|Official Full Name||Rho/Rac guanine nucleotide exchange factor (GEF) 2|
|Background||Rho family small GTPases regulate processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of GDP for GTP. GEF-H1 is a Rho GEF that localiz|
|Synonyms||ARHGEF2; Rho/Rac guanine nucleotide exchange factor (GEF) 2; rho guanine nucleotide exchange factor 2; GEF H1; KIAA0651; LFP40; P40; microtubule-regulated Rho-GEF; guanine nucleotide exchange factor H1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
arhgef2 involved in several pathways and played different roles in them. We selected most pathways arhgef2 participated on our site, such as Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with arhgef2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Pathogenic Escherichia coli infection||NCK2; FYN; TUBB2B; TUBA3C; WAS; PRKCA; OCLN; KRT18; TUBA3E; TUBB6|
arhgef2 has several biochemical functions, for example, Rac GTPase binding, Rac guanyl-nucleotide exchange factor activity, Rho GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by arhgef2 itself. We selected most functions arhgef2 had, and list some proteins which have the same functions with arhgef2. You can find most of the proteins on our site.
|Rac GTPase binding||CAV1; ARHGEF2; SRGAP2; PKN1; DOCK4; NOX1; RALBP1; FMNL1; SRGAP2B; EPS8|
|Rac guanyl-nucleotide exchange factor activity||ARHGEF2; VAV1; ALS2; VAV3; FARP1; PREX2; ARHGEF4; FARP2; DOCK2; SPATA13|
|Rho GTPase binding||ECT2; DOCK10; CDC42BPB; KIF3B; INF2; ROCK2B; IQGAP3; ROCK2A; RHOH; PARD6A|
|Rho guanyl-nucleotide exchange factor activity||ALS2CL; FGD1; FARP2; DOCK11; TRIO; ARHGEF7; FGD4A; VAV3B; C3A.1; VAV3|
|microtubule binding||NEFM; TERF1; MAPRE2; NME8; NEFH; KRIT1; PSRC1; MTAP4; EML2; ZNF207|
|protein binding||ULK3; MSR1; RPL13; C19orf47; SMPDL3A; USP10; NAA38; MKI67; STOML2; FLCN|
|transcription factor binding||SUFU; RBFOX2; RELA; SRY; PIK3R1; HDAC7; NFIA; CREBBP; FOSB; PPARGC1A|
|zinc ion binding||ADAMTS18; LHX2A; BMI1A; RNF135; EHMT1; TRIM63; RNF181; RNF31; TRIM2; S100A3|
arhgef2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with arhgef2 here. Most of them are supplied by our site. Hope this information will be useful for your research of arhgef2.
YWHAG; MYC; YWHAZ; RPP25L; ANKRD28; NFKBIE; PAK4; MARK2; KSR1; q81ql4_bacan; pi3p; 15-deoxy-delta(12,14; ssrna_ug