tyro3
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  • Official Full Name
  • TYRO3 protein tyrosine kinase
  • Background
  • The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]
  • Synonyms
  • TYRO3; TYRO3 protein tyrosine kinase; BYK; Dtk; RSE; Sky; Tif; tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase DTK; tyrosine-protein kinase RSE; tyrosine-protein kinase SKY; tyrosine-protein kinase TIF; tyrosine-protein kinase byk;
Cat.#:Tyro3-414MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse TYRO3 Protein Tyrosine Kinase 3, His-tagged
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Cat.#:TYRO3-254HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human TYRO3 Protein Tyrosine Kinase, GST-tagged, Active
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Cat.#:TYRO3-195HTag:DDK|His
Source (Host):HEK293Species:Human
Product nameRecombinant Human TYRO3 protein, DDK/His-tagged
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Cat.#:TYRO3-196HTag:human|IgG1|Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human TYRO3 protein, Fc-tagged
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Cat.#:TYRO3-31545THTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TYRO3
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Cat.#:TYRO3-3510HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TYRO3, GST-tagged
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Cat.#:TYRO3-3892HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human TYRO3 protein, MYC/DDK-tagged
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Cat.#:TYRO3-484HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human TYRO3 Protein Tyrosine Kinase
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Cat.#:TYRO3-612HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human TYRO3 Protein, DDK-tagged
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Cat.#:TYRO3-749HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human TYRO3 Protein Tyrosine Kinase, GST-His
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Cat.#:TYRO3-17674MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TYRO3 Protein
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Cat.#:TYRO3-6382RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TYRO3 Protein
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Cat.#:TYRO3-6195CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TYRO3
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Cat.#:TYRO3-9000ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TYRO3
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Cat.#:TYRO3-1506HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human TYRO3 (Active), GST-tagged
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Cat.#:TYRO3-615HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TYRO3 293 Cell Lysate
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Protein Function

TYRO3 has several biochemical functions, for example, ATP binding, phosphatidylinositol 3-kinase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TYRO3 itself. We selected most functions TYRO3 had, and list some proteins which have the same functions with TYRO3. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein KIF20B; ORC4L; ENTPD8; UBE2D2; SMARCAL1; C10orf2; KIF2B; MARK2; PRKG1A; TGFBR1A
Function phosphatidylinositol 3-kinase binding
Related Protein IGF1R; LCK; CALM2; INSRR; ATP1A1; PDGFRB; IRS2; FLT3; CORO1A; CALM3
Function protein binding
Related Protein DDIT4L; CD48; COL10A1; SNCA; RBCK1; WDR25; RAB39B; EEF1A2; RWDD3; RRAGD
Function protein heterodimerization activity
Related Protein HIST1H3F; KCNIP1; TBX15; TLR2; TPD52; TRP53; EFHA1; NFYC; DVL3; TCF3
Function protein tyrosine kinase activity
Related Protein PTK7A; KDRL; TEK; MAP2K6; PDGFRB; BAZ1B; MAP2K3; TYK2; KITB; TNK2
Function receptor signaling protein tyrosine kinase activity
Related Protein ERBB3B; EGFR; EGFRA; INSR; ERBB4A; TYRO3; LYN; SYK; KITA; KIT
Function transmembrane receptor protein tyrosine kinase activity
Related Protein FGFR1B; RYK; FLT4; ROR2; PDGFRA; EPHB4B; KDRL; DDR1; EPHB4A; EPHA2
Function virus receptor activity
Related Protein SCARB1; SLC10A1; ACE2; CD4; NPC1; TFRC; SELPLG; CD209; SCARB2; ANPEP

Interacting Protein

TYRO3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TYRO3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TYRO3.
KRTAP5-9; KRTAP10-7; KRTAP10-8; KRTAP10-9; KRT40; MDFI

TYRO3 Related Articles

Nguyen, KQN; Tsou, WI; et al. Overexpression of MERTK Receptor Tyrosine Kinase in Epithelial Cancer Cells Drives Efferocytosis in a Gain-of-Function Capacity. JOURNAL OF BIOLOGICAL CHEMISTRY 289:25737-25749(2014).
Shibata, T; Habiel, DM; et al. Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma. JOURNAL OF IMMUNOLOGY 192:3569-3581(2014).