thbd
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  • Official Full Name
  • thrombomodulin
  • Background
  • Thrombomodulin (TM) is a transmembrane glycoprotein composed of 575 amino acids (molecular weight 75 kD with natural anticoagulant properties ( Wen et al, 1987 ). It is normally expressed by a restricted number of cells, such as endothelial and mesothelia
  • Synonyms
  • THBD; thrombomodulin; CD141; fetomodulin; CD141 antigen; TM; THRM; AHUS6; BDCA3; THPH12
Cat.#:THBD-2601HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Thrombomodulin
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Cat.#:THBD-2743HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human THBD protein, His-tagged
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Cat.#:THBD-2744HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human THBD protein, His & T7-tagged
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Cat.#:THBD-31177THTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human THBD protein
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Cat.#:THBD-31179THTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human THBD
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Cat.#:THBD-3217HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human THBD, His-tagged
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Cat.#:THBD-16735MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse THBD Protein
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Cat.#:Thbd-2745MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Thbd protein, His-tagged
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Cat.#:Thbd-2746RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Thbd protein, His-tagged
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Cat.#:Thbd-2747RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Thbd protein, His-tagged
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Cat.#:Thbd-8787RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat THBD, His tagged
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Cat.#:THBD-4697RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey THBD Protein, His-tagged
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Cat.#:THBD-2742DTag:His|GST
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog THBD protein, His & GST-tagged
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Cat.#:THBD-2602HTag:His
Source (Host):NS0Species:
Product nameRecombinant Human Thrombomodulin, His-tagged
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Cat.#:THBD-306RTag:N/A
Source (Host):Species:Rabbit
Product nameNative Rabbit Lung Thrombomodulin
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Cat.#:THBD-1220RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat THBD cell lysate
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Involved Pathway

THBD involved in several pathways and played different roles in them. We selected most pathways THBD participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with THBD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Complement and coagulation cascades
F12; F2; SERPINA1; VWF; F13B; MBL2; F3; CFD; THBD; MASP2

Protein Function

THBD has several biochemical functions, for example, calcium ion binding, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by THBD itself. We selected most functions THBD had, and list some proteins which have the same functions with THBD. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein STIM1; CMLC1; S100A7A; ACTN3B; AIF1L; FBN1; SYT7B; PLCZ1; FKBP7; CANT1A
Function protein binding
Related Protein UVRAG; PMEPA1; MKRN1; MPLKIP; E2F8; PIH1D3; UBE2V2; ALG2; SIRT2; RASSF2
Function receptor activity
Related Protein DARC; CCR6; NOTCH1; ITGB4; SELS; TNFRSF13B; CUL5; CD244; Siglece; ABP1
Function transmembrane signaling receptor activity
Related Protein CR2; TNFRSF11A; OR2A4; NRXN2; IL4R.1; LILRB5; CD72; GHRHR2; THBD; CALCRLA

Interacting Protein

THBD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with THBD here. Most of them are supplied by our site. Hope this information will be useful for your research of THBD.
F2; mdtB; dadA; PSENEN

THBD Related Articles

Szarvas, N; Szilagyi, A; et al. First-line therapy in atypical hemolytic uremic syndrome: consideration on infants with a poor prognosis. ITALIAN JOURNAL OF PEDIATRICS 40:-(2014).
Sinibaldi, S; Guzzo, I; et al. Post-transplant recurrence of atypical hemolytic uremic syndrome in a patient with thrombomodulin mutation. PEDIATRIC TRANSPLANTATION 17:E177-E181(2013).