CD37

  • Official Full Name

    CD37 molecule

  • Overview

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family.;Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains.;The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,;growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and;other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing;results in multiple transcript variants encoding different isoforms.
  • Synonyms

    CD37; CD37 molecule; CD37 antigen; leukocyte antigen CD37; TSPAN26; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37; GP52-40; MGC120234;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Bovine
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • In vitro E. coli expression system
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • Fc
  • His (Fc)
  • Avi
  • human|IgG1|Fc
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD37-486H Active Recombinant Human CD37 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human CD37-661H Recombinant Human CD37 protein, His-tagged HEK293 His Arg 112 - Asn 241
Human CD37-69H Recombinant Human CD37 protein, Fc-tagged HEK293 human/IgG1/Fc Ala113-Apn240
Human CD37-10949H Recombinant Human CD37 protein, His-tagged E.coli His 101 - 250 aa
Human CD37-7677HCL Recombinant Human CD37 293 Cell Lysate HEK293 N/A
Human CD37-7678HCL Recombinant Human CD37 293 Cell Lysate HEK293 N/A
Human CD37-70H Recombinant Human CD37 protein, His-tagged HEK293 His Arg 112 - Asn 241
Human CD37-154H Recombinant Human CD37 Protein, Fc-tagged HEK293 Fc 281
Human CD37-193H Recombinant Human CD37 Protein, C-His-tagged E.coli C-His
Human CD37-2958H Recombinant Human CD37 protein, Fc-tagged HEK293 Fc Ala 113-Asn 240
Human CD37-71H Recombinant Human CD37 protein, Fc-tagged HEK293 Fc Arg 112 - Asn 241
Human CD37-4806H Active Recombinant Human CD37 Full Length Transmembrane protein(VLPs) HEK293 N/A Met 1 - Arg 281
Human CD37-0943H Recombinant Human CD37 Protein (Thr110-Asn241), N-His tagged E.coli N-His Thr110-Asn241
Human CD37-71HF Recombinant Human CD37 protein, Fc-tagged, FITC-Labeled HEK293 Fc Arg 112 - Asn 241
Human CD37-5348H Recombinant Human CD37 Protein (Arg112-Asn241), C-His tagged Mammalian cells C-His Arg112-Asn241
Human CD37-0295H Recombinant Human CD37 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-281aa
Mouse Cd37-896M Recombinant Mouse Cd37 Protein, Fc-tagged HEK293 Fc
Rat CD37-1248R Recombinant Rat CD37 Protein Mammalian Cell His
Rat CD37-906R Recombinant Rat CD37 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CD37-906R-B Recombinant Rat CD37 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL611BF Recombinant Full Length Bovine Leukocyte Antigen Cd37(Cd37) Protein, His-Tagged E.coli expression system His Full Length (1-280aa)
Bovine CD37-1482B Recombinant Bovine CD37 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-280aa
Homo sapiens (Human) RFL19534HF Recombinant Full Length Human Leukocyte Antigen Cd37(Cd37) Protein, His-Tagged E.coli expression system His Full Length (1-281)
Mus musculus (Mouse) RFL29122MF Recombinant Full Length Mouse Leukocyte Antigen Cd37(Cd37) Protein, His-Tagged E.coli expression system His Full Length (1-281)
Rattus norvegicus (Rat) RFL20204RF Recombinant Full Length Rat Leukocyte Antigen Cd37(Cd37) Protein, His-Tagged E.coli expression system His Full Length (1-281)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CD37 involved in several pathways and played different roles in them. We selected most pathways CD37 participated on our site, such as Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD37 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hematopoietic cell lineageITGA2B;FCGR1;ITGA2;CD8B;Flt3l;CD19;IL11RA2;IL6;EPO

CD37 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD37 itself. We selected most functions CD37 had, and list some proteins which have the same functions with CD37. You can find most of the proteins on our site.

Function Related Protein
protein bindingSIK3;ZNF404;CST9L;ASTE1;PTPN7;LDHB;DNA2;EIF2B5;ERCC4

CD37 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD37 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD37.

LYN; PTPN6; SYK; PIK3CD; PIK3CG; KARS

Research Area

Related articles

Pagel, JM; Spurgeon, SE; et al. Otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, for relapsed or refractory NHL patients. BRITISH JOURNAL OF HAEMATOLOGY 168:38-45(2015).
Deckert, J; Ponte, JF; et al. Preclinical Mechanistic Studies Investigating Neutrophil and Lymphoid Cell Depletion By IMGN529, a CD37-Targeting Antibody-Drug Conjugate (ADC). BLOOD 124:-(2014).
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