• Official Full Name

    carbohydrate (chondroitin 4) sulfotransferase 11

  • Background

    The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    CHST11; carbohydrate (chondroitin 4) sulfotransferase 11; carbohydrate sulfotransferase 11; C4ST; C4St 1; C4ST1; HSA269537; C4S-1; C4ST-1; Chondroitin 4 O sulfotransferase 1; Chondroitin 4 sulfotransferase; Chondroitin 4-O-sulfotransferase 1; Chondroitin 4-sulfotransferase 1; CHST 11; CHSTB_HUMAN; IgH/CHST11 fusion; OTTHUMP00000242139; OTTHUMP00000242140;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Rat
    • Rattus norvegicus (Rat)
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • Insect Cell
    • Insect Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Price
    Human CHST11-1295H Recombinant Human CHST11 Protein, GST-Tagged Wheat Germ GST
    Human CHST11-148H Recombinant Human CHST11 protein, His-tagged Insect Cells His
    Human CHST11-11224H Recombinant Human CHST11, His-tagged E.coli His
    Human CHST11-001HCL Recombinant Human CHST11 cell lysate Insect Cell N/A
    Human CHST11-301460H Recombinant Human CHST11 protein, GST-tagged E.coli GST
    Rat CHST11-1405R Recombinant Rat CHST11 Protein Mammalian Cell His
    Rat CHST11-1063R-B Recombinant Rat CHST11 Protein Pre-coupled Magnetic Beads HEK293
    Rat CHST11-1063R Recombinant Rat CHST11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rattus norvegicus (Rat) RFL2433RF Recombinant Full Length Rat Carbohydrate Sulfotransferase 11(Chst11) Protein, His-Tagged E.coli expression system His
    Rhesus Macaque CHST11-867R Recombinant Rhesus monkey CHST11 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CHST11-693R-B Recombinant Rhesus Macaque CHST11 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque CHST11-693R Recombinant Rhesus Macaque CHST11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Zebrafish CHST11-12090Z Recombinant Zebrafish CHST11 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    CHST11 involved in several pathways and played different roles in them. We selected most pathways CHST11 participated on our site, such as Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateB3GAT3;CHSY3;UST;DSE;CHST14;CHST11;B3GALT6;CSGALNACT1;CHST3

    CHST11 has several biochemical functions, for example, N-acetylgalactosamine 4-O-sulfotransferase activity, N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity, chondroitin 4-sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST11 itself. We selected most functions CHST11 had, and list some proteins which have the same functions with CHST11. You can find most of the proteins on our site.

    Function Related Protein
    N-acetylgalactosamine 4-O-sulfotransferase activityCHST3A;CHST3B;SULT1ST3;CHST11;HS6ST1B;SULT2ST3;HS6ST3B;SULT1ST4;CHST2A
    N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activityCHST15;CHST11
    chondroitin 4-sulfotransferase activityCHST12;CHST11

    CHST11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST11 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST11.

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