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Official Full Name actin related protein 2/3 complex, subunit 2, 34kDa
Background This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
Synonyms ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa; actin related protein 2/3 complex, subunit 2 (34 kD); actin-related protein 2/3 complex subunit 2; ARC34; p34 Arc; arp2/3 complex 34 kDa subunit; ARP2/3 protein complex subunit 34; PRO2446; p34-Arc; PNAS-139
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Human Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARPC2-151H Recombinant Human ARPC2 Protein, His-tagged Human Cells His
    Human ARPC2-702H Recombinant Human ARPC2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ARPC2-7566H Recombinant Human ARPC2, His-tagged E.coli His
    Human ARPC2-846H Recombinant Human ARPC2 protein, GST-tagged Wheat Germ GST
    Human ARPC2-850H Recombinant Human ARPC2, His-tagged E.coli His
    Human ARPC2-8685HCL Recombinant Human ARPC2 293 Cell Lysate HEK293 N/A
    Human ARPC2-9883H Recombinant Human ARPC2, His-tagged E.coli His
    Mouse Arpc2-1725M Recombinant Mouse Arpc2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat Arpc2-3105R Recombinant Rat Arpc2, His-tagged E.Coli or Yeast His
    Rhesus Macaque ARPC2-416R Recombinant Rhesus monkey ARPC2 Protein, His-tagged Mammalian Cell His
    Zebrafish ARPC2-11974Z Recombinant Zebrafish ARPC2 Mammalian Cell His

    arpc2 involved in several pathways and played different roles in them. We selected most pathways arpc2 participated on our site, such as Axon guidance, B Cell Receptor Signaling Pathway, Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with arpc2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance SRGAP1; CNTN6; PTK2; ACTR2; FRS2; COL4A5; FRS3; DPYSL3; LIMK2; ARPC2
    B Cell Receptor Signaling Pathway CRK; HRAS; IKBKG; BTK; DOK1; NFATC3; ITK; HDAC5; RAC1; FOS
    Bacterial invasion of epithelial cells WAS; ARPC2; FN1; ARPC5; ITGA5; CRK; CBL; CD2AP; CAV3; RHOA
    CDC42 signaling events CFL1; TNK2; ARPC2; CTNNA1; ARPC5; ARPC1B; EPS8; BAIAP2; ARPC3; ACTR2
    Developmental Biology CFC1; MED7; ACTR3; EPHB4B; CLTA; FGF8B; DLG3; ARPC4; CSNK2A2; SEMA3AB
    EPH-Ephrin signaling EPHA2; ACTR2; ACTR2B; ARHGEF28; CLTB; EFNB3B; ARPC1A; MYL12B; ARPC1B; EFNA3
    EPHB-mediated forward signaling ARPC1A; ACTR2B; CFL1; ARPC2; ACTR2; EPHB3A; EFNB3; ARPC5; ITSN1; ARPC3
    Endocytosis PSD4; PARD6B; ARF3B; RHOAB; MVB12BA; VPS24; TGFB1A; ARPC5L; SPG20; TFRC

    arpc2 has several biochemical functions, for example, AP-1 adaptor complex binding, Arp2/3 complex binding, contributes_to actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by arpc2 itself. We selected most functions arpc2 had, and list some proteins which have the same functions with arpc2. You can find most of the proteins on our site.

    Function Related Protein
    AP-1 adaptor complex binding ARPC2; AP1AR; RAB32; RAB38
    Arp2/3 complex binding WHAMM; GMFG; SNX9; GMFB; PICK1; ARPC2; HAND2; CORO1B
    contributes_to actin filament binding ARPC4; ARPC3; MYH10; ARPC5; MYH9; ARPC1B; ACTR2; ARPC2; ACTR3
    kinesin binding KLC2; SERPINB1A; PLEKHM2; KTN1; KIAA1279; NEFH; KIF1B; CLSTN1; KIF18B; KIFAP3B
    protein binding BFSP1; PDK1; MXD1; UCKL1; EHMT1; RHOG; KCNQ4; ANKHD1; FAM184A; ACE2
    structural constituent of cytoskeleton TUBG1; EPB41; INA; ARPC4; F-KER; TUBGCP5; KRT16; SPRR2A1; TUBB1; AGRN

    arpc2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with arpc2 here. Most of them are supplied by our site. Hope this information will be useful for your research of arpc2.

    CORO1B; VCL; VCL; HLA-B; Wasf1; ACTR3B; TRAF6; q7ard3_yerpe; tdh; MYH9; IQGAP1; CAPZA2; Tpm1; Actb; ACTR2; PPP1CB

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