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Official Full Name calcitonin-related polypeptide alpha
Background This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms Alpha CGRP; CALC 1; CALC A; CALC1; CALCA; Calcitonin related polypeptide alpha; CGRP 1; CGRP; CGRP I; CGRP1; CGRPI; CT; Katacalcin; KC; MGC126648
    • Species :
    • Chicken
    • Dog
    • Eel
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CALCA-301179H Recombinant Human CALCA protein, GST-tagged E.coli GST
    Human CALCA-0289H Recombinant Human CALCA Protein, GST-Tagged Wheat Germ GST
    Human CALCA-047H Recombinant Human Calcitonin-Related Polypeptide Alpha, His-tagged E.coli His
    Human CALCA-101H Human Calcitonin Reference standard N/A
    Human CALCA-10658H Recombinant Human CALCA, GST-tagged E.coli GST
    Human CALCA-230H Recombinant Human CALCA, His-tagged E.coli His
    Human CALCA-236H Recombinant Human CALCA, Fc-tagged Human Cell Fc
    Human CALCA-317H Recombinant Human Calcitonin-related polypeptide alpha Human N/A
    Human CALCA-332H Recombinant Human CALCA protein E.coli N/A
    Human CALCA-519H Recombinant Human CALCA Protein, His-tagged HEK293 His
    Human CALCA-708H Recombinant Human CALCA Protein, His/GST-tagged E.coli His/GST
    Human CALCA-7895HCL Recombinant Human CALCA 293 Cell Lysate HEK293 N/A
    Human CALCA-817H Recombinant Human CALCA Protein, His-tagged E.coli His
    Human CALCA-8634H Recombinant Human CALCA, GST tagged E.coli GST
    Mouse CALCA-2643M Recombinant Mouse CALCA Protein Mammalian Cell His
    Mouse Calca-709M Recombinant Mouse Calca Protein, His-tagged E.coli His
    Mouse Calca-745M Recombinant Mouse Calca Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Calca-795M Recombinant Mouse Calca protein, His & GST-tagged E.coli His/GST
    Rat CALCA-1087R Recombinant Rat CALCA Protein Mammalian Cell His
    Rat Calca-796R Recombinant Rat Calca protein, His-tagged E.coli His
    Dog CALCA-707D Recombinant Dog CALCA Protein, His-tagged E.coli His
    Chicken CALCA-3807C Recombinant Chicken CALCA Mammalian Cell His
    Chicken CALCA-794C Recombinant Chicken CALCA protein, His-tagged E.coli His
    Zebrafish CALCA-601Z Recombinant Zebrafish CALCA Mammalian Cell His
    Eel CALCA-91E Eel Calcitonin Reference standard N/A

    calca involved in several pathways and played different roles in them. We selected most pathways calca participated on our site, such as Amyloid formation, Calcitonin-like ligand receptors, Class B/2 (Secretin family receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with calca were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amyloid formation SEMG1; NAT8; HIST4H4; TTR; CEACAM21; LTF; APCS; SAA1; HIST2H3C; ODAM
    Calcitonin-like ligand receptors CALCA; ADM; RAMP3; CALCRL; ADM2; RAMP2; CALCB; RAMP1; ADM2A
    Class B/2 (Secretin family receptors) PTHLH; EMR1; CRHR1; EMR3; GNB3A; CRHB; RCA2.1; RAMP1; EMR4; FZD10
    G alpha (s) signalling events NPS; PTH; ADCYAP1R1; VIP2; PTHLHA; ADORA2A; RXFP2; ADCYAP1; DRD5; CRHB
    GPCR downstream signaling ARHGEF17; RHOGA; GPR4; OR7D2; CCK; DRD5; RXFP2; CRHR1; ABHD12; CCL19A.2
    GPCR ligand binding PTH; CXCL13; FZD10; ADM; SCT; OPN4.1; CCL27; CGA; TAC2; CNR1
    Metabolism of proteins TIMM8A; INHBAA; GRPEL2; MCFD2; CPA3; NSFA; SFTPBB; SMC5; ATPBD4; GFER

    calca has several biochemical functions, for example, calcitonin receptor binding, hormone activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by calca itself. We selected most functions calca had, and list some proteins which have the same functions with calca. You can find most of the proteins on our site.

    Function Related Protein
    calcitonin receptor binding RAMP1; CALCA
    hormone activity NPPC; PYY; INSL6; GNRH2; GNRH3; SST; LEP; POMCB; SST2; EDN1
    identical protein binding PRDX3; DAPK2; ALS2CL; CHMP4A; ZBTB16; ACTG1; CAV1; IFI203; CLDNG; TPCN1
    protein binding NDUFAF1; BEX2; FGFR1OP2; SAP30L; RIPK2; KCNJ4; ATP6V1C2; CLEC18A; NEK9; HNRNPH2
    protein complex binding CDK5RAP2; EP300; YWHAB; AKAP5; MTHFR; SREBF1; ITGB1BP1; PTPRF; PPIB; PDCL
    receptor binding PEX14; NOS2; PTK2AA; CYTL1; ASIP; CTNND1; CD72; TIGIT; FZD8; CNPY4

    calca has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with calca here. Most of them are supplied by our site. Hope this information will be useful for your research of calca.


    Tavares, E; Maldonado, R; et al. Immunoneutralization of Endogenous Aminoprocalcitonin Attenuates Sepsis-Induced Acute Lung Injury and Mortality in Rats. AMERICAN JOURNAL OF PATHOLOGY 184:3069-3083(2014).
    Camacho, CP; Lindsey, SC; et al. Measurement of Calcitonin and Calcitonin Gene-Related Peptide mRNA Refines the Management of Patients with Medullary Thyroid Cancer and May Replace Calcitonin-Stimulation Tests. THYROID 23:308-316(2013).

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