Recombinant Human ALOX15B Protein, GST-tagged

• Cat.No.: ALOX15B-486H
• Product Overview: Human ALOX15B full-length ORF ( AAH35217.1, 1 a.a. - 676 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 102.3 kDa
• AA Sequence: MAEFRVRVSTGEAFGAGTWDKVSVS IVGTRGESPPLPLDNLGKEFTAGAE EDFQVTLPEDVGRVLLLRVHKAPPV LPLLGPLAPDAWFCRWFQLTPPRGG HLLFPCYQWLEGAGTLVLQEGTAKV SWADHHPVLQQQRQEELQARQEMYQ WKAYNPGWPHCLDEKTVEDLELNIK YSTAKNANFYLQAGSAFAEMKIKGL LDRKGLWRSLNEMKRIFNFRRTPAA EHAFEHWQEDAFFASQFLNGLNPVL IRRCHYLPKNFPVTDAMVASVLGPG TSLQAELEKGSLFLVDHGILSGIQT NVINGKPQFSAAPMTLLYQSPGCGP LLPLAIQLSQTPGPNSPIFLPTDDK WDWLLAKTWVRNAEFSFHEALTHLL HSHLLPEVFTLATLRQLPHCHPLFK LLIPHTRYTLHINTLARELLIVPGQ VVDRSTGIGIEGFSELIQRNMKQLN YSLLCLPEDIRTRGVEDIPGYYYRD DGMQIWGAVERFVSEIIGIYYPSDE SVQDDRELQAWVREIFSKGFLNQES SGIPSSLETREALVQYVTMVIFTCS AKHAAVSAGQFDSCAWMPNLPPSMQ LPPPTSKGLATCEGFIATLPPVNAT CDVILALWLLSKEPGDQRPLGTYPD EHFTEEAPRRSIATFQSRLAQISRG IQERNRGLVLPYTYLDPPLIENSVS I
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALOX15B arachidonate 15-lipoxygenase, type B [ Homo sapiens ]
• Official Symbol: ALOX15B
• Synonyms: ALOX15B; arachidonate 15-lipoxygenase, type B; arachidonate 15 lipoxygenase, second type; arachidonate 15-lipoxygenase B; 15 LOX 2; 15-LOX-B; 15S-lipoxygenase; arachidonate 15-lipoxygenase 2; arachidonate omega(6) lipoxygenase; arachidonate 15-lipoxygenase type II; arachidonate 15-lipoxygenase, second type; 15-LOX-2
• Gene ID: 247
• mRNA Refseq: NM_001039130
• Protein Refseq: NP_001034219
• MIM: 603697
• UniProt ID: O15296