Active Recombinant Human BMP15 Protein
Cat.No. : | BMP15-010H |
Product Overview : | The mature recombinant human BMP-15 protein consists of 125 amino acids (268-392) without tag was expressed in E. coli. |
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Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Measured by its ability to induce Smad3 phosphorylation in P19 mouse embryonal carcinoma cells. Approximately 10 ng/mL can effectively induce Smad3 phosphorylation. |
Molecular Mass : | 14 kDa |
Product-Related Proteins : | 268-392 |
Endotoxin : | < 0.1 EU/μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | At -80 centigrade. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | PBS |
Protein length : | 268-392 |
Gene Name : | BMP15 bone morphogenetic protein 15 [ Homo sapiens (human) ] |
Official Symbol : | BMP15 |
Synonyms : | BMP15; bone morphogenetic protein 15; ODG2; POF4; GDF9B; bone morphogenetic protein 15; growth/differentiation factor 9B |
Gene ID : | 9210 |
mRNA Refseq : | NM_005448 |
Protein Refseq : | NP_005439 |
MIM : | 300247 |
UniProt ID : | O95972 |
Products Types
◆ Recombinant Protein | ||
Bmp15-267M | Recombinant Mouse Bmp15 Protein, His-tagged | +Inquiry |
BMP15-313H | Active Recombinant Human BMP15 Protein (Gln268-Arg392), C-His tagged, Animal-free, Carrier-free | +Inquiry |
BMP15-10H | Recombinant Active Human BMP15 Protein, His-tagged(C-ter) | +Inquiry |
BMP15-2550H | Recombinant Human BMP15 Protein, His (Fc)-Avi-tagged | +Inquiry |
Bmp15-268R | Recombinant Rat Bmp15 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
BMP15-66HCL | Recombinant Human BMP15 lysate | +Inquiry |
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Not For Human Consumption!
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