Active Recombinant Full Length Human STK10 Protein, GST tagged

• Cat.No.: STK10-1121H
• Product Overview: Recombinant full-length human LOK was expressed in Sf9 cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Insect cells
• Tag: GST
• Protein Length: 1-968 aa
• Description: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
• Molecular Mass: ~138 kDa
• Bio-activity: 1.0 nmol/min/mg
• Purity: >85%
• Stability: 1 year at -70 centigrade from date of shipment.
• Storage: Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Concentration: 0.1 μg/μL
• Shipping: Dry Ice
• Reference: 1. Kuramochi S, et al., 1997, J. Biol. Chem. 272 (36): 22679-84. 2. Kuramochi S, et al., 1999, Immunogenetics. 49 (5): 369-75. 3. Walter, SA. et al., J Biol Chem 2003, 278 (20):18221-8.

Gene Information

• Gene Name: STK10 serine/threonine kinase 10 [ Homo sapiens (human) ]
• Official Symbol: STK10
• Synonyms: STK10; serine/threonine kinase 10; LOK; PRO2729; serine/threonine-protein kinase 10; lymphocyte-oriented kinase; EC 2.7.11.1
• Gene ID: 6793
• mRNA Refseq: NM_005990
• Protein Refseq: NP_005981
• MIM: 603919
• UniProt ID: Q9UIW4