WNT3A
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Official Full Name
wingless-type MMTV integration site family, member 3A
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Overview
The Wnt family includes several secreted glycoproteins that play important roles in animal development. There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins. Wnt members bind to the Frizzled family of seven-pass transm -
Synonyms
WNT3A; wingless-type MMTV integration site family, member 3A; protein Wnt-3a; MGC119418; MGC119419; MGC119420;
- Recombinant Proteins
- Cell & Tissue Lysates
- GMP Proteins
- Protein Pre-coupled Magnetic Beads
- Cattle
- Chicken
- Human
- Mouse
- Murine
- Rat
- Zebrafish
- CHO
- E. coli
- E.coli
- HEK293
- Human Cell
- Human cells
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Mouse cells
- Wheat Germ
- Yeast
- C
- His
- GST
- His (Fc)
- Avi
- His|S
- His|T7
- N/A
- N
- Strep II
- Involved Pathway
- Protein Function
- Interacting Protein
- WNT3A Related Articles
- WNT3A Related Gene Family
- WNT3A Related Research Area
WNT3A involved in several pathways and played different roles in them. We selected most pathways WNT3A participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Wnt signaling pathway | TLE3A;FZD5;INVS;NKD1;PRICKLE1;GSK3AA;PPP3CCA;PSEN1;PPARDB |
Hedgehog signaling pathway | WNT8A;DHH;WNT7B;GAS1B;PRKACG;PRKACAA;SAP18;CSNK1G2B;WNT6 |
Hippo signaling pathway | APC2;AXIN1;BMPR1B;WTIP;SERPINE1;MOB1A;WNT11;WWTR1;CTNNA3 |
Signaling pathways regulating pluripotency of stem cells | PIK3R1;ACVR2B;WNT3A;ID4;WNT2B;OTX1;GRB2;PIK3CA;RAF1 |
Melanogenesis | WNT8B;PRKACAA;WNT2B;HRASB;GNAO1A;ADCY2B;PRKACB;TYRP1B;GNAI3 |
HTLV-I infection | CCND2;HLA-DOA;HLA-DRB5;BCL2L1;TBPL2;PTTG2;PPP3R1;POLB;MYB |
Pathways in cancer | HSP90AA1;LPAR5;ITGA2;FLT3LG;PLEKHG5;BID;GNAI3;RAF1;WNT7A |
Proteoglycans in cancer | HPSE;VEGFA;MAPK3;PLCE1;FZD9;ITPR1;WNT8B;FLNC;SOS1 |
MicroRNAs in cancer | PRKCE;EFNA3;CYP24A1;GLS2;MDM2;BMI1;EZH2;PDGFB;FOXP1 |
Basal cell carcinoma | SUFU;FZD3;WNT1;AXIN1;WNT2;FZD2;APC2;Fzd4;FZD5 |
WNT3A has several biochemical functions, for example, frizzled binding, frizzled-2 binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT3A itself. We selected most functions WNT3A had, and list some proteins which have the same functions with WNT3A. You can find most of the proteins on our site.
Function | Related Protein |
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frizzled binding | ZNRF3;CTHRC1;WNT10B;WNT3;FZD1;DVL3;LRP6;SFRP1;WNT5B |
frizzled-2 binding | WNT3A;WNT5A |
protein binding | ATP6V1E1;PNMA5;SOCS2;PROX1;OIT3;UNC119B;GDAP2;MRPL11;PNKP |
protein domain specific binding | SERPINB1A;ETV6;YWHAE;CASP2;PRKAR2B;ARFIP2;STXBP1;CENPJ;YWHAB |
receptor agonist activity | NODAL;WNT2;CXCL13;WNT3A;VEGFA;GAS6;WNT8A;WNT5A;WNT1 |
transcription coactivator activity | MYCBP;CDK7;ATXN7L3;JUNB;GMEB1;NR2F1;NFE2L3;GTF2A1L;SMARCD1 |
WNT3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT3A here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT3A.
FZD8; LRP6; Fzd8
- Q&As
- Reviews
Q&As (6)
Ask a questionNo interaction between CDH16 protein and WNT3A protein has been found.
The WNT3A protein plays an important role in embryonic development. It is involved in the formation of multiple embryonic organs, directed cell migration, and the establishment of tissue polarity.
Yes, multiple factors have been found in the WNT signaling pathway that regulate the expression and function of WNT3A protein, including Axin, APC, etc.
The WNT3A protein is in the starting position in the Wnt signaling pathway, and it is able to bind to the Wnt receptor and initiate the signaling cascade.
WNT3A protein is closely related to cancer stem cells. It may be involved in the self-renewal and differentiation regulation of cancer stem cells, which is of great significance for tumor development and treatment.
Clinical research on WNT3A protein is still ongoing. Studies have shown the important role of WNT3A protein in tumors, neurological diseases, bone metabolism diseases, etc., and future research will further explore its application potential in disease diagnosis, treatment and prognosis assessment.
Customer Reviews (3)
Write a reviewThis protein is highly expressed and can efficiently synthesize a large number of target proteins in host cells.
This protein has therapeutic effects on specific disease models and is a promising candidate for new drugs.
The laboratory personnel feedback that the protein is easy to operate, can meet the experimental needs, and has a good cost performance.
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