Recombinant Human THBD Protein, His-tagged

• Cat.No.: THBD-423H
• Product Overview: Recombinant Human THBD Protein (Ala19-Ala509) with N-His tag was expressed in 293F.

Specification

• Description: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
• Source: HEK293F
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 53.2 kDa
  Accurate Molecular Mass: 85 kDa
• Protein length: Ala19-Ala509
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: THBD thrombomodulin [ Homo sapiens (human) ]
• Official Symbol: THBD
• Synonyms: THBD; thrombomodulin; TM; THRM; AHUS6; BDCA3; CD141; BDCA-3; THPH12; thrombomodulin; CD141 antigen; fetomodulin
• Gene ID: 7056
• mRNA Refseq: NM_000361
• Protein Refseq: NP_000352
• MIM: 188040
• UniProt ID: P07204