Recombinant Human TYRO3 Protein Tyrosine Kinase

• Cat.No.: TYRO3-484H

Specification

• Cat. No.: TYRO3-484H
• Description: Dtk belongs to a recently recognized subfamily of receptor tyrosine kinases that also includes Ufo (Axl/Ark) and Mer (Eyk). Ligands for Dtk and Ufo have been identified as protein S and the related molecule Gas6, respectively. Dtk is likely to be involved in the regulation of hematopoiesis, particularly during the embryonic stages of blood cell development. DTK is also abundantly expressed in adult kidney, testis, and ovary.
• Source: Mammalian cells
• Molecular Weight: The predicted molecular weight of Recombinant Human Dtk is Mr 69 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100-110 kDa.
• State Of Matter: Lyophilized.
• Purity: > 90% by SDS Page and analyzed by silver stain.
• Endotoxin: < 1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: TYRO3 TYRO3 protein tyrosine kinase [ Homo sapiens ]
• Synonyms: TYRO3; TYRO3 protein tyrosine kinase; BYK; Brt; Dtk; RSE; Sky; Tif; FLJ16467; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase RSE; Tyrosine-protein kinase SKY; Tyrosine-protein kinase DTK; Tyrosine-protein kinase byk; EC 2.7.10.1
• Gene ID: 7301
• mRNA Refseq: NM_006293
• Protein Refseq: NP_006284
• UniProt ID: Q06418
• Chromosome Location: 15q15.1-q21.1
• MIM: 600341
• Function: ATP binding; nucleotide binding; phosphoinositide 3-kinase binding; protein binding; receptor activity; receptor signaling protein tyrosine kinase activity; transferase activity; transmembrane receptor protein tyrosine kinase activity