trim24
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  • Official Full Name
  • tripartite motif containing 24
  • Background
  • TIF1beta is a member of the TIF1 (transcriptional intermediary factor 1) family, a group of transcriptional regulators that play key roles in development and differentiation. Members of this family are characterized by the presence of two conserved motifs
  • Synonyms
  • TRIM24; tripartite motif containing 24; TIF1, transcriptional intermediary factor 1 , tripartite motif containing 24; transcription intermediary factor 1-alpha; hTIF1; RNF82; TIF1A; TIF1-alpha; RING finger protein 82; tripartite motif-containing
Cat.#:TRIM24-166HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIM24, GST-tagged
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Cat.#:TRIM24-223HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIM24 Protein, GST-tagged
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Cat.#:TRIM24-224HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIM24 Protein, His-tagged
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Cat.#:TRIM24-314HTag:His/FLAG
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIM24 protein, His/FLAG-tagged
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Cat.#:TRIM24-315HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human TRIM24 protein, GST-tagged
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Cat.#:TRIM24-316HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human TRIM24 protein, GST-tagged
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Cat.#:TRIM24-3409HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIM24, His-tagged
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Cat.#:TRIM24-17349MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TRIM24 Protein
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Cat.#:TRIM24-4957RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TRIM24 Protein, His-tagged
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Cat.#:TRIM24-858ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TRIM24
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Cat.#:TRIM24-789HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TRIM24 293 Cell Lysate
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Cat.#:Kit-1889Tag:
Source (Host):Species:
Product nameTRIM24 Inhibitor Screening Assay Kit
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Involved Pathway

TRIM24 involved in several pathways and played different roles in them. We selected most pathways TRIM24 participated on our site, such as Disease, Diseases of signal transduction, FGFR1 mutant receptor activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Disease
CDC37; PRELP; CTBP1; ANTXR2; FDXR; OPN1MW; STRA6; IPO5; RNF43; LTF
Diseases of signal transduction
JAG2; OPN1SW; RBP4; TRAT1; FGFR1OP2; LRRFIP1; FGFR1OP; JAG1; TRIM24; OPN1LW
FGFR1 mutant receptor activation
FGFR1OP; CPSF6; FGFR1OP2; TRIM24; LRRFIP1; CUX1; MYO18A
Regulation of Androgen receptor activity
NR2C1; APPBP2; GATA2; SMARCE1; SRY; HOXB13; SPDEF; SENP1; KAT7; NR2C2
Signaling by FGFR in disease
LRRFIP1; FGFR1OP2; TRIM24; CUX1; CPSF6; MYO18A
Signaling by FGFR1 fusion mutants
TRIM24; MYO18A; FGFR1OP2; CUX1; CPSF6
Signaling by FGFR1 in disease
CPSF6; FGFR1OP2; TRIM24; MYO18A; CUX1

Protein Function

TRIM24 has several biochemical functions, for example, chromatin binding, estrogen response element binding, ligand-dependent nuclear receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM24 itself. We selected most functions TRIM24 had, and list some proteins which have the same functions with TRIM24. You can find most of the proteins on our site.
Function
Related Protein
Function chromatin binding
Related Protein C10orf119; GATA6; COQ7; TMPOA; TOX4; NCOA2; FLI1; MED1; TAL1; CCNT1
Function estrogen response element binding
Related Protein TRIM24; TOX3; ESR1; ESR2
Function ligand-dependent nuclear receptor binding
Related Protein SMARCD3; ARID1A; PPARGC1A; UBA3; TADA3; ISL1; NCOA2; SMARCE1; NCOA1; JUND
Function ligase activity
Related Protein RC3H2; SIAH1A; AMFR; RNF4; PELI1; RBCK1; PDZRN3; BIRC2; RNF133; ARIH1
Function lysine-acetylated histone binding
Related Protein PSME4B; SMARCA4; BAZ2A; TAF1L; ATAD2B; PHIP; BRD4; BRD7; TAF1; BAZ1B
Function NOT methylated histone binding
Related Protein TRIM24; CDYL
Function p53 binding
Related Protein EHMT1; ZNF385B; ZMAT3; RFWD3; HTT; TRIAP1; TP53; CDKN2AIP; CDK5; BANP
Function protein binding
Related Protein LSM3; TYRO3; HFE2; ZNF205; Itga10&Itgb1; GNMT; FAM81B; MYL2; ATP2B1; C22orf29
Function protein kinase activity
Related Protein ERBB4A; RPS6KA5; VRK1; SMOK2B; GSK3AA; PRKAG1; MAPKAPK2; CAMK2B1; WEE2; PKMYT1
Function receptor binding
Related Protein MBL2; FIS1; Fgf15; CD70; LAMA4; TNFSF9; MSN; AGXT; SRI; HNF4A
Function sequence-specific DNA binding
Related Protein ENG2A; RBPJ; MAFBA; MYBBP1A; FOXJ2; HOXC9A; GATA1A; OTX1B; CTCFL; RXRAA
Function transcription coactivator activity
Related Protein GTF2A1; STIL; CITED4; DDX17; NR1I3; SOX17; ARL2BP; WWTR1; DDX5; SMARCB1
Function ubiquitin protein ligase activity
Related Protein CDK8; PRPF19; PELI1; WWP1; RNF165; MED23; UBR5; HECW2; RBX1; HERC2
Function ubiquitin-protein transferase activity
Related Protein UBE2D3; WDSUB1; MARCH2; UBE2W; TRIM32; UBE2S; RNF6; PRKCQ; ZYG11; BIRC5B
Function zinc ion binding
Related Protein APOBEC2B; NRD1B; RBM14B; SHRPRBCK1R; AGBL4; VDRA; RNF138; NANOS2; TRIM35-31; TRIM27

Interacting Protein

TRIM24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM24 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM24.
HSPB1; BRCA1; UBE2U; RNF141; TRIM8; RNF181; pi3p; ESR1; ESR2; TRIM33