Human TRIM24 Knockdown Cell Lysate

• Cat.No.: TRIM24-456HKCL
• Product Overview: WB-validated TRIM24 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 117 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg TRIM24 KD HeLa cell lysate
• Protein Families: Druggable Genome, Protein Kinase, Transcription Factors
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: TRIM24 tripartite motif containing 24 [ Homo sapiens (human) ]
• Official Symbol: TRIM24
• Synonyms: TRIM24; tripartite motif containing 24; TIF1, transcriptional intermediary factor 1, tripartite motif containing 24; transcription intermediary factor 1-alpha; hTIF1; RNF82; TIF1A; Tif1a; TIF1-alpha; RING finger protein 82; tripartite motif-containing 24; E3 ubiquitin-protein ligase TRIM24; transcriptional intermediary factor 1; PTC6; TF1A; TIF1; TIF1ALPHA
• Gene ID: 8805
• mRNA Refseq: NM_003852
• Protein Refseq: NP_003843
• MIM: 603406
• UniProt ID: O15164