TREML1 Protein, triggering receptor expressed on myeloid cells-like 1


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Official Full Name triggering receptor expressed on myeloid cells-like 1
Background TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1;(MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium;signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 (PubMed 12645956); Barrow et al.,;2004 (PubMed 15128762)).
Synonyms TREML1; triggering receptor expressed on myeloid cells-like 1; trem-like transcript 1 protein; dJ238O23.3; TLT1; TREM like transcript 1; triggering receptor expressed on myeloid cells-like protein 1; TLT-1; PRO3438; GLTL1825; MGC119173
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Tag :
    • Fc
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TREML1-2084HCL Recombinant Human TREML1 cell lysate Human Cell N/A
    Human TREML1-2512H Recombinant Human TREML1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human TREML1-3401H Recombinant Human TREML1, GST-tagged E.coli GST
    Human TREML1-373H Recombinant Human TREML1 Protein, Fc-tagged HEK293 Fc
    Human TREML1-3943H Recombinant Human TREML1, His tagged Human Cell His
    Mouse TREML1-17322M Recombinant Mouse TREML1 Protein Mammalian Cell His
    Mouse Treml1-398M Recombinant Mouse Treml1, His-tagged NS0 His
    Rhesus Macaque TREML1-4949R Recombinant Rhesus monkey TREML1 Protein, His-tagged Mammalian Cell His

    TREML1 involved in several pathways and played different roles in them. We selected most pathways TREML1 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with TREML1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System RNF220; RAP1GAP2; DYNC1I2; CTSC; RNF182; RAET1E; CTSD; EVL; RNF111; CD300LD
    Immune System Mill2; GBP6; LGALS3; LILRB2; TNFRSF13C; TRIM41; TRIM69; KLRB1F; NCKAP1; GRAP2B
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell CD200R4; SIGLEC5; TREML2; AF251705; OSCAR; TREML4; CD200; Siglece; CD200R1; SIGLEC8

    TREML1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TREML1 itself. We selected most functions TREML1 had, and list some proteins which have the same functions with TREML1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding MT1A; SLX4; TRIM2; DAZL; KRT18; SDPR; MPHOSPH8; PRKAB1; ZNF41; EAF1

    TREML1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TREML1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TREML1.

    Esponda, OL; Hunter, R; et al. Levels of Soluble TREM-Like Transcript 1 in Patients Presenting to the Emergency Department With Chest Pain. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 21:30-34(2015).
    Yoon, SH; Lee, YD; et al. TLT-1s, Alternative Transcripts of Triggering Receptor Expressed on Myeloid Cell-like Transcript-1 (TLT-1), Inhibits the Triggering Receptor Expressed on Myeloid Cell-2 (TREM-2)-mediated Signaling Pathway during Osteoclastogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 287:29620-29626(2012).

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