tmsb4x
Share
  • Official Full Name
  • thymosin beta 4, X-linked
  • Background
  • Thymosin beta-4 is a protein that in humans is encoded by the TMSB4X gene. The protein consists (in humans) of 44 amino acids (msdkpdmaei ekfdksklkk tetqeknplp sketieqekq ages) molWt 4921. This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. Thymosin beta-4 was shown to be essential for all aspects of coronary vessel development in mice; it stimulates significant outgrowth from quiescent adult epicardial explants, restoring pluripotency and triggering differentiation of fibroblasts, smooth muscle cells, and endothelial cells
  • Synonyms
  • TMSB4X; FX; PTMB4; TB4X; TMSB4; thymosin beta 4, X-linked; OTTHUMP00000022927; prothymosin beta-4; thymosin, beta 4, X chromosome; thymosin beta-4; T beta-4; THYB4; Thymosin Beat 4
Cat.#:TMSB4X-891HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TMSB4X Protein
+Inquiry
Cat.#:TMSB4X-30407THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human TMSB4X
+Inquiry
Cat.#:TMSB4X-3310HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TMSB4X, GST-tagged
+Inquiry
Cat.#:TMSB4X-653HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TMSB4X
+Inquiry
Cat.#:TMSB4X-7168HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TMSB4X protein, His-tagged
+Inquiry
Cat.#:TMSB4X-17131MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TMSB4X Protein
+Inquiry
Cat.#:Tmsb4x-7169MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tmsb4x protein, His-tagged
+Inquiry
Cat.#:TMSB4X-6189RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TMSB4X Protein
+Inquiry
Cat.#:Tmsb4x-7170RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Tmsb4x protein, His-tagged
+Inquiry
Cat.#:TMSB4X-4855RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TMSB4X Protein, His-tagged
+Inquiry
Cat.#:TMSB4X-1095CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TMSB4X
+Inquiry
Cat.#:TMSB4X-7128ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TMSB4X
+Inquiry
Cat.#:TMSB4X-7167HTag:His
Source (Host):E. coliSpecies:Horse
Product nameRecombinant Horse TMSB4X protein, His-tagged
+Inquiry
Cat.#:TMSB4X-904HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TMSB4X 293 Cell Lysate
+Inquiry

Involved Pathway

TMSB4X involved in several pathways and played different roles in them. We selected most pathways TMSB4X participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMSB4X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Regulation of actin cytoskeleton
PIP5K1AA; FGD3; MSNA; CD14; HRASA; ITGAX; RHOA; WASL; PPP1CAB; MYL12.1

Protein Function

TMSB4X has several biochemical functions, for example, actin monomer binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMSB4X itself. We selected most functions TMSB4X had, and list some proteins which have the same functions with TMSB4X. You can find most of the proteins on our site.
Function
Related Protein
Function actin monomer binding
Related Protein TMSB4X; TMSB4Y; ABL2; PFN4; CORO1A; MYL2; MTSS1; MYL4; PKNOX2; COBLL1
Function poly(A) RNA binding
Related Protein RPS2; PTCD1; MOV10; GTPBP10; DDX27; FAM98A; THRAP3; EIF4H; RPS27A; KIAA0020
Function protein binding
Related Protein PPP3R1; ARHGAP44; ELAVL2; PRKCQ; HAND1; PPP1R12C; CYCS; HELZ2; PLEC; ZSCAN16

Interacting Protein

TMSB4X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMSB4X here. Most of them are supplied by our site. Hope this information will be useful for your research of TMSB4X.
MLH1; SCHIP1; TK1; TP53; ANXA7

TMSB4X Related Articles

Yang, XR; Koltes, JE; et al. Gene Co-Expression Network Analysis Provides Novel Insights into Myostatin Regulation at Three Different Mouse Developmental Timepoints. PLOS ONE 10:-(2015).
Lan, X; Li, DM; et al. Identification of differentially expressed genes related to metabolic syndrome induced with high-fat diet in E3 rats. EXPERIMENTAL BIOLOGY AND MEDICINE 240:235-241(2015).