treml1
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  • Official Full Name
  • triggering receptor expressed on myeloid cells-like 1
  • Background
  • TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1;(MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium;signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 (PubMed 12645956); Barrow et al.,;2004 (PubMed 15128762)).
  • Synonyms
  • TREML1; triggering receptor expressed on myeloid cells-like 1; trem-like transcript 1 protein; dJ238O23.3; TLT1; TREM like transcript 1; triggering receptor expressed on myeloid cells-like protein 1; TLT-1; PRO3438; GLTL1825; MGC119173
Cat.#:TREML1-2512HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human TREML1 Protein, MYC/DDK-tagged
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Cat.#:TREML1-3401HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TREML1, GST-tagged
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Cat.#:TREML1-373HTag:Fc
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human TREML1 Protein, Fc-tagged
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Cat.#:TREML1-3943HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human TREML1, His tagged
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Cat.#:TREML1-17322MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TREML1 Protein
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Cat.#:Treml1-398MTag:His
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Treml1, His-tagged
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Cat.#:TREML1-4949RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TREML1 Protein, His-tagged
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Cat.#:TREML1-2084HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human TREML1 cell lysate
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Involved Pathway

TREML1 involved in several pathways and played different roles in them. We selected most pathways TREML1 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with TREML1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
UBE2F; MKRN1; NPEPPS; CTSO; ACTR1A; DYNC1H1; PJA2; ASB18; RNF138; KIF20A
Immune System
IFIT3; CTSE; WWP1; SIGLEC10; TRIM68; SIGLEC12; KLRF1; DUSP3; MGC174857; DEFB103A
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
TREML1; CD160; KLRG1; CD300LB; Siglece; CD200R2; LILRA1; TREM1; LILRB4; CD300C

Protein Function

TREML1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TREML1 itself. We selected most functions TREML1 had, and list some proteins which have the same functions with TREML1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ERBB3; TLR6; UBE2R2; FOSL2; EOMESA; MKNK1; CALCOCO1; SIPA1L2; SURF1; USP47

TREML1 Related Articles

Esponda, OL; Hunter, R; et al. Levels of Soluble TREM-Like Transcript 1 in Patients Presenting to the Emergency Department With Chest Pain. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 21:30-34(2015).
Yoon, SH; Lee, YD; et al. TLT-1s, Alternative Transcripts of Triggering Receptor Expressed on Myeloid Cell-like Transcript-1 (TLT-1), Inhibits the Triggering Receptor Expressed on Myeloid Cell-2 (TREM-2)-mediated Signaling Pathway during Osteoclastogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 287:29620-29626(2012).