| Description : |
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
45.3 kDa |
| AA Sequence : |
MALLRRPTVSSDLENIDTGVNSKVK SHVTIRRTVLEEIGNRVTTRAAQVA KKAQNTKVPVQPTKTTNVNKQLKPT ASVKPVQMEKLAPKGPSPTPEDVSM KEENLCQAFSDALLCKIEDIDNEDW ENPQLCSDYVKDIYQYLRQLEVLQS INPHFLDGRDINGRMRAILVDWLVQ VHSKFRLLQETLYMCVGIMDRFLQV QPVSRKKLQLVGITALLLASKYEEM FSPNIEDFVYITDNAYTSSQIREME TLILKELKFELGRPLPLHFLRRASK AGEVDVEQHTLAKYLMELTLIDYDM VHYHPSKVAAAASCLSQKVLGQGKW NLKQQYYTGYTENEVLEVMQHMAKN VVKVNENLTKFIAIKNKYASSKLLK ISMIPQLNSKAVKDLASPLIGRSTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
