| Official Full Name | AT rich interactive domain 4B (RBP1-like) |
| Background | This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized |
| Synonyms | ARID4B; AT rich interactive domain 4B (RBP1-like); AT rich interactive domain 4B (RBP1 like) , RBP1L1, retinoblastoma binding protein 1 like 1; AT-rich interactive domain-containing protein 4B; BCAA; BRCAA1; SAP180; Rb-binding protein homolog; SIN3A-ass; SOLH; small optic lobes homolog (Drosophila); CAPN15; MGC131491; calpain-15; OTTHUMP00000147599; small optic lobes (Drosophila) homolog |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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ARID4B involved in several pathways and played different roles in them. We selected most pathways ARID4B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARID4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ARID4B has several biochemical functions, for example, DNA binding, protein binding, transcription regulatory region DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARID4B itself. We selected most functions ARID4B had, and list some proteins which have the same functions with ARID4B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | TOP2A; SOX15; ZFP410; GFI1B; ZFP37; PQBP1; TCF25; ZNF80; HNF1B; TEAD1 |
| protein binding | ACSS1; S100A2; CRYGC; EYA1; PRMT6; C19orf25; SIKE1; PTPRO; EIF2AK3; ASAP3 |
| transcription regulatory region DNA binding | SFPQ; TBX16; MZF1; KLF1; CCNT1; H2AFY; IKZF4; KLF11; GATA4; SMAD4 |
ARID4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARID4B here. Most of them are supplied by our site. Hope this information will be useful for your research of ARID4B.
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