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TMSB4X

  • Official Full Name

    thymosin beta 4, X-linked

  • Overview

    Thymosin beta-4 is a protein that in humans is encoded by the TMSB4X gene. The protein consists (in humans) of 44 amino acids (msdkpdmaei ekfdksklkk tetqeknplp sketieqekq ages) molWt 4921. This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. Thymosin beta-4 was shown to be essential for all aspects of coronary vessel development in mice; it stimulates significant outgrowth from quiescent adult epicardial explants, restoring pluripotency and triggering differentiation of fibroblasts, smooth muscle cells, and endothelial cells
  • Synonyms

    TMSB4X; FX; PTMB4; TB4X; TMSB4; thymosin beta 4, X-linked; OTTHUMP00000022927; prothymosin beta-4; thymosin, beta 4, X chromosome; thymosin beta-4; T beta-4; THYB4; Thymosin Beat 4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Horse
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293F
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TMSB4X-30407TH Recombinant Human TMSB4X Wheat Germ N/A 44 amino acids
Human TMSB4X-3310H Recombinant Human TMSB4X, GST-tagged E.coli GST 1-63aa
Human TMSB4X-653H Recombinant Human TMSB4X protein E.coli N/A 43
Human TMSB4X-7168H Recombinant Human TMSB4X protein, His-tagged E.coli His Met1~Ser44
Human TMSB4X-904HCL Recombinant Human TMSB4X 293 Cell Lysate HEK293 N/A
Human TMSB4X-051T Active Recombinant Human TMSB4X Protein (43 aa) E.coli 43
Human TMSB4X-3391H Recombinant Human TMSB4X protein, His-SUMO-tagged E.coli His-SUMO Met1~Ser44
Human TMSB4X-431H Recombinant Human TMSB4X Protein, His-tagged HEK293F N-His Ser2-Ser44
Human TMSB4X-891H Recombinant Human TMSB4X Protein E.coli N/A
Human TMSB4X-3598H Recombinant Human TMSB4X Protein (Met1-Ser44), His tagged E.coli His Met1-Ser44
Human TMSB4X-525HF Recombinant Full Length Human TMSB4X Protein In Vitro Cell Free System 44 amino acids
Human TMSB4X-915HFL Recombinant Full Length Human TMSB4X Protein, C-Flag-tagged Mammalian cells Flag
Human TMSB4X-2215H Recombinant Human TMSB4X Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TMSB4X-2215H-B Recombinant Human TMSB4X Protein Pre-coupled Magnetic Beads HEK293
Mouse TMSB4X-17131M Recombinant Mouse TMSB4X Protein Mammalian Cell His
Mouse Tmsb4x-7169M Recombinant Mouse Tmsb4x protein, His-tagged E.coli His Met1~Ser44
Mouse TMSB4X-9459M-B Recombinant Mouse TMSB4X Protein Pre-coupled Magnetic Beads HEK293
Mouse TMSB4X-9459M Recombinant Mouse TMSB4X Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tmsb4x-6531M Recombinant Mouse Tmsb4x Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat TMSB4X-6189R Recombinant Rat TMSB4X Protein Mammalian Cell His
Rat Tmsb4x-7170R Recombinant Rat Tmsb4x protein, His-tagged E.coli His Met1~Ser44
Rat TMSB4X-5846R Recombinant Rat TMSB4X Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TMSB4X-5846R-B Recombinant Rat TMSB4X Protein Pre-coupled Magnetic Beads HEK293
Horse TMSB4X-7167H Recombinant Horse TMSB4X protein, His-tagged E.coli His Met1~Ser44 (Accession # P62327)
Rhesus Macaque TMSB4X-4855R Recombinant Rhesus monkey TMSB4X Protein, His-tagged Mammalian Cell His
Rhesus Macaque TMSB4X-4669R-B Recombinant Rhesus Macaque TMSB4X Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TMSB4X-4669R Recombinant Rhesus Macaque TMSB4X Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TMSB4X-7128Z Recombinant Zebrafish TMSB4X Mammalian Cell His
Chicken TMSB4X-1095C Recombinant Chicken TMSB4X Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TMSB4X Related Articles
  • TMSB4X Related Research Area

TMSB4X involved in several pathways and played different roles in them. We selected most pathways TMSB4X participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMSB4X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of actin cytoskeletonPIP4K2AA;MYL12.2;ACTB2;FGF7;HRASB;WASLB;PIK3R1;ROCK2A;ITGB2L

TMSB4X has several biochemical functions, for example, actin monomer binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMSB4X itself. We selected most functions TMSB4X had, and list some proteins which have the same functions with TMSB4X. You can find most of the proteins on our site.

Function Related Protein
actin monomer bindingTWF2;LIMA1;MTSS1;ABL2;TMSB;MYL2;MYL3;PKNOX2;TMSB4Y
poly(A) RNA bindingDDX23;FXR2;RPS20;MTPAP;TRIM28;HSPE1;CNOT1;WBP11;DIAPH1
protein bindingTLX2;CD40;PFDN4;SKAP2;ACTR8;STAT4;WDR25;C9orf116;PRH1

TMSB4X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMSB4X here. Most of them are supplied by our site. Hope this information will be useful for your research of TMSB4X.

MLH1; SCHIP1; TK1; TP53; ANXA7

Yang, XR; Koltes, JE; et al. Gene Co-Expression Network Analysis Provides Novel Insights into Myostatin Regulation at Three Different Mouse Developmental Timepoints. PLOS ONE 10:-(2015).
Lan, X; Li, DM; et al. Identification of differentially expressed genes related to metabolic syndrome induced with high-fat diet in E3 rats. EXPERIMENTAL BIOLOGY AND MEDICINE 240:235-241(2015).
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