Recombinant Human CALCA Protein, His-tagged
Cat.No. : | CALCA-817H |
Product Overview : | Recombinant Human CALCA, transcript variant 2, fused with His tag at C-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4 |
Molecular Mass : | 10.5kD |
AA Sequence : | YVQMKASELEQEQEREGSSLDSPRS KRCGNLSTCMLGTYTQDFNKFHTFP QTAIGVGAPGKKRDMSSDLERDHRP HVSMPQNANVEHHHHHH |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | CALCA calcitonin-related polypeptide alpha [ Homo sapiens ] |
Official Symbol : | CALCA |
Synonyms : | CALCA; calcitonin-related polypeptide alpha; CALC1, calcitonin 1; calcitonin; calcitonin gene-related peptide 1; calcitonin; katacalcin; calcitonin 1; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; CT; KC; CGRP; CALC1; CGRP1; CGRP-I; MGC126648; |
Gene ID : | 796 |
mRNA Refseq : | NM_001033952 |
Protein Refseq : | NP_001029124 |
MIM : | 114130 |
UniProt ID : | P01258 |
Products Types
◆ Recombinant Protein | ||
CALCA-07H | Recombinant Human CALCA Protein | +Inquiry |
CALCA-0064H | Recombinant Human CALCA Protein | +Inquiry |
Calca-862R | Recombinant Rat Calca Protein, His&SUMO-tagged | +Inquiry |
Calca-745M | Recombinant Mouse Calca Protein, MYC/DDK-tagged | +Inquiry |
CALCA-0063H | Recombinant Human CALCA Protein | +Inquiry |
◆ Lysates | ||
CALCA-7895HCL | Recombinant Human CALCA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCALCA is a peptide hormone. It regulates calcium levels by reducing bone resorption, which lowers blood calcium levels, and by enhancing calcium excretion by the kidneys.
Calcitonin is synthesized from the CALCA gene through tissue-specific alternative RNA splicing of gene transcripts and cleavage of inactive precursor proteins.
CGRP functions as a vasodilator and plays a role in antimicrobial defense in addition to its role in neurovascular regulation.
An increase in serum calcium levels stimulates the secretion of CALCA to help reduce the excess calcium in the bloodstream.
CALCA and PTH are antagonistic hormones. PTH increases blood calcium levels, whereas calcitonin reduces them. They work together to maintain calcium homeostasis.
Customer Reviews (3)
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Impressed by the product quality and quick delivery. Great job!
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