synonyms
  • SIK2; salt-inducible kinase 2; SNF1 like kinase 2 , SNF1LK2; serine/threonine-protein kinase SIK2; DKFZp434K1115; KIAA0781; LOH11CR1I; QIK; SIK-2; SNF1-like kinase 2; qin-induced kinase; salt-inducible protein kinase 2; salt-inducible serine/threonine kin
Cat.#:SIK2-1954HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SIK2 protein, His & T7-tagged
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Cat.#:SIK2-30089THTag:
Source (Host):Species:Human
Product nameRecombinant Human SIK2
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Cat.#:SIK2-415HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Salt-inducible Kinase 2, GST-tagged, Active
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Cat.#:Sik2-1955MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Sik2 protein, His & T7-tagged
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Cat.#:SIK2-1478HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human QIK (Active), GST-tagged
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Cat.#:SIK2-1841HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SIK2 293 Cell Lysate
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Involved Pathway

SIK2 involved in several pathways and played different roles in them. We selected most pathways SIK2 participated on our site, such as Glucagon signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIK2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glucagon signaling pathway
PRKAB2; PHKA2; G6PC; PHKB; PFKL; AKT1; PRKAA1; CAMK2B; PLCB3; ACACA

Protein Function

SIK2 has several biochemical functions, for example, ATP binding, magnesium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIK2 itself. We selected most functions SIK2 had, and list some proteins which have the same functions with SIK2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein KIF18B; MYO6B; GSG2; ACTR1; GPHN; ASS1; ABCB8; STRADB; LONP1; KIF12
Function magnesium ion binding
Related Protein PI4K2A; EYA2; ENO1A; NUDT5; PPA1B; PGM3; MAP2K7; ABL1; ITPK1A; ADSS
Function protein binding
Related Protein FST; TSGA10; CCL5; CLEC1B; O3far1; HLA-DRB3; MIEN1; YY1AP1; NCOA3; CASP14
Function protein serine/threonine kinase activity
Related Protein TRIO; TGFBR1B; SRPK1; MASTL; PASK; IRAK2; PBK; SMOK3B; MAPK1; AURKA

Interacting Protein

SIK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIK2.
CEP250; GABARAPL2; PPP2R2B; linkable pd173955 analogue; bosutinib; imatinib; dasatinib; midostaurin; BAG2; HSPB1; PPP2R1B; FUS