Recombinant Human ATG5 Protein, His-tagged
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| Cat.No. : | ATG5-18H |
| Product Overview : | Recombinant human ATG5 protein (2-275) with a N-terminal His-tag was expressed in E. coli. |
| Description : | The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | 50 mM HEPES, pH 8.0, 150 mM sodium chloride, and 10% glycerol |
| Molecular Mass : | 34.5 kDa |
| Protein length : | 2-275 |
| Purity : | ≥70% estimated by SDS-PAGE |
| Applications : | WB |
| Stability : | ≥ 1 year |
| Storage : | Store at -80 centigrade |
| SDS-PAGE of ATG5 : |
Lane 1: MW Markers, Lane 2: ATG5 (human recombinant) (2 µg), Lane 3: ATG5 (human recombinant) (4 µg). Representative gel image shown; actual purity may vary between each batch. |
| Gene Name : | ATG5 autophagy related 5 [ Homo sapiens (human) ] |
| Official Symbol : | ATG5 |
| Synonyms : | ATG5; autophagy related 5; ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE; autophagy protein 5; APG5 autophagy 5-like; ATG5 autophagy related 5 homolog; apoptosis-specific protein |
| Gene ID : | 9474 |
| mRNA Refseq : | NM_001286106 |
| Protein Refseq : | NP_001273035 |
| MIM : | 604261 |
| UniProt ID : | Q9H1Y0 |
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Atg12ATG3P1ATG5Atg7ATG16L1ATG4BATG4DATG3ATG4AATG4CATG10ATG8ATG16L2ATG2BATG9AATG9BATG9ATG13ATG14ATG2A
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