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CETN2

  • Official Full Name

    centrin, EF-hand protein, 2

  • Overview

    Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome.The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.
  • Synonyms

    CETN2; centrin, EF-hand protein, 2; CALT; centrin-2; CEN2; 20kD calcium binding protein; caltractin; Caltractin isoform 1; centrin; centrin, EF hand protein, 2; Centrin2; CETN2_HUMAN; EF hand protein 2; EF-hand protein; OTTHUMP00000026058; caltractin (20kD calcium-binding protein);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Fc|His
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CETN2-3375H Recombinant Human Centrin, EF-Hand Protein, 2, His-tagged E.coli His
Human CETN2-1156H Recombinant Human CETN2 Protein, GST-Tagged Wheat Germ GST
Human CETN2-118H Recombinant Human CETN2, His tagged E.coli Fc/His
Human CETN2-27957TH Recombinant Human CETN2, His-tagged E.coli His 172 amino acids
Human CETN2-11129H Recombinant Human CETN2, His-tagged E.coli His 1-172a.a.
Human CETN2-639H Recombinant Human CETN2 Protein, His-tagged HEK293 His
Human CETN2-7561HCL Recombinant Human CETN2 293 Cell Lysate HEK293 N/A
Human CETN2-3289HF Recombinant Full Length Human CETN2 Protein, GST-tagged In Vitro Cell Free System GST 172 amino acids
Human CETN2-1812H Recombinant Human CETN2 protein, GST-tagged E.coli GST 1-172 aa
Human CETN2-0993H Recombinant Human CETN2 Protein (Met1-Leu171), N-His tagged E.coli N-His Met1-Leu171
Human CETN2-2235H Recombinant Human CETN2 protein, His-tagged E.coli His Met1-Tyr171
Human CETN2-2688H Recombinant Human CETN2 protein, His-SUMO-tagged E.coli His-SUMO 1-172aa
Human CETN2-754H Recombinant Human CETN2 Protein, His-tagged E.coli N-His Ala2-Leu171
Mouse CETN2-3339M Recombinant Mouse CETN2 Protein Mammalian Cell His
Mouse CETN2-1607M-B Recombinant Mouse CETN2 Protein Pre-coupled Magnetic Beads HEK293
Mouse CETN2-1607M Recombinant Mouse CETN2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CETN2-824R Recombinant Rhesus monkey CETN2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CETN2-650R-B Recombinant Rhesus Macaque CETN2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CETN2-650R Recombinant Rhesus Macaque CETN2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken CETN2-5019C Recombinant Chicken CETN2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CETN2 Related Articles

CETN2 involved in several pathways and played different roles in them. We selected most pathways CETN2 participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with CETN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Anchoring of the basal body to the plasma membraneACTR1A;TUBB4B;OFD1;RPGRIP1L;BBS13;NEK2;CENPJ;RAB3IP;CLASP1
Assembly of the primary ciliumB9D2;WDR35;SDCCAG8;TTC30B;SSTR3;DYNLL2A;ODF2;KIFAP3B;CEP76
Cell CycleNIPBLA;NDEL1A;CDKN2C;SMAD3A;ODF2B;FAM175A;CDC27;CDH1-A;CCNE1
Cell Cycle, MitoticCENPQ;DYRK1A;HAUS2;MLF1IP;CDT1;PMF1;MCM10;CDKN2D;NCAPD3
Centrosome maturationCSNK1E;CCP110;TUBGCP2;OFD1;TUBGCP5;CSNK1D;DCTN3;CEP63;DCTN1
DNA Damage Recognition in GG-NERACTL6A;INO80C;INO80;DDB1;COPS5;YY1;CETN2;PARP1;YY1A
DNA RepairCOPS7B;CHEK2;SMARCA5;ZBTB32;COPS7A;EYA4;COPS4;TDP1;PPP4R2A
Formation of Incision Complex in GG-NERUSP45;CETN2;DDB1;PARP2;DDB2;PIAS3;RNF111;CHD1L

CETN2 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding, calcium ion binding, heterotrimeric G-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CETN2 itself. We selected most functions CETN2 had, and list some proteins which have the same functions with CETN2. You can find most of the proteins on our site.

Function Related Protein
G-protein beta/gamma-subunit complex bindingGNAZ;GNAI2;GNA14;Adcy4;GNAI2A;GNA12;GNAI2B;GNA15;GNA11B
calcium ion bindingPCDH2AA15;TBC1D9B;EFHD2;S100A13;PCDH2AC;HSPA5;SULF2;MAN1A1;SPTAN1
heterotrimeric G-protein bindingADORA1;CETN4;CETN1;ADRA2A;CETN2
microtubule bindingMAP1S;EML2;MAP2;DPYSL2B;KATNB1;GAS2L1;MTAP6;RGS14;KIF2A
protein bindingC18orf56;ORAI3;B4GALT7;ZNF524;NPDC1;JUN;SERINC1;SF3A2;NUP54

CETN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CETN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CETN2.

SFI1; SGSM1; POC5; PNMA5; CCP110; XPC

Lutz, W; Lingle, WL; et al. Phosphorylation of centrin during the cell cycle and its role in centriole separation preceding centrosome duplication. JOURNAL OF BIOLOGICAL CHEMISTRY 276:20774-20780(2001).
Laoukili, J; Perret, E; et al. Differential expression and cellular distribution of centrin isoforms during human ciliated cell differentiation in vitro. JOURNAL OF CELL SCIENCE 113:1355-1364(2000).
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