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CCNB2

  • Official Full Name

    cyclin B2

  • Overview

    Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
  • Synonyms

    CCNB2; cyclin B2; G2/mitotic-specific cyclin-B2; HsT17299;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCNB2-0654H Recombinant Human CCNB2 Protein, His-Tagged E.coli His
Human CCNB2-6835H Recombinant Human Cyclin B2, His-tagged E.coli His 1-398aa
Human CCNB2-27516TH Recombinant Human CCNB2, His-tagged E.coli His
Human CCNB2-10858H Recombinant Human CCNB2, His-tagged E.coli His 1-243a.a.
Human CCNB2-0655H Recombinant Human CCNB2 Protein, GST-Tagged Wheat Germ GST
Human CCNB2-7716HCL Recombinant Human CCNB2 293 Cell Lysate HEK293 N/A
Human CCNB2-0895H Recombinant Human CCNB2 Protein (Val58-Ser398), N-His tagged E.coli N-His Val58-Ser398
Human CCNB2-882H Recombinant Human CCNB2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CCNB2-2962HF Recombinant Full Length Human CCNB2 Protein, GST-tagged In Vitro Cell Free System GST 398 amino acids
Mouse CCNB2-2985M Recombinant Mouse CCNB2 Protein Mammalian Cell His
Mouse CCNB2-1402M Recombinant Mouse CCNB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ccnb2-797M Recombinant Mouse Ccnb2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse CCNB2-1402M-B Recombinant Mouse CCNB2 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey CCNB2-374C Recombinant Cynomolgus CCNB2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CCNB2-122C Recombinant Cynomolgus Monkey CCNB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey CCNB2-122C-B Recombinant Cynomolgus Monkey CCNB2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CCNB2-9916Z Recombinant Zebrafish CCNB2 Mammalian Cell His
Chicken CCNB2-1188C Recombinant Chicken CCNB2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CCNB2 Related Articles
  • CCNB2 Related Research Area

CCNB2 involved in several pathways and played different roles in them. We selected most pathways CCNB2 participated on our site, such as FoxO signaling pathway, Cell cycle, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FoxO signaling pathwayNRAS;TGFBR2;AKT3A;PIK3CA;G6PC3;INSB;KRAS;RAF1A;HRAS
Cell cycleDBF4;RAD9B;CLIP1;KIF2C;NIPBLA;ANAPC7;CENPP;SKP2;B9D2
Oocyte meiosisCPEB1;PPP1CA;PPP2R5CB;CAMK2D1;PPP1CAA;PPP3CA;ADCY2B;PRKACBB;MAPK1
p signaling pathwayCASP8;GADD45BA;SHISA5;TP53AIP1;CCNB3;SIAH1A;CCNB2;BAI1;GADD45BB
Progesterone-mediated oocyte maturationPRKACB;PIK3CB;IGF1RB;GNAI1;RAF1A;MAPK13;PIK3R3;Adcy4;RPS6KA3B
HTLV-I infectionLTBR;POLD4;CD3E; CD3D;AKT2;GM-CSF;PPP3CB;TBP;CD3G;CCND3

CCNB2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNB2 itself. We selected most functions CCNB2 had, and list some proteins which have the same functions with CCNB2. You can find most of the proteins on our site.

Function Related Protein
protein bindingVGLL4;RASSF1;MYC;ALDOA;CLDN7;LRRC6;PNRC2;RINT1;TEAD3

CCNB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNB2.

FLNA; CDK1; Cdk1; CDK2; CCNB1

Park, KS; Bayles, I; et al. Transcription Elongation Factor ELL2 Drives Ig Secretory-Specific mRNA Production and the Unfolded Protein Response. JOURNAL OF IMMUNOLOGY 193:4663-4674(2014).
Xue, CY; Chen, YQ; et al. EphB4 expression in pterygium is associated with microvessel density. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 7:4008-4015(2014).
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