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CDC20

  • Official Full Name

    cell division cycle 20 homolog (S. cerevisiae)

  • Overview

    CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.
  • Synonyms

    CDC20; cell division cycle 20 homolog (S. cerevisiae); CDC20A; p55CDC; MGC102824; bA276H19.3; cell division cycle protein 20 homolog; OTTHUMP00000008571; OTTHUMP00000008572; CDC20 cell division cycle 20 homolog; Cdc 20; fizzy;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • MYC
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDC20-0910H Recombinant Human CDC20 Protein, GST-Tagged Wheat Germ GST
Human CDC20-27897TH Recombinant Human CDC20 Wheat Germ N/A 100 amino acids
Human CDC20-7668HCL Recombinant Human CDC20 293 Cell Lysate HEK293 N/A
Human CDC20-001H Recombinant Human CDC20 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CDC20-553H Recombinant Human CDC20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CDC20-5841H Recombinant Human CDC20 protein, His&Myc-tagged E.coli His&Myc 1-499aa
Human CDC20-553H-B Recombinant Human CDC20 Protein Pre-coupled Magnetic Beads HEK293
Human CDC20-715H Recombinant Human CDC20 Protein, His-tagged E.coli N-His Gln218-Arg471
Human CDC20-3132HF Recombinant Full Length Human CDC20 Protein, GST-tagged In Vitro Cell Free System GST 499 amino acids
Human CDC20-1042HFL Recombinant Full Length Human CDC20 Protein, C-Flag-tagged Mammalian cells Flag
Mouse Cdc20-352M Recombinant Mouse Cdc20 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CDC20-1270R Recombinant Rat CDC20 Protein Mammalian Cell His
Rat CDC20-928R Recombinant Rat CDC20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CDC20-928R-B Recombinant Rat CDC20 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CDC20-758R Recombinant Rhesus monkey CDC20 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CDC20-584R-B Recombinant Rhesus Macaque CDC20 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CDC20-584R Recombinant Rhesus Macaque CDC20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CDC20-12309Z Recombinant Zebrafish CDC20 Mammalian Cell His
Chicken CDC20-1674C Recombinant Chicken CDC20 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CDC20 Related Articles

CDC20 involved in several pathways and played different roles in them. We selected most pathways CDC20 participated on our site, such as Cell cycle, Oocyte meiosis, Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell cycleOIP5;KIF2B;CDKN2C;CEP63;CCNH;SMC2;CDK2;SMC1A;CSNK2A1
Oocyte meiosisRPS6KA6;AURKA;PRKACB;CUL1B;CDC25C;ANAPC4;IGF1R;CAMK2D1;RPS6KA3B
Ubiquitin mediated proteolysisUBE2E3;NHLRC1;SOCS1A;TRIP12;UBA1;FBXO4;CDC20;MDM2;HERC4
HTLV-I infectionLTBR;HLA-DMA;IL1R2;EGR2;WNT8A;LTA;DVL1;H2-AB1;RAN
Viral carcinogenesisHLA-F;STAT5A;NFKB2;VDAC3;KAT2B;MAD1L1;EIF2AK2;RBPJ;HIST1H4B

CDC20 has several biochemical functions, for example, enzyme binding, histone deacetylase binding, protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC20 itself. We selected most functions CDC20 had, and list some proteins which have the same functions with CDC20. You can find most of the proteins on our site.

Function Related Protein
enzyme bindingRPS2;PARP1;ATF7;DIS3L;TULP3;NOXO1;CYP2E1;HIST1H2AL;BIRC7
histone deacetylase bindingPARK2;ANKRA2;BCOR;WDTC1;HES1;D7ERTD443E;MAGEA2;DDX20;MEF2A
protein C-terminus bindingSIAH1A;PPP2CB;PEX16;EFHC1;CDC20;ECM1;TNNI3K;CTGF;ERCC2
protein bindingZNF544;ACSF2;RNF19B;CNEP1R1;KIF3B;C17orf59;ZFP259;CA1;TEF

CDC20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC20 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC20.

BUB1B; MAD2L1

Lu, L; Hu, SH; et al. The HECT Type Ubiquitin Ligase NEDL2 Is Degraded by Anaphase-promoting Complex/Cyclosome (APC/C)-Cdh1, and Its Tight Regulation Maintains the Metaphase to Anaphase Transition. JOURNAL OF BIOLOGICAL CHEMISTRY 288:35637-35650(2013).
Petra, H; Eva, H; et al. Molecular Profiling of Acute and Chronic Rejections of Renal Allografts. CLINICAL & DEVELOPMENTAL IMMUNOLOGY :-(2013).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
What are the potential side effects of inhibiting CDC20? 08/16/2021

Inhibiting CDC20 could potentially affect normal cell division, leading to adverse effects on healthy cells.

Could CDC20 be a prognostic marker for cancer? 04/02/2021

Some studies suggest that CDC20 levels might correlate with the prognosis of certain cancers, indicating the potential for predicting disease outcomes.

Are there any ongoing clinical trials related to CDC20? 08/29/2018

Several trials are exploring CDC20 inhibitors and their efficacy in cancer treatment.

How is CDC20 being targeted for therapeutic interventions? 06/27/2017

Research is investigating the inhibition of CDC20 as a potential strategy for cancer treatment.

Are there any medications targeting CDC20 currently available? 05/17/2016

No medications specifically targeting CDC20 have been approved, but research is ongoing in drug development.

Customer Reviews (3)

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Reviews
05/23/2022

    Its robust performance has significantly accelerated my research progress and contributed to the advancement of my scientific understanding.

    11/13/2021

      This protein has become an invaluable asset in my research, offering great versatility in its applications.

      11/07/2017

        The CDC20 protein stands out for its excellent quality, exceptional technical support, and wide range of applications.

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