VASP

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VASP

Official Full Name VASP vasodilator-stimulated phosphoprotein
Background VASP (vasodilator stimulated phosphoprotein) plays an important role in ANF/NO/cGMP Protein kinase and cAMP/cAMP Protein kinase signalling pathways. VASP is expressed in almost all human and animal cell lines; particularly high concentrations are found in thrombocytes, vascular smooth muscle cells and fibroblasts. In cultured cells VASP is associated with focal contacts, cell-cell-contacts, microfilaments and dynamic membrane regions such as the leading edge. In vitro binding data show that VASP binds to profilin, zyxin, vinculin, and the Listeria spp. surface protein ActA. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation.
Synonyms VASP; vasodilator-stimulated phosphoprotein;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human VASP-1570H Recombinant Human VASP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Vasp-6901M Recombinant Mouse Vasp Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human VASP-30994TH Recombinant Human VASP, His-tagged E.coli His
    Human VASP-3500H Recombinant Human VASP, His-tagged E.coli His
    Human VASP-426HCL Recombinant Human VASP 293 Cell Lysate HEK293 N/A
    Mouse VASP-17986M Recombinant Mouse VASP Protein Mammalian Cell His

    VASP involved in several pathways and played different roles in them. We selected most pathways VASP participated on our site, such as Rap signaling pathway, cGMP-PKG signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with VASP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Rap signaling pathway VEGFB; PRKD1; PLCB2; LPAR2; FGFR4; INS2; CDH1; LPAR3; Pdgfa&Pdgfb; RAPGEF1
    cGMP-PKG signaling pathway RAF1; SLC25A31; GTF2I; PPP3CB; SLC25A4; VDAC3; PPP3R2; GNAQ; ITPR1; ATP1A3
    Focal adhesion FYN; RHOAA; ZYX; COL6A6; AKT1; RAC1B; CDC42L2; COL6A2; ACTN2; PRKCG
    Platelet activation F2RL3; MAPK3; ITGA2; ACTB; GNAI3; NOS3; PIK3R1; MAPK11; RAP1A; ITGB3
    Fc gamma R-mediated phagocytosis PRKCG; HCK; MAPK3; CDC42; FCGR1A; VAV3; ARF6; LIMK1; PLD1; CFL1
    Leukocyte transendothelial migration RAC1; ACTB; CLDN5; PIK3CA; PIK3CG; TXK; PRKCG; CLDN3; BCAR1; ACTN2

    VASP has several biochemical functions, for example, SH3 domain binding, actin binding, profilin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VASP itself. We selected most functions VASP had, and list some proteins which have the same functions with VASP. You can find most of the proteins on our site.

    Function Related Protein
    SH3 domain binding RAD9; FUT8; PLSCR1; QKI; GJA1; DOCK4; SH3BP1; ARHGAP6; MVB12A; PDCD6IP
    actin binding MTAP1A; SPTBN1; MYH1; MYH8; MKL1B; CORO7; FER; ENC1; MYLK; CAPZA1A
    profilin binding CYFIP1; WIPF1; HTT; RHOQ; FMNL1; VASP; DIAP1; PCLO; DIAPH1; CTTN
    protein binding CRB3; TEC; TLR13; SULT1C2; WRNIP1; CCDC137; KIAA1274; DPM1; RPS19; ACTN2

    VASP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VASP here. Most of them are supplied by our site. Hope this information will be useful for your research of VASP.

    XIRP1; BAIAP2; FGFR1OP; SCGB2A2; ABI2

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