arhgef2

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arhgef2

Official Full Name Rho/Rac guanine nucleotide exchange factor (GEF) 2
Background Rho family small GTPases regulate processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of GDP for GTP. GEF-H1 is a Rho GEF that localiz
Synonyms ARHGEF2; Rho/Rac guanine nucleotide exchange factor (GEF) 2; rho guanine nucleotide exchange factor 2; GEF H1; KIAA0651; LFP40; P40; microtubule-regulated Rho-GEF; guanine nucleotide exchange factor H1
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARHGEF2-1682H Recombinant Human ARHGEF2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ARHGEF2-785H Recombinant Human ARHGEF2 protein, GST-tagged Wheat Germ GST
    Human ARHGEF2-8732HCL Recombinant Human ARHGEF2 293 Cell Lysate HEK293 N/A
    Mouse Arhgef2-1297M Recombinant Mouse Arhgef2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat ARHGEF2-770R Recombinant Rat ARHGEF2 Protein Mammalian Cell His

    arhgef2 involved in several pathways and played different roles in them. We selected most pathways arhgef2 participated on our site, such as Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with arhgef2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Pathogenic Escherichia coli infection NCK2; FYN; TUBB2B; TUBA3C; WAS; PRKCA; OCLN; KRT18; TUBA3E; TUBB6

    arhgef2 has several biochemical functions, for example, Rac GTPase binding, Rac guanyl-nucleotide exchange factor activity, Rho GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by arhgef2 itself. We selected most functions arhgef2 had, and list some proteins which have the same functions with arhgef2. You can find most of the proteins on our site.

    Function Related Protein
    Rac GTPase binding CAV1; ARHGEF2; SRGAP2; PKN1; DOCK4; NOX1; RALBP1; FMNL1; SRGAP2B; EPS8
    Rac guanyl-nucleotide exchange factor activity ARHGEF2; VAV1; ALS2; VAV3; FARP1; PREX2; ARHGEF4; FARP2; DOCK2; SPATA13
    Rho GTPase binding ECT2; DOCK10; CDC42BPB; KIF3B; INF2; ROCK2B; IQGAP3; ROCK2A; RHOH; PARD6A
    Rho guanyl-nucleotide exchange factor activity ALS2CL; FGD1; FARP2; DOCK11; TRIO; ARHGEF7; FGD4A; VAV3B; C3A.1; VAV3
    microtubule binding NEFM; TERF1; MAPRE2; NME8; NEFH; KRIT1; PSRC1; MTAP4; EML2; ZNF207
    protein binding ULK3; MSR1; RPL13; C19orf47; SMPDL3A; USP10; NAA38; MKI67; STOML2; FLCN
    transcription factor binding SUFU; RBFOX2; RELA; SRY; PIK3R1; HDAC7; NFIA; CREBBP; FOSB; PPARGC1A
    zinc ion binding ADAMTS18; LHX2A; BMI1A; RNF135; EHMT1; TRIM63; RNF181; RNF31; TRIM2; S100A3

    arhgef2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with arhgef2 here. Most of them are supplied by our site. Hope this information will be useful for your research of arhgef2.

    YWHAG; MYC; YWHAZ; RPP25L; ANKRD28; NFKBIE; PAK4; MARK2; KSR1; q81ql4_bacan; pi3p; 15-deoxy-delta(12,14; ssrna_ug

    Zheng, ZL; Liebers, M; et al. Anchored multiplex FOR for targeted next-generation sequencing. NATURE MEDICINE 20:1479-1484(2014).
    Huang, IH; Hsiao, CT; et al. GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment. JOURNAL OF CELL SCIENCE 127:4186-4200(2014).

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