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Recombinant Human CALCA Protein, His-tagged

Cat.No. : CALCA-519H
Product Overview : Recombinant human CALCA (NP_001732.1) (Met1-Asn141) was expressed with a polyhistidine tag at the C-terminus.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Ala 26
Form : Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Molecular Mass : The recombinant human CALCA consists 127 amino acids and predicts a molecular mass of 14.2 kDa.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >85 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : CALCA calcitonin-related polypeptide alpha [ Homo sapiens ]
Official Symbol : CALCA
Synonyms : CALCA; calcitonin-related polypeptide alpha; CALC1, calcitonin 1; calcitonin; calcitonin gene-related peptide 1; calcitonin; katacalcin; calcitonin 1; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; CT; KC; CGRP; CALC1; CGRP1; CGRP-I; MGC126648;
Gene ID : 796
mRNA Refseq : NM_001033952
Protein Refseq : NP_001029124
MIM : 114130
UniProt ID : P01258
Chromosome Location : 11p15.2
Pathway : Amyloids, organism-specific biosystem; Calcitonin-like ligand receptors, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; Disease, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the chemical structure of calcitonin, and how does it regulate calcium levels in the body? 05/26/2021

CALCA is a peptide hormone. It regulates calcium levels by reducing bone resorption, which lowers blood calcium levels, and by enhancing calcium excretion by the kidneys.

How is calcitonin synthesized from the CALCA gene? 10/14/2020

Calcitonin is synthesized from the CALCA gene through tissue-specific alternative RNA splicing of gene transcripts and cleavage of inactive precursor proteins.

What is the role of calcitonin gene-related peptide (CGRP), another product of CALCA? 11/23/2019

CGRP functions as a vasodilator and plays a role in antimicrobial defense in addition to its role in neurovascular regulation.

How is CALCA production affected by changes in serum calcium levels? 08/08/2018

An increase in serum calcium levels stimulates the secretion of CALCA to help reduce the excess calcium in the bloodstream.

Can you explain the relationship betweCALCA and parathyroid hormone (PTH)? 06/02/2018

CALCA and PTH are antagonistic hormones. PTH increases blood calcium levels, whereas calcitonin reduces them. They work together to maintain calcium homeostasis.

Customer Reviews (3)

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Reviews
05/06/2022

    Quality laboratory materials, on-time delivery, and the best customer service.

    01/22/2021

      Impressed by the product quality and quick delivery. Great job!

      07/11/2019

        I love their laboratory products, and the delivery is super speedy.

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