BMP15

  • Official Full Name

    bone morphogenetic protein 15

  • Overview

    The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming;growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and;differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular;development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause;of ovarian dysgenesis 2.
  • Synonyms

    BMP15; bone morphogenetic protein 15; GDF9B; BMP-15; GDF-9B; growth/differentiation factor 9B; ODG2; POF4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • Mammalian Cell
  • C
  • His
  • His (Fc)
  • Avi
  • Myc
  • His(C
  • ter)
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BMP15-579H Active Recombinant Human Bone Morphogenetic Protein 15 CHO N/A
Human BMP15-010H Active Recombinant Human BMP15 Protein E.coli
Human BMP15-545H Recombinant Human BMP15 protein, His-tagged E.coli His Thr266~Ser388
Human BMP15-405H Recombinant Human BMP15 Mammalian Cell His
Human BMP15-66HCL Recombinant Human BMP15 lysate HEK293 N/A
Human BMP15-821H Recombinant Human BMP15 protein, His&Myc-tagged E.coli His&Myc 268-392aa
Human BMP15-2550H-B Recombinant Human BMP15 Protein Pre-coupled Magnetic Beads HEK293
Human BMP15-2550H Recombinant Human BMP15 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human BMP15-10H Recombinant Active Human BMP15 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human BMP15-313H Active Recombinant Human BMP15 Protein (Gln268-Arg392), C-His tagged, Animal-free, Carrier-free E.coli C-His Gln268-Arg392
Human BMP15-0777H Recombinant Human BMP15 Protein (Thr266-Ser388), His tagged E.coli His Thr266-Ser388
Human BMP15-266H Recombinant Human BMP15 Protein, His-tagged E.coli His Thr266~Ser388
Mouse Bmp15-267M Recombinant Mouse Bmp15 Protein, His-tagged E.coli His Ser274~Thr390
Rat Bmp15-268R Recombinant Rat Bmp15 Protein, His-tagged E.coli His Cys269~Arg391
Zebrafish BMP15-2687Z Recombinant Zebrafish BMP15 Mammalian Cell His
Chicken BMP15-1726C Recombinant Chicken BMP15 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

BMP15 involved in several pathways and played different roles in them. We selected most pathways BMP15 participated on our site, such as Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ovarian steroidogenesisACOT2;IGF1;INS1;PRKACA;FSHB;HSD3B4;SCARB1;HSD3B1;LHB

BMP15 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP15 itself. We selected most functions BMP15 had, and list some proteins which have the same functions with BMP15. You can find most of the proteins on our site.

Function Related Protein
cytokine activityCtf2;IFN-a;IFNG1-2;WNT2;WNT7A;NDP;IL19;CD70;TNFSF14
growth factor activityGDF7;FGF8B;GDF6;FGF10A;FGF14;TGFA;IGF2A;TIMP1;FGF5
transforming growth factor beta receptor bindingGDF7;BMP15;GDF15;GDF10;LFT2;SMAD3;GDF5;SPAW;AMH

BMP15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP15 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP15.

Research Area

Related articles

Lin, JY; Pitman-Crawford, JL; et al. Effects of species differences on oocyte regulation of granulosa cell function. REPRODUCTION 144:557-567(2012).
Jin, M; Yu, YQ; et al. An update on primary ovarian insufficiency. SCIENCE CHINA-LIFE SCIENCES 55:677-686(2012).
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