ucp2
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  • Official Full Name
  • uncoupling protein 2 (mitochondrial, proton carrier)
  • Background
  • UCP2 also known as mitochondrial uncoupling protein 2 is a 33 kD member of the mitochondrial anion carrier protein family. This protein is expressed in the mitochondria and is highly expressed in brain, kidney, liver, brown adipose tissue, heart, and musc
  • Synonyms
  • UCP2; uncoupling protein 2 (mitochondrial, proton carrier); mitochondrial uncoupling protein 2; SLC25A8; UCP 2; solute carrier family 25 member 8; UCPH; BMIQ4
Cat.#:UCP2-619HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UCP2 Protein, His-tagged
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Cat.#:UCP2-17790MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UCP2 Protein
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Cat.#:Ucp2-7917MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ucp2 protein, His-tagged
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Cat.#:UCP2-6422RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UCP2 Protein
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Cat.#:Ucp2-7918RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ucp2 protein, His-tagged
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Cat.#:UCP2-5091RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey UCP2 Protein, His-tagged
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Cat.#:UCP2-8784ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UCP2
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Cat.#:UCP2-525HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human UCP2 293 Cell Lysate
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Involved Pathway

UCP2 involved in several pathways and played different roles in them. We selected most pathways UCP2 participated on our site, such as Electron Transport Chain, Energy Metabolism, FOXA2 and FOXA3 transcription factor networks, which may be useful for your reference. Also, other proteins which involved in the same pathway with UCP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Electron Transport Chain
ATP5H; COX7C; COX6C; COX6A2; ATPIF1; UCP3; COX6B1; SCO1; COX15; COX4I1
Energy Metabolism
ESRRA; PPARGC1B; UCP2; MYBBP1A; TFB1M; TFB2M; GABPA; UCP3; MEF2B
FOXA2 and FOXA3 transcription factor networks
CPT1A; UCP2; DLK1; CEBPA; CPT1C; KCNJ11; TTR; FOXA1; FOXF1; CPT1B
Metabolism
APOBB.1; CKB; CYB5R3; KCNC2; SULT1C2; SLC16A8; GSTO2; PPM1L; ITPA; ABHD10
Mitochondrial Uncoupling Proteins
UCP2; UCP3; SLC25A27; SLC25A14
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
LRPPRC; SLC25A14; C2orf56; COX18; SURF1; ATP5S; COX14; ATP5L; TACO1; SCO1
The citric acid (TCA) cycle and respiratory electron transport
PDK3; PDPR; NDUFAF3; UCP3; NDUFAF6; C20orf7; C2orf56; ADHFE1; COX18; NDUFAF4
The fatty acid cycling model
UCP2; UCP3; SLC25A14; SLC25A27

Protein Function

UCP2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UCP2 itself. We selected most functions UCP2 had, and list some proteins which have the same functions with UCP2. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein FRS2; NFKBIE; MAGEA4; CLEC1B; YWHAE; ZC3H14; HNRNPUL1; THOP1; RORC; MBP

Interacting Protein

UCP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UCP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UCP2.
KRTAP10-7; pepP

UCP2 Related Articles

Zhu, R; Rupprecht, A; et al. Mapping the Nucleotide Binding Site of Uncoupling Protein 1 Using Atomic Force Microscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 135:3640-3646(2013).
Kwok, KHH; Ho, PWL; et al. Mitochondrial UCP5 is neuroprotective by preserving mitochondrial membrane potential, ATP levels, and reducing oxidative stress in MPP+ and dopamine toxicity. FREE RADICAL BIOLOGY AND MEDICINE 49:1023-1035(2010).