stk10
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  • Official Full Name
  • serine/threonine kinase 10
  • Background
  • This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
  • Synonyms
  • STK10; serine/threonine kinase 10; serine/threonine-protein kinase 10; LOK; PRO2729; lymphocyte-oriented kinase
Cat.#:STK10-2966HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human STK10 Protein, MYC/DDK-tagged
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Cat.#:STK10-343HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Serine/Threonine Kinase 10, GST-tagged, Active
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Cat.#:STK10-555HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Serine/Threonine Kinase 10, His-tagged
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Cat.#:STK10-765HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STK10, His tagged
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Cat.#:STK10-11354ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish STK10
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Cat.#:STK10-1711HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human STK10 cell lysate
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Protein Function

STK10 has several biochemical functions, for example, ATP binding, identical protein binding, polo kinase kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by STK10 itself. We selected most functions STK10 had, and list some proteins which have the same functions with STK10. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CDK13; IPPK; CHD9; IRAK4; CASK; HSP104; P2RX1; MAP3K9; TNIKA; FES
Function identical protein binding
Related Protein CREBZF; GRB2; ZNF703; RALYL; RYR2; SKP2; DVL1; CLDN6; BLOC1S6; C14orf166
Function polo kinase kinase activity
Related Protein STK10
Function protein binding
Related Protein SUZ12; SLMAP; RIN3; AZIN2; PIAS1; MPZL2; CSNK1G2; NTM; PSMD10; ZNF165
Function protein homodimerization activity
Related Protein OSTA; XPNPEP1; SIAH1A; ERP29; BCL2A1; RRAGA; GPD1A; BNIP3L; RCHY1; ECT2
Function protein serine/threonine kinase activity
Related Protein MAPK1; PLK3; GM7168; DAPK1; TGFBR1A; MAP4K3; SLKA; BRAF; PRKCQ; GRK1B

Interacting Protein

STK10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STK10 here. Most of them are supplied by our site. Hope this information will be useful for your research of STK10.
abl-tide; midostaurin