BMP1

  • Official Full Name

    bone morphogenetic protein 1

  • Overview

    This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008]
  • Synonyms

    BMP1; bone morphogenetic protein 1; PCP; TLD; OI13; PCP2; PCOLC; mammalian tolloid protein; procollagen C-proteinase 3; procollagen C-endopeptidase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BMP1-707H Active Recombinant Human BMP1, His-tagged Mammalian cells His
Human BMP1-571H Active Recombinant Human Bone Morphogenetic Protein 1, His-tagged Mammalian cells His
Human BMP1-662H Recombinant Human BMP1 protein, His & GST-tagged E.coli His/GST
Human BMP1-256H Recombinant Human BMP1 Protein, GST-tagged Wheat Germ GST
Human BMP1-10247H Recombinant Human BMP1, His-tagged E.coli His
Human BMP1-26314TH Recombinant Human BMP1 protein, GST-tagged Wheat Germ GST
Human BMP1-8436HCL Recombinant Human BMP1 293 Cell Lysate HEK293 N/A
Human BMP1-2548H Recombinant Human BMP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human BMP1-1734HF Recombinant Full Length Human BMP1 Protein, GST-tagged In Vitro Cell Free System GST
Human BMP1-30198H Recombinant Human BMP1 protein, GST-tagged E.coli GST
Human BMP1-2548H-B Recombinant Human BMP1 Protein Pre-coupled Magnetic Beads HEK293
Human BMP1-2595H Recombinant Human BMP1 protein, His-tagged E.coli His
Mouse BMP1-2428M Recombinant Mouse BMP1 Protein Mammalian Cell His
Mouse Bmp1-663M Recombinant Mouse Bmp1 protein, His-tagged E.coli His
Mouse Bmp1-4004M Recombinant Mouse Bmp1 Protein (Glu615-Ser848), N-GST tagged E.coli N-GST
Mouse BMP1-1050M Recombinant Mouse BMP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BMP1-1050M-B Recombinant Mouse BMP1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque BMP1-546R Recombinant Rhesus monkey BMP1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque BMP1-374R-B Recombinant Rhesus Macaque BMP1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque BMP1-374R Recombinant Rhesus Macaque BMP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BMP1 Related Articles
  • BMP1 Related Gene Family

BMP1 involved in several pathways and played different roles in them. We selected most pathways BMP1 participated on our site, such as Adipogenesis, Anchoring fibril formation, Assembly of collagen fibrils and other multimeric structures, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AdipogenesisEGR2B;DDIT3;AGT;SMAD3B;GTF3AA;CEBPA;KLF7;NRIP1;MIXL1
Anchoring fibril formationBMP1B;TLL1;BMP1A;BMP1;TLL2
Assembly of collagen fibrils and other multimeric structuresLOXL2;COL4A3;TLL1;PCOLCE;COL11A1B;CTSL1;COL5A2;CD151;PLEC
Cardiac Progenitor DifferentiationT;SIRPA;TBX20;LIN28A;NOG;IRX4;BMP1;TBX5;ZFP42
Collagen biosynthesis and modifying enzymesTLL2;COL5A2;ADAMTS2;TLDC2;EMID2;COL4A5;COL28A1A;LEPREL1;BMP1B
Collagen formationPCOLCEB;PCOLCE2;COL5A3B;COL9A1;SERPINH1B;BMP1;COL5A3A;CD151;COL9A1A
Crosslinking of collagen fibrilsTLL2;LOXL4;PCOLCE;LOXL2;LOXL1;BMP1A;ABHD1;BMP1B;LOX
Degradation of the extracellular matrixMMP10;TPSAB1;ADAMTS1;MMP17;CTSS;MGC174155;FURINB;CAPNS1;BMP1A

BMP1 has several biochemical functions, for example, calcium ion binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP1 itself. We selected most functions BMP1 had, and list some proteins which have the same functions with BMP1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingPCDH2AB9;OVAL;PLA2G5;FKBP9;C1rb;C1RA;SYT16;C2CD4A;CDHR1
cytokine activityNDR2;IFNK;CCL4;GDF11;TNFSF4;CSF1B;IFNT2;CTF1;TNFSF15
growth factor activityCSF2;INHBAA;FGF12A;FGF16;FGF12;IL5;FGF2;IL6;FGF14
metalloendopeptidase activityMMP25;Adam6;ADAM10B;NPSN;MEP1A.1;PITRM1;MMP11;ADAM1B;MMP3
metallopeptidase activityLNPEP;ADAM2;CNDP2;ADAM25;PAPLNB;ADAMTS1;Npepo;ANPEPB;ADAM17
peptidase activityTMPRSS4A;NOTS;HE1B;ADAM1B;PLAUA;CELA3B;DESI2;Shh;OTUD4
protein bindingTIMM21;AJUBA;SEC63;BICD1;DMBT1;RFWD3;ATP6V1F;PRKAR2A;KIAA1279
zinc ion bindingDTX4;RGN;RBM10;ZNRF2B;CAR5A;TXNDC17;BTR12;PDZRN3;ANKIB1A

BMP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP1.

MSTN; CHRD; TP53; ADRA1A; YLPM1; GEM; Uso1

Purushotham, S; Deivanayagam, C; et al. Cloning, expression and purification of the SRCR domains of glycoprotein 340. PROTEIN EXPRESSION AND PURIFICATION 90:67-73(2013).
Grgurevic, L; Macek, B; et al. Bone morphogenetic protein (BMP)1-3 enhances bone repair. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 408:26-+(2011).
TGF
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