SLC3A2

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SLC3A2

Official Full Name solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Background This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
Synonyms 4F2; CD98; MDU1; 4F2HC; 4T2HC; NACAE; CD98HC; SLC3A2; 4F2 cell-surface antigen heavy chain; heavy chain; CD98 heavy chain; OTTHUMP00000082735; OTTHUMP00000236708; OTTHUMP00000236709; OTTHUMP00000236712; OTTHUMP00000238367; 4F2 heavy chain antigen Monoclonal 44D7; lymphocyte activation antigen 4F2 large subunit; antigen defined by Monoclonal 4F2, heavy chain; antigen identified by Monoclonal antibodies 4F2, TRA1.10, TROP4, and T43
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • HlgG1 Fc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Rat SLC3A2-949R Recombinant Rat SLC3A2 Protein (Ala100-Ala527), HlgG1 Fc-tagged HEK293 HlgG1 Fc
    Human SLC3A2-2015HCL Recombinant Human SLC3A2 cell lysate Human Cell N/A
    Human SLC3A2-229H Recombinant Human SLC3A2 Protein, His-tagged Insect Cell His
    Human SLC3A2-26956TH Recombinant Human SLC3A2 Wheat Germ N/A
    Human SLC3A2-2768H Recombinant Human SLC3A2, His-tagged E.coli His
    Human SLC3A2-3960H Recombinant Human SLC3A2 protein, His-tagged HEK293 His
    Human SLC3A2-587H Recombinant Human SLC3A2, Fc-tagged, Biotinylated Human Cell Fc
    Human SLC3A2-588H Recombinant Human SLC3A2, Fc-tagged Human Cell Fc
    Mouse Slc3a2-1196M Recombinant Mouse Slc3a2 protein, His & GST-tagged E.coli His/GST
    Mouse SLC3A2-1772MCL Recombinant Mouse SLC3A2 cell lysate Human Cell N/A
    Mouse Slc3a2-7031M Recombinant Mouse Slc3a2, His tagged Human Cell His
    Rat Slc3a2-1197R Recombinant Rat Slc3a2 protein, His & GST-tagged E.coli His/GST
    Rat SLC3A2-1199RCL Recombinant Rat SLC3A2 cell lysate Human Cell N/A
    Rat SLC3A2-5538R Recombinant Rat SLC3A2 Protein Mammalian Cell His
    Rat Slc3a2-8781R Recombinant Rat Slc3a2, His tagged Human Cell GST

    SLC3A2 involved in several pathways and played different roles in them. We selected most pathways SLC3A2 participated on our site, such as Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC3A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein digestion and absorption CPA2; CELA2A; CPB1; ACE2; ATP1B1; CPA1; CPA3; PGA4; PRSS3; COL4A1

    SLC3A2 has several biochemical functions, for example, calcium:sodium antiporter activity, catalytic activity, cation binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC3A2 itself. We selected most functions SLC3A2 had, and list some proteins which have the same functions with SLC3A2. You can find most of the proteins on our site.

    Function Related Protein
    calcium:sodium antiporter activity SLC8A1B; SLC8A2; SLC8A1; SLC8A2A; SLC8A2B; SLC8A1A; SLC24A4; SLC8A4B; SLC8A4A; SLC24A6
    catalytic activity PNP5B; SYN2B; ACSL1A; ALP3; BLM; PPM1DB; ALDOAB; AOX3L1; PPTC7A; GAD1B
    cation binding PPM1DA; PPM1LA; GBE1; PPM1AB; SLC3A2; PPM1AA; PPM1NB; Amy1; PPM1BA; SLC3A2B
    double-stranded RNA binding DROSHA; TARBP2; HSPD1; DICER1; CLTC; HSP90AB1; OASL; OASL1; LSM14A; DHX36
    neutral amino acid transmembrane transporter activity SLC1A5; SLC43A1B; SLC3A2; SLC43A2; SLC43A2A; SLC38A5; SLC43A1A; SLC43A2B; SLC7A8; SLC15A1B
    poly(A) RNA binding HNRNPH3; EIF1B; EIF3I; PIGC; RBM4B; SNTB2; GNL3; RBM39; RPS23; TFB1M
    protein binding SH3RF1; H2AFX; UBE2V2; TLN1; A2M; RNF135; DRAM1; RDBP; LGALS1; SAP30L

    SLC3A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC3A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC3A2.

    EGFR; PTP4A3; ARF6; TSC22D1; PHB2; BRF2; NEK6; GSTK1; PHLDA3; b3xyc5_sollc; 15-deoxy-delta(12,14; ere_dna; FN1; cona_canen

    El-Mallawany, NK; Day, N; et al. Differential proteomic analysis of endemic and sporadic Epstein-Barr virus-positive and negative Burkitt lymphoma. EUROPEAN JOURNAL OF CANCER 51:92-100(2015).
    Estrach, S; Lee, SA; et al. CD98hc (SLC3A2) Loss Protects Against Ras-Driven Tumorigenesis by Modulating Integrin-Mediated Mechanotransduction. CANCER RESEARCH 74:6878-6889(2014).

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