CCNB2
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Official Full Name
cyclin B2
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Overview
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. -
Synonyms
CCNB2; cyclin B2; G2/mitotic-specific cyclin-B2; HsT17299;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus Monkey
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
CCNB2 involved in several pathways and played different roles in them. We selected most pathways CCNB2 participated on our site, such as FoxO signaling pathway, Cell cycle, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| FoxO signaling pathway | SGK1;MAPK9;RAF1B;SGK3;ATG12;MAPK8B;PRKAG3B;FOXO6;RAG2 |
| Cell cycle | CDCA5;GSK3B;CUL1A;RANGAP1B;NDEL1;FOXM1;OFD1;GOLGA2;MLF1IP |
| Oocyte meiosis | PGR;PTTG1;CALML5;PPP1CAB;PPP3CCB;CDC16;INS2;MAPK3;CUL1B |
| p signaling pathway | SIAH1A;GADD45BA;CCNE2;IGFBP3;PMAIP1;CASP3B;GADD45AA;SHISA5;BAXA |
| Progesterone-mediated oocyte maturation | MAPK9;RPS6KA3A;CPEB1B;PIK3R3B;MAPK8;RAF1B;MAPK14A;PIK3R2;MAPK3 |
| HTLV-I infection | VCAM1;H2-Q10;XIAP;CREM;ANAPC5;HLA-E;GM-CSF;SLC25A31;SMAD4 |
CCNB2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNB2 itself. We selected most functions CCNB2 had, and list some proteins which have the same functions with CCNB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MDM2;HSPA14;MOCS3;ZNF302;C17orf81;SUMO1;RPL4;CNKSR3;RMND1 |
CCNB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNB2.
FLNA; CDK1; Cdk1; CDK2; CCNB1
Research Area
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