|Official Full Name||triggering receptor expressed on myeloid cells-like 1|
|Background||TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1;(MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium;signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 (PubMed 12645956); Barrow et al.,;2004 (PubMed 15128762)).|
|Synonyms||TREML1; triggering receptor expressed on myeloid cells-like 1; trem-like transcript 1 protein; dJ238O23.3; TLT1; TREM like transcript 1; triggering receptor expressed on myeloid cells-like protein 1; TLT-1; PRO3438; GLTL1825; MGC119173|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
TREML1 involved in several pathways and played different roles in them. We selected most pathways TREML1 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with TREML1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||RNF220; RAP1GAP2; DYNC1I2; CTSC; RNF182; RAET1E; CTSD; EVL; RNF111; CD300LD|
|Immune System||Mill2; GBP6; LGALS3; LILRB2; TNFRSF13C; TRIM41; TRIM69; KLRB1F; NCKAP1; GRAP2B|
|Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell||CD200R4; SIGLEC5; TREML2; AF251705; OSCAR; TREML4; CD200; Siglece; CD200R1; SIGLEC8|
TREML1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TREML1 itself. We selected most functions TREML1 had, and list some proteins which have the same functions with TREML1. You can find most of the proteins on our site.
|protein binding||MT1A; SLX4; TRIM2; DAZL; KRT18; SDPR; MPHOSPH8; PRKAB1; ZNF41; EAF1|
TREML1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TREML1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TREML1.