Recombinant Human Centrin, EF-Hand Protein, 2, His-tagged

• Cat.No.: CETN2-3375H
• Product Overview: Recombinant human CETN2 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography.MW = 21.9 kDa (192aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CETN2, also called caltractin, belongs to a family of calcium-binding proteins and is a structural component of the centrosome. This protein plays a role in nucleotide excision repair via association with xeroderma pigmentosum group C protein, suggesting possible coupling of cell division and nucleotide excision repair.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl, 1mM DTT.
• Purity: > 90% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MASNFKKANM ASSSQRKRMS PKPELTEEQK QEIREAFDLF DADGTGTIDV KELKVAMRAL GFEPKKEEIK KMISEIDKEG TGKMNFGDFL TVMTQKMSEK DTKEEILKAF KLFDDDETGK ISFKNLKRVA KELGENLTDE ELQEMIDEAD RDGDGEVSEQ EFLRIMKKTS LY.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Nucleotide excision repair; Cell Cycle, Mitotic

Gene Information

• Gene Name: CETN2 centrin, EF-hand protein, 2 [ Homo sapiens ]
• Synonyms: centrin, EF-hand protein, 2; CALT; CEN2; CETN2; centrin-2; caltractin (20kD calcium-binding protein); Caltractin isoform 1
• Gene ID: 1069
• mRNA Refseq: NM_004344
• Protein Refseq: NP_004335
• MIM: 300006
• UniProt ID: P41208
• Chromosome Location: Xq28
• Function: ATP binding; ATP-dependent helicase activity; G-protein beta/gamma-subunit binding; calcium ion binding; nucleic acid binding; protein binding