Recombinant Human THBD Protein, His-tagged

• Cat.No.: THBD-921H
• Product Overview: Recombinant protein of the extracellular domain(A19-S515) of human thrombomodulin(THBD)(NM_000361.3), with a polyhistidine tag, was expressed in mammalian cells.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: His
• Protein Length: A19-S515
• Description: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
• Form: Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
• Molecular Mass: 55 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: THBD thrombomodulin [ Homo sapiens ]
• Official Symbol: THBD
• Synonyms: THBD; thrombomodulin; CD141; fetomodulin; CD141 antigen; TM; THRM; AHUS6; BDCA3; THPH12
• Gene ID: 7056
• mRNA Refseq: NM_000361
• Protein Refseq: NP_000352
• MIM: 188040
• UniProt ID: P07204