alox15b

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alox15b

Official Full Name arachidonate 15-lipoxygenase, type B
Background This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms ALOX15B; arachidonate 15-lipoxygenase, type B; arachidonate 15 lipoxygenase, second type; arachidonate 15-lipoxygenase B; 15 LOX 2; 15-LOX-B; 15S-lipoxygenase; arachidonate 15-lipoxygenase 2; arachidonate omega(6) lipoxygenase; arachidonate 15-lipoxygenas
    • Species :
    • Human
    • Rat
    • Source :
    • E. coli
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • GST
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ALOX15B-054H Recombinant Human ALOX15B Protein, His-tagged E. coli His
    Human ALOX15B-001HCL Recombinant Human ALOX15B cell lysate Insect Cell N/A
    Human ALOX15B-002HCL Recombinant Human ALOX15B cell lysate Insect Cell N/A
    Human ALOX15B-26021TH Recombinant Human ALOX15B Wheat Germ N/A
    Human ALOX15B-408H Recombinant Human ALOX15B, Gly & Pro tagged Insect Cell Fc/His
    Human ALOX15B-40H Recombinant Human ALOX15B Protein, His-tagged E.coli His
    Human ALOX15B-486H Recombinant Human ALOX15B Protein, GST-tagged Wheat Germ GST
    Human ALOX15B-488H Recombinant Human ALOX15B, His-GST tagged Insect Cell Fc
    Human ALOX15B-580H Recombinant Human Arachidonate 15-lipoxygenase, Type B, His-tagged E.coli His
    Human ALOX15B-6849H Recombinant Human ALOX15B protein, His & T7-tagged E.coli His/T7
    Rat ALOX15B-637R Recombinant Rat ALOX15B Protein Mammalian Cell His
    Rat Alox15b-6850R Recombinant Rat Alox15b protein, His & T7-tagged E.coli His/T7

    alox15b involved in several pathways and played different roles in them. We selected most pathways alox15b participated on our site, such as Arachidonic acid metabolism, Metabolic pathways, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with alox15b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism CYP4A10; GGTLC1; ALOX12B; CYP2AD3; CYP2C19; AKR1C6; DPEP1; DPEP2; CYP2P8; CYP4F18
    Metabolic pathways NDUFS3; ISYNA1; G6PC3; ACAA1; HSD3B5; ACAT2; DPM3; ALDH3B1; TDO2; PLCB4
    Serotonergic synapse GNAI1; PRKCG; ALOX5; GNG3; CYP2C39; CYP2J5; HTR3A; GNG5; HTR1A; ALOX12

    alox15b has several biochemical functions, for example, arachidonate 15-lipoxygenase activity, arachidonate 8(S)-lipoxygenase activity, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by alox15b itself. We selected most functions alox15b had, and list some proteins which have the same functions with alox15b. You can find most of the proteins on our site.

    Function Related Protein
    arachidonate 15-lipoxygenase activity ALOX15B; ALOX8; ALOX15
    arachidonate 8(S)-lipoxygenase activity ALOX8; ALOX15B
    calcium ion binding CAPN2; MYL12.1; ACTN1; NRXN1; AOC3; THBS3; CAPSLA; CDH18A; VIL1; ICN
    iron ion binding CYP39A1; HBB-Y; TPH1A; CYGB1; CYP2K16; MFI2; CYP1A1; CYP2X10.2; CYP2N13; EGLN1
    linoleate 13S-lipoxygenase activity ALOX8; ALOX15B; ALOX12
    lipid binding BPIFB2; YBX2; STARD13; SH3GLB1; LIPF; TRIP10A; STARD8; AP2M1; CYTH2; FFAR3

    alox15b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with alox15b here. Most of them are supplied by our site. Hope this information will be useful for your research of alox15b.

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